Search Results - "Bahram Pakzad"

Regulation of DNA methylation machinery by epi-miRNAs in human cancer: emerging new targets in cancer therapy by Karimzadeh, Mohammad Reza, Pourdavoud, Peyman, Ehtesham, Naeim, Qadbeigi, Mohaddese, Asl, Masood Movahedi, Alani, Behrang, Mosallaei, Meysam, Pakzad, Bahram

“…Disruption in DNA methylation processes can lead to alteration in gene expression and function that would ultimately result in malignant transformation. In…”
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MiR-196: emerging of a new potential therapeutic target and biomarker in colorectal cancer by Pourdavoud, Peyman, Pakzad, Bahram, Mosallaei, Meysam, Saadatian, Zahra, Esmaeilzadeh, Emran, Alimolaie, Asma, Shaygannejad, Alireza

“…Deregulation of microRNAs, as key elements in colorectal cancer (CRC) pathogenesis, is correlated with various stages of this cancer. miR-196 is involved in…”
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Differentially methylation of IFI44L gene promoter in Iranian patients with systemic lupus erythematosus and rheumatoid arthritis by Salesi, Mansour, Dehabadi, Milad Hayeri, Salehi, Rasoul, Salehi, Amirhossein, Pakzad, Bahram

“…Background Systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are multisystemic autoimmune diseases with multifactorial nature. Considering the…”
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Impact of miRNA-binding site polymorphisms in STAT3 gene on occurrence and clinical characteristics of systemic lupus erythematosus by Salehi, Amirhossein, Nasrollahzadeh Sabet, Mehrdad, Esmaeilzadeh, Emran, Mousavi, Maryam, Karimi, Jalal, Pakzad, Bahram

“…Background Signal transducer and activator of transcription 3 (STAT3) is a major regulator of immune response and chronic inflammatory conditions acting…”
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Three functional variants in the NLRP3 gene are associated with susceptibility and clinical characteristics of systemic lupus erythematosus by Ehtesham, Naeim, Zare Rafie, Maryam, Esmaeilzadeh, Emran, Dehani, Mohammad, Davar, Saeideh, Mosallaei, Meysam, Pakzad, Bahram, Ghorashi, Tahereh, Darvish, Hossein, Soosanabadi, Mohsen

“…Objective Nod-like receptor pyrin domain containing 3 (NLRP3) gene encodes an intracellular receptor whose dysregulation in systemic lupus erythematosus (SLE)…”
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Predictors of relapse in granulomatosis with polyangiitis: a multi-center study by Safari, Sara, Alesaeidi, Samira, Pakzad, Bahram, Abbaspour, Sina

“…Background Granulomatosis with polyangiitis (GPA) is a rare systemic vasculitis. Its severity ranges from indolent disease to fulminant that may cause death…”
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Strong association of common variants in the miRNA-binding site of NOD2 gene with clinicopathological characteristics and disease activity of systemic lupus erythematosus by Esmaeilzadeh, Emran, Saghi, Mostafa, Hassani, Mehdi, Davar, Saeideh, Alani, Behrang, Pakzad, Bahram, Ghobakhloo, Sepideh, Khosravi, Sharifeh, Sabet, Mehrdad Nasrollahzadeh

“…Introduction/objectives Systemic lupus erythematosus (SLE) is a multifactorial systemic autoimmune disease, in which genetic susceptibility plays a pivotal…”
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Investigating the Decreased Bone Density Prevalence in People with Common Risk Factors Referred to Al-Zahra Educational-Medical Center in Isfahan City Years of 2018 and 2019 by Mousavi, Maryam, Pakzad, Bahram, Ebrahimian, Maryam

“…Introduction: Osteoporosis is a disease in skeletal system that is recognized by a lack of bone density and degeneration of bone tissue and can lead to…”
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Evaluation of Frequency Pattern of Risk Factors for Decreased Bone Mineral Density in Postmenopausal Women Referred to the Bone Mineral Density Assessment Center of Al-Zahra Hospital in Isfahan during Years 2018 and 2019 by Pakzad, Bahram, Parsaei, Golareh, Karimi, Jalal

“…Introduction: Osteoporosis is a systemic skeletal disease in which the internal structure and ability of bone to repair its daily damage is impaired. Menopause…”
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Assessment of the association between TNIP1 polymorphism with clinical features and risk of systemic lupus erythematosus by Azhdari, Sara, Saghi, Mostafa, Alani, Behrang, Zare Rafie, Maryam, Kenarangi, Taiebe, Nasrollahzadeh Sabet, Mehrdad, Pakzad, Bahram, Ghorashi, Tahereh, Gholami, Milad, Soosanabadi, Mohsen

“…Objective Over the past decades, TNIP1 has been identified as a strong risk locus in multiple genome-wide association studies (GWAS), spanning multiple…”
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Single Nucleotide Polymorphism rs2075876 in AIRE Gene is a Strong Rheumatoid Arthritis Determinant by Salesi, Mansour, Noormohamadi, Elham, Pakzad, Bahram, Yousefisadr, Farzaneh, Salehi, Rasoul

“…Rheumatoid arthritis (RA) is a progressive and common autoimmune disease with multifactorial etiology. Several pieces of research show that genetic factors…”
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Association of rs3135500 and rs3135499 Polymorphisms in the MicroRNA-binding Site of Nucleotide-binding Oligomerization Domain 2 (NOD2) Gene with Susceptibility to Rheumatoid Arthritis by Naeim Ehtesham, Behrang Alani, Deniz Mortazavi, Sara Azhdari, Taiebe Kenarangi, Emran Esmaeilzadeh, Bahram Pakzad

“…The nucleotide-binding oligomerization domain 2 (NOD2) is the key regulator of inflammatory responses and has been involved in the pathogenesis of rheumatoid…”
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C-reactive protein, D-dimer, erythrocyte sedimentation rate, and troponin in intensive care unit patients with COVID-19 in Iran by Salehi, Hassan, Pakzad, Bahram, Salehi, Marzieh, Abbasi, Saeed, Salehi, Mohammad, Naeini, Maryam

“…Background: The coronavirus disease 2019 (COVID-19) pandemic in Iran has led to a lack of intensive care unit (ICU) facilities. This study examines C-reactive…”
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T-Score Discordance Between Hip and Spine in Diagnosis of Osteoporosis in Patients From Iranian Population by Beigy, Hajar, Mousavi, Maryam, Karimi, Jalal, Karimzadeh, Hadi, Arezomandi, Nima, Pakzad, Bahram

“…Today, osteoporosis is a major healthcare system problem globally. Each year, osteoporosis leads to more than 8.9 million fractures. In practice, osteoporosis…”
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Importance of STAT3 Polymorphisms on the Risk and Clinical Characteristics of Rheumatoid Arthritis by Salehi, Amirhossein, Hazrati, Ebrahim, Ranjbar, Hamta, Behroozi, Javad, Pakzad, Bahram, Mousavi, Maryam, Mousavi, Mojtaba, Hossein Balam, Marzieh, Salesi, Mansour

“…Signal transducer and activator of transcription 3 (STAT3) has been introduced as one of the critical genetic factors in the pathogenesis of rheumatoid…”
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Single Nucleotide Polymorphism rs6445975 in the PXK Gene Is Correlated with Susceptibility and Clinical Characteristics of Systemic Lupus Erythematosus by Karimifar, Mansour, Sereshti, Nafiseh, Salehi, Rasoul, Mousavi, Maryam, Karimzadeh, Hadi, Salehi, Amirhossein, Pakzad, Bahram

“…Background: Recently, genome-wide association studies (GWAS) have discovered several single nucleotide polymorphisms (SNPs) and loci associated with the risk…”
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Evaluation of the Association between Antiphospholipid Antibodies and ICU Admission Outcome in Critically Ill COVID-19 Patients in Iranian Population by Pakzad, Bahram, Salehi, Marzieh, Abbasi, Saeed, Salehi, Mohammad Mahdi, Naeini, Maryam Kazemi, Salehi, Hassan

“…The role of anti-phospholipid antibodies (aPLs) in the prognosis of COVID-19 patients is controversial. In order to prove the role of this factor, the…”
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Investigation of rs531564 Polymorphism in the Primary MicroRNA-124 Gene in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis: Association with Disease Susceptibility and Clinical Characteristics by Hassani, Mehdi, Dehani, Mohammad, Zare Rafie, Maryam, Esmaeilzadeh, Emran, Davar, Saeideh, Pakzad, Bahram, Mosallaei, Meysam, Hoseini, Seyyed Mohamad, Bayat, Hadi, Soosanabadi, Mohsen

“…MicroRNA-124 (miR-124) is known as an important regulator of the immune system and inflammatory response. Studies have reported that this miRNA is dysregulated…”
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Association of Three Functional Polymorphisms in the NLRP3 Gene with Susceptibility to Rheumatoid Arthritis in the Iranian Population by Nasrollahzadeh Sabet, Mehrdad, Nasrabadi, Navid, Jalili, Zahra, Pakzad, Bahram, Davar, Saeideh, Ehtesham, Naeim, Jafarpour, Sima, Mosallaei, Meysam, Esmaeilzadeh, Emran

“…Rheumatoid arthritis (RA) is a complex systemic autoimmune disorder with multifactorial nature. Numerous previous studies have shown that several genes are…”
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Interferon-induced protein 44-like gene promoter is differentially methylated in peripheral blood mononuclear cells of systemic lupus erythematosus patients by Karimifar, Mansour, Pakzad, Bahram, Karimzadeh, Hadi, Mousavi, Maryam, Kazemi, Mehdi, Salehi, Amirhossein, Vatandoust, Nasimeh, Amini, Guilda, Akbari, Mojtaba, Salehi, Rasoul

“…Background: The objectives of this study were to compare the interferon-induced protein 44-like (IFI44L) promoter methylation level between systemic lupus…”
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