Search Results - "Bahia, Maria Terezinha"
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1
Effects of Ravuconazole Treatment on Parasite Load and Immune Response in Dogs Experimentally Infected with Trypanosoma cruzi
Published in Antimicrobial Agents and Chemotherapy (01-07-2010)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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2
Pharmacological Characterization, Structural Studies, and In Vivo Activities of Anti-Chagas Disease Lead Compounds Derived from Tipifarnib
Published in Antimicrobial Agents and Chemotherapy (01-09-2012)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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3
Real-time PCR strategy for parasite quantification in blood and tissue samples of experimental Trypanosoma cruzi infection
Published in Acta tropica (01-09-2012)“…[Display omitted] ► Real-time PCR is a tool for monitoring parasite load in experimental Trypanosoma cruzi infections. ► Curves of parasitemia were generated…”
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4
Myenteric plexus is differentially affected by infection with distinct Trypanosoma cruzi strains in Beagle dogs
Published in Memórias do Instituto Oswaldo Cruz (01-02-2014)“…Chagasic megaoesophagus and megacolon are characterised by motor abnormalities related to enteric nervous system lesions and their development seems to be…”
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5
Fexinidazole: a potential new drug candidate for Chagas disease
Published in PLoS neglected tropical diseases (01-11-2012)“…New safe and effective treatments for Chagas disease (CD) are urgently needed. Current chemotherapy options for CD have significant limitations, including…”
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6
In vitro and in vivo experimental models for drug screening and development for Chagas disease
Published in Memórias do Instituto Oswaldo Cruz (01-03-2010)“…Chagas disease, a neglected illness, affects nearly 12-14 million people in endemic areas of Latin America. Although the occurrence of acute cases sharply has…”
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7
Profile of interstitial cells of Cajal in a murine model of chagasic megacolon
Published in Anais da Academia Brasileira de Ciências (01-01-2024)“…Disorders of gastrointestinal motility are the major physiologic problem in chagasic megacolon. The contraction mechanism is complex and controlled by…”
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8
Benznidazole and posaconazole in experimental Chagas disease: positive interaction in concomitant and sequential treatments
Published in PLoS neglected tropical diseases (01-08-2013)“…Current chemotherapy for Chagas disease is unsatisfactory due to its limited efficacy, particularly in the chronic phase, with frequent side effects that can…”
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9
Benznidazole/Itraconazole Combination Treatment Enhances Anti-Trypanosoma cruzi Activity in Experimental Chagas Disease
Published in PloS one (15-06-2015)“…The nitroheterocyclic drugs nifurtimox and benznidazole are first-line drugs available to treat Chagas disease; however, they have limitations, including long…”
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10
Trypanosoma cruzi antigen detection in blood to assess treatment efficacy and cure in mice models of Chagas disease
Published in Frontiers in immunology (2023)“…Chagas disease (CD) is caused by the protozoan parasite . Although endemic mainly in Latin America, CD has become a global public health problem due to…”
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11
Poly-ε-Caprolactone Implants for Benznidazole Prolonged Release: An Alternative to Chagas Disease Oral Treatment
Published in Pharmaceutics (01-04-2023)“…Benznidazole (BZ) tablets are the currently prescribed treatment for Chagas disease. However, BZ presents limited efficacy and a prolonged treatment regimen…”
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12
Neuronal Parasitism, Early Myenteric Neurons Depopulation and Continuous Axonal Networking Damage as Underlying Mechanisms of the Experimental Intestinal Chagas' Disease
Published in Frontiers in cellular and infection microbiology (15-10-2020)“…There is a growing consensus that the balance between the persistence of infection and the host immune response is crucial for chronification of Chagas heart…”
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13
Profile of natural Trypanosoma cruzi infection among dogs from rural areas of southern Espírito Santo, Brazil
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2022)“…The emergence of Trypanosoma cruzi infection via oral transmission has a habitual character in its primitive endemic cycle. Recent findings revealed the first…”
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14
Leishmania infantum-derived lipophosphoglycan as an antigen in the accurate serodiagnosis of canine leishmaniasis
Published in PLoS neglected tropical diseases (01-09-2019)“…Lipophosphoglycan (LPG) is the major surface glycoconjugate of Leishmania protozoan and has an important biological role in host-parasite interactions both in…”
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15
A comparative study of the TF-Test®, Kato-Katz, Hoffman-Pons-Janer, Willis and Baermann-Moraes coprologic methods for the detection of human parasitosis
Published in Memórias do Instituto Oswaldo Cruz (01-02-2012)“…This study compares the diagnostic accuracy of the TF-Test® (TFT) for human parasitosis with results obtained using the traditional Kato-Katz (KK),…”
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Correction: Enteric Neuronal Damage, Intramuscular Denervation and Smooth Muscle Phenotype Changes as Mechanisms of Chagasic Megacolon: Evidence from a Long-Term Murine Model of Tripanosoma cruzi Infection
Published in PloS one (17-04-2017)“…[This corrects the article DOI: 10.1371/journal.pone.0153038.]…”
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Benznidazole therapy during acute phase of Chagas disease reduces parasite load but does not prevent chronic cardiac lesions
Published in Parasitology research (1987) (01-07-2008)“…The goals of this study were to evaluate the efficacy of benznidazole (Bz) treatment in decreasing of the parasitic load during the acute phase of experimental…”
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18
Mir-190b negatively contributes to the Trypanosoma cruzi-infected cell survival by repressing PTEN protein expression
Published in Memórias do Instituto Oswaldo Cruz (01-12-2015)“…Chagas disease, which is caused by the intracellular protozoan Trypanosoma cruzi, is a serious health problem in Latin America. The heart is one of the major…”
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19
Enteric Neuronal Damage, Intramuscular Denervation and Smooth Muscle Phenotype Changes as Mechanisms of Chagasic Megacolon: Evidence from a Long-Term Murine Model of Trypanosoma cruzi Infection
Published in PloS one (2016)“…We developed a novel murine model of long-term infection with Trypanosoma cruzi with the aim to elucidate the pathogenesis of megacolon and the associated…”
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20
Cardiomyopathy prognosis after benznidazole treatment in chronic canine Chagas' disease
Published in Journal of antimicrobial chemotherapy (01-08-2012)“…To evaluate the effects of benznidazole on Chagas' disease cardiac prognosis using an experimental dog model of infection. A total of 28 dogs were divided into…”
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