Search Results - "Bahner, I"

Transduction of human CD34+ hematopoietic progenitor cells by a retroviral vector expressing an RRE decoy inhibits human immunodeficiency virus type 1 replication in myelomonocytic cells produced in long-term culture by Bahner, I, Kearns, K, Hao, Q L, Smogorzewska, E M, Kohn, D B

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Mitogen-independent DNA synthesis by fetal rat hepatocytes in primary culture by Curran, Jr, T R, Bahner, Jr, R I, Oh, W, Gruppuso, P A

“…We have identified conditions under which late gestation fetal rat hepatocytes in primary culture proliferate in the absence of serum, polypeptide growth…”
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Comparison of trans-dominant inhibitory mutant human immunodeficiency virus type 1 genes expressed by retroviral vectors in human T lymphocytes by Bahner, I, Zhou, C, Yu, X J, Hao, Q L, Guatelli, J C, Kohn, D B

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Expression of the genome of potato leafroll virus: readthrough of the coat protein termination codon in vivo by Bahner, I, Lamb, J, Mayo, M. A, Hay, R. T

“…1 Department of Biochemistry and Microbiology, University of St Andrews, Irvine Building, North Street, St Andrews, Fife KY16 9AL and 2 Scottish Crop Research…”
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Inhibition of HIV-1 in human T-lymphocytes by retrovirally transduced anti-tat and rev hammerhead ribozymes by Zhou, C, Bahner, I C, Larson, G P, Zaia, J A, Rossi, J J, Kohn, E B

“…Gene therapy for AIDS requires the identification of genes which effectively inhibit HIV-1 replication coupled to an efficient vector system for gene delivery…”
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Gene transfer into human umbilical cord blood-derived CD34+cells by particle-mediated gene transfer by VERMA, S, WOFFENDIN, C, BAHNER, I, RANGA, U, XU, L, YANG, Z.-Y, KING, S. R, KOHN, D. B, NABEL, G. J

“…Delivery of genes into hematopoietic progenitor cells offers an attractive means for the introduction of corrective or protective genes into cells of both the…”
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Ribozyme-Mediated Inhibition of HIV 1 Suggests Nucleolar Trafficking of HIV-1 RNA by Michienzi, Alessandro, Cagnon, Laurence, Bahner, Ingrid, Rossi, John J.

“…The HIV regulatory proteins Tat and Rev have a nucleolar localization property in human cells. However, no functional role has been attributed to this…”
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A clinical trial of retroviral-mediated transfer of a rev-responsive element decoy gene into CD34+ cells from the bone marrow of human immunodeficiency virus-1-infected children by KOHN, D. B, BAUER, G, BRODY, K, FOX, S, HADEN, E, WILSON, K, SALATA, C, DOLAN, C, WETTER, C, AGUILAR-CORDOVA, E, CHURCH, J, RICE, C. R, ROTHSCHILD, J. C, CARBONARO, D. A, VALDEZ, P, HAO, Q.-L, CHEN ZHOU, BAHNER, I, KEARNS, K

“…Genetic modification of hematopoietic stem cells with genes that inhibit replication of human immunodeficiency virus-1 (HIV-1) could lead to development of T…”
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Inhibition of human immunodeficiency virus-1 (HIV-1) replication after transduction of granulocyte colony-stimulating factor-mobilized CD34+ cells from HIV-1-infected donors using retroviral vectors containing anti-HIV-1 genes by BAUER, G, VALDEZ, P, KEARNS, K, BAHNER, I, SUI FANG WEN, ZAIA, J. A, KOHN, D. B

“…Transfer of "anti-HIV-1 genes" into hematopoietic stem cells of human immunodeficiency virus-1 (HIV-1)-infected individuals may be a potent therapeutic…”
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Expression of hammerhead ribozymes by retroviral vectors to inhibit HIV-1 replication: comparison of RNA levels and viral inhibition by Zhou, C, Bahner, I, Rossi, J J, Kohn, D B

“…We have analyzed expression of anti-HIV-1 hammerhead ribozymes in the context of retroviral vectors. To determine optimal vector designs for ribozyme…”
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Infection of human marrow stroma by human immunodeficiency virus-1 (HIV-1) is both required and sufficient for HIV-1-induced hematopoietic suppression in vitro: Demonstration by gene modification of primary human stroma by BAHNER, I, KEARNS, K, COUTINHO, S, LEONARD, E. H, KOHN, D. B

“…Patients with human immunodeficiency virus-1 (HIV-1) infection often present with bone marrow (BM) failure that may affect all hematopoietic lineages. It is…”
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Structures of Five Components of the Actinomycin Z Complex from Streptomyces fradiae, Two of Which Contain 4-Chlorothreonine by Lackner, Helmut, Bahner, Isabel, Shigematsu, Nobuharu, Pannell, Lewis K, Mauger, Anthony B

“…Structure elucidation of five components of the actinomycin Z complex (Z1−Z5) isolated from Streptomyces fradiae is described. The components were separated by…”
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Retroviral-mediated transfer of the human glucocerebrosidase gene into cultured gaucher bone marrow by NOLTA, J. A, XIAO JIN YU, BAHNER, I, KOHN, D. B

“…Gaucher disease, a lysosomal glycolipid storage disorder, results from the genetic deficiency of an acidic glucosidase, glucocerebrosidase (GC). The beneficial…”
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Transduction of human CD34 super(+) hematopoietic progenitor cells by a retroviral vector expressing an RRE decoy inhibits human immunodeficiency virus type 1 replication in myelomonocytic cells produced in long-term culture by Bahner, I, Kearns, K, Hao, Qian-Lin, Smogorzewska, E M, Kohn, D B

“…Genetic modification of hematopoietic stem cells with a synthetic "anti-human immunodeficiency virus type 1 (HIV-1) gene" which inhibits replication of HIV-I…”
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Suitability of bone marrow from HIV-1-infected donors for retrovirus-mediated gene transfer by Kearns, K, Bahner, I, Bauer, G, Wei, S F, Valdez, P, Wheeler, S, Woods, L, Miller, R, Casciato, D, Galpin, J, Church, J, Kohn, D B

“…Bone marrow samples from 21 human immunodeficiency virus type 1 (HIV-1)-infected subjects were evaluated for their suitability for retrovirus-mediated gene…”
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Gene transfer into human umbilical cord blood-derived CD34 super(+) cells by particle-mediated gene transfer by Verma, S, Woffendin, C, Bahner, I, Ranga, U, Xu, L, Yang, Z-Y, King, SR, Kohn, D B, Nabel, G J

“…Delivery of genes into hematopoietic progenitor cells offers an attractive means for the introduction of corrective or protective genes into cells of both the…”
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Toward gene therapy for Gaucher disease by Kohn, D B, Nolta, J A, Weinthal, J, Bahner, I, Yu, X J, Lilley, J, Crooks, G M

“…We are studying the transfer and expression by retroviral vectors of the human glucocerebrosidase (GC) gene into bone marrow cells as a model of gene therapy…”
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Two different genes coding for processable and nonprocessable forms of a viral envelope protein can account for the apparent hormonal stimulation of protein processing in W7MG1 lymphoma cells by Bedgood, R M, Bahner, I, Kohn, D B, Stallcup, M R

“…In the mouse mammary tumor virus (MMTV)-infected mouse T-lymphoma cell line W7MG1, glucocorticoid hormone regulates two aspects of MMTV gene expression:…”
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