Search Results - "Bahl, Aileen"
-
1
An in-depth multi-omics analysis in RLE-6TN rat alveolar epithelial cells allows for nanomaterial categorization
Published in Particle and fibre toxicology (25-10-2019)“…Abstract Background Nanomaterials (NMs) can be fine-tuned in their properties resulting in a high number of variants, each requiring a thorough safety…”
Get full text
Journal Article -
2
PROTEOMAS: a workflow enabling harmonized proteomic meta-analysis and proteomic signature mapping
Published in Journal of cheminformatics (19-03-2023)“…Toxicological evaluation of substances in regulation still often relies on animal experiments. Understanding the substances’ mode-of-action is crucial to…”
Get full text
Journal Article -
3
Meta‐Analysis of Integrated Proteomic and Transcriptomic Data Discerns Structure–Activity Relationship of Carbon Materials with Different Morphologies
Published in Advanced science (01-03-2024)“…The Fiber Pathogenicity Paradigm (FPP) establishes connections between fiber structure, durability, and disease‐causing potential observed in materials like…”
Get full text
Journal Article -
4
Towards characterization of cell culture conditions for reliable proteomic analysis: in vitro studies on A549, differentiated THP-1, and NR8383 cell lines
Published in Archives of toxicology (01-12-2024)“…Proteomic investigations result in high dimensional datasets, but integration or comparison of different studies is hampered by high variances due to different…”
Get full text
Journal Article -
5
Nanomaterial categorization by surface reactivity: A case study comparing 35 materials with four different test methods
Published in NanoImpact (01-07-2020)“…Nanomaterials (NMs) can be manufactured in plenty of variants differing in their physicochemical properties. Functional assays can be highly useful to cope…”
Get full text
Journal Article -
6
Recursive feature elimination in random forest classification supports nanomaterial grouping
Published in NanoImpact (01-03-2019)“…Nanomaterials (NMs) can be produced in numerous different variants of the same chemical substance. An in-depth safety assessment for each variant by generating…”
Get full text
Journal Article -
7
A computational view on nanomaterial intrinsic and extrinsic features for nanosafety and sustainability
Published in Materials today (Kidlington, England) (01-07-2023)“…[Display omitted] In recent years, an increasing number of diverse Engineered Nano-Materials (ENMs), such as nanoparticles and nanotubes, have been included in…”
Get full text
Journal Article -
8
Bioinformatics and machine learning to support nanomaterial grouping
Published in Nanotoxicology (2024)“…Nanomaterials (NMs) offer plenty of novel functionalities. Moreover, their physicochemical properties can be fine-tuned to meet the needs of specific…”
Get full text
Journal Article -
9
Genome-wide association analysis on normal hearing function identifies PCDH20 and SLC28A3 as candidates for hearing function and loss
Published in Human molecular genetics (01-10-2015)“…Hearing loss and individual differences in normal hearing both have a substantial genetic basis. Although many new genes contributing to deafness have been…”
Get full text
Journal Article -
10
Metabolomics profiling to investigate nanomaterial toxicity in vitro and in vivo
Published in Nanotoxicology (02-07-2020)“…Nanomaterials (NMs) can be produced in plenty of variants posing several challenges for NM hazard and risk assessment. Metabolomic profiling of NM-treated…”
Get full text
Journal Article -
11
Hormone Replacement Therapy Associated White Blood Cell DNA Methylation and Gene Expression are Associated With Within-Pair Differences of Body Adiposity and Bone Mass
Published in Twin research and human genetics (01-12-2015)“…The loss of estrogen during menopause causes changes in the female body, with wide-ranging effects on health. Estrogen-containing hormone replacement therapy…”
Get full text
Journal Article -
12
Metabolomics profiling to investigate nanomaterial toxicity in vitro and in vivo
Published in Nanotoxicology (25-05-2020)“…Nanomaterials (NMs) can be produced in plenty of variants posing several challenges for NM hazard and risk assessment. Metabolomic profiling of NM-treated…”
Get full text
Journal Article