Search Results - "Bahr, Amber"

Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer by Chan, Joseph M., Quintanal-Villalonga, Álvaro, Gao, Vianne Ran, Xie, Yubin, Allaj, Viola, Chaudhary, Ojasvi, Masilionis, Ignas, Egger, Jacklynn, Chow, Andrew, Walle, Thomas, Mattar, Marissa, Yarlagadda, Dig V.K., Wang, James L., Uddin, Fathema, Offin, Michael, Ciampricotti, Metamia, Qeriqi, Besnik, Bahr, Amber, de Stanchina, Elisa, Bhanot, Umesh K., Lai, W. Victoria, Bott, Matthew J., Jones, David R., Ruiz, Arvin, Baine, Marina K., Li, Yanyun, Rekhtman, Natasha, Poirier, John T., Nawy, Tal, Sen, Triparna, Mazutis, Linas, Hollmann, Travis J., Pe'er, Dana, Rudin, Charles M.

“…Small cell lung cancer (SCLC) is an aggressive malignancy that includes subtypes defined by differential expression of ASCL1, NEUROD1, and POU2F3 (SCLC-A, -N,…”
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Analysis of capecitabine metabolites in conjunction with digital autoradiography in a murine model of pancreatic cancer suggests extensive drug penetration through the tumor by Russell, James, Fanchon, Louise, Alwaseem, Hanan, Molina, Henrik, O’Donoghue, Isabella, Bahr, Amber, Stanchina, Elisa, Pillarsetty, Nagavarakishore, Humm, John L.

“…Previously published digital autoradiography of 3H‐labeled capecitabine reveals a near‐uniform distribution of activity throughout a murine pancreatic model…”
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Type I and II interferons induce granulopoiesis and correlate with organ damage during infection-induced shock by Bahr, Amber, Howard, Jennifer, MacNamara, Kate C.

“…Abstract The mechanisms that drive pathology in infection-induced shock are not well understood. The tick-borne pathogen Ixodes ovatuserhlichia (IOE) induces…”
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Diverse alterations associated with resistance to KRAS(G12C) inhibition by Zhao, Yulei, Murciano-Goroff, Yonina R., Xue, Jenny Y., Ang, Agnes, Lucas, Jessica, Mai, Trang T., Da Cruz Paula, Arnaud F., Saiki, Anne Y., Mohn, Deanna, Achanta, Pragathi, Sisk, Ann E., Arora, Kanika S., Roy, Rohan S., Kim, Dongsung, Li, Chuanchuan, Lim, Lee P., Li, Mark, Bahr, Amber, Loomis, Brian R., de Stanchina, Elisa, Reis-Filho, Jorge S., Weigelt, Britta, Berger, Michael, Riely, Gregory, Arbour, Kathryn C., Lipford, J. Russell, Li, Bob T., Lito, Piro

“…Inactive state-selective KRAS(G12C) inhibitors 1 – 8 demonstrate a 30–40% response rate and result in approximately 6-month median progression-free survival in…”
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Survivors of polymicrobial sepsis are refractory to G-CSF-induced emergency myelopoiesis and hematopoietic stem and progenitor cell mobilization by Biswas, Nirupam, Bahr, Amber, Howard, Jennifer, Bonin, Jesse L., Grazda, Rachel, MacNamara, Katherine C.

“…Sepsis survivors exhibit immune dysfunction, hematological changes, and increased risk of infection. The long-term impacts of sepsis on hematopoiesis were…”
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Predicting Gemcitabine Delivery by 18F-FAC PET in Murine Models of Pancreatic Cancer by Russell, James, Grkovski, Milan, O'Donoghue, Isabella J, Kalidindi, Teja M, Pillarsetty, Nagavarakishore, Burnazi, Eva M, Kulick, Amanda, Bahr, Amber, Chang, Qing, LeKaye, H Carl, de Stanchina, Elisa, Yu, Kenneth H, Humm, John L

“…18F-FAC (2′-deoxy-2′-18F-fluoro-β-d-arabinofuranosylcytosine) has close structural similarity to gemcitabine and thus offers the potential to image drug…”
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Predicting Gemcitabine Delivery by 18 F-FAC PET in Murine Models of Pancreatic Cancer by Russell, James, Grkovski, Milan, O'Donoghue, Isabella J, Kalidindi, Teja M, Pillarsetty, Nagavarakishore, Burnazi, Eva M, Kulick, Amanda, Bahr, Amber, Chang, Qing, LeKaye, H Carl, de Stanchina, Elisa, Yu, Kenneth H, Humm, John L

“…F-FAC (2'-deoxy-2'- F-fluoro-β-d-arabinofuranosylcytosine) has close structural similarity to gemcitabine and thus offers the potential to image drug delivery…”
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Concurrent SOS1 and MEK suppression inhibits signaling and growth of NF1-null melanoma by Marasco, Michelangelo, Kumar, Dinesh, Seale, Tessa, Borrego, Santiago Garcia, Kaplun, Esther, Aricescu, Ilinca, Cole, Soren, Qeriqi, Besnik, Qiu, Juan, Chen, Xiaoping, Bahr, Amber, Fidele, Deborah, Hofmann, Marco H., Gerlach, Daniel, Savarese, Fabio, Merghoub, Taha, Wolchok, Jedd D., Yao, Zhan, de Stanchina, Elisa, Solit, David, Misale, Sandra, Rosen, Neal

“…Neurofibromin (NF1) is a negative regulator of RAS signaling, frequently mutated in cancer. NF1-mutant melanoma is a highly malignant tumor for which targeted…”
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