Search Results - "Bago, Ružica"

Subcellular localization of Nm23/NDPK A and B isoforms: a reflection of their biological function by Bosnar, Maja Herak, Bago, Ružica, Ćetković, Helena

“…The family of Nm23/NDPK (nucleoside diphosphate kinase) proteins regulates a vast variety of cellular processes and, therefore, participates in important…”
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Sponge non-metastatic Group I Nme gene/protein - structure and function is conserved from sponges to humans by Perina, Drago, Bosnar, Maja Herak, Bago, Ružica, Mikoč, Andreja, Harcet, Matija, Deželjin, Martina, Cetković, Helena

“…Nucleoside diphosphate kinases NDPK are evolutionarily conserved enzymes present in Bacteria, Archaea and Eukarya, with human Nme1 the most studied…”
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Binding to Syntenin-1 Protein Defines a New Mode of Ubiquitin-based Interactions Regulated by Phosphorylation by Rajesh, Sundaresan, Bago, Ružica, Odintsova, Elena, Muratov, Gayrat, Baldwin, Gouri, Sridhar, Pooja, Rajesh, Sandya, Overduin, Michael, Berditchevski, Fedor

“…Syntenin-1 is a PDZ domain-containing adaptor that controls trafficking of transmembrane proteins including those associated with tetraspanin-enriched…”
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Nm23-H1 promotes adhesion of CAL 27 cells in vitro by Bago, Ružica, Pavelić, Jasminka, Vlahoviček, Gordana Maravić, Bosnar, Maja Herak

“…nm23‐H1 was found to diminish metastatic potential of carcinoma cell lines and therefore was placed in the group of metastatic suppressor genes. Its protein…”
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Subcellular localization of A and B Nm23/NDPK subunits by Bosnar, Maja Herak, de Gunzburg, Jean, Bago, Ružica, Brečević, Lukrecija, Weber, Igor, Pavelić, Jasminka

“…The human Nm23-H1/NDPK A and Nm23-H2/NDPK B encode for two subunits of nucleoside diphosphate kinase—a ubiquitous enzyme that transfers the terminal phosphates…”
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The CD63-Syntenin-1 Complex Controls Post-Endocytic Trafficking of Oncogenic Human Papillomaviruses by Gräßel, Linda, Fast, Laura Aline, Scheffer, Konstanze D., Boukhallouk, Fatima, Spoden, Gilles A., Tenzer, Stefan, Boller, Klaus, Bago, Ruzica, Rajesh, Sundaresan, Overduin, Michael, Berditchevski, Fedor, Florin, Luise

“…Human papillomaviruses enter host cells via a clathrin-independent endocytic pathway involving tetraspanin proteins. However, post-endocytic trafficking…”
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Downstream targets of Nm23-H1: Gene expression profiling of CAL 27 cells using DNA microarray by Bosnar, Maja Herak, Bago, Ružica, Gall-Trošelj, Koraljka, Streichert, Thomas, Pavelić, Jasminka

“…The human nm23‐H1 was discovered as a tumor metastasis suppressor based on its reduced expression in melanoma cell lines with low versus high metastatic…”
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Cytogenetic evaluation, fluorescence in situ hybridization, and molecular study of psu idic(X)(pter-->q22.3::q22.3-->pter) chromosome abberation in a girl with moderate growth retardation by Petković, Iskra, Barisić, Ingeborg, Bago, Ruzica

“…Combined cytogenetic, fluorescence in situ hybridization (FISH), and molecular analysis are useful in the diagnosis of sex chromosome aberrations. These…”
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Dictyostelium discoideum nucleoside diphosphate kinase C plays a negative regulatory role in phagocytosis, macropinocytosis and exocytosis by Annesley, Sarah J, Bago, Ruzica, Bosnar, Maja Herak, Filic, Vedrana, Marinović, Maja, Weber, Igor, Mehta, Anil, Fisher, Paul R

“…Nucleoside diphosphate kinases (NDPKs) are ubiquitous phosphotransfer enzymes responsible for producing most of the nucleoside triphosphates except for ATP…”
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The first case of the FRAXE form of inherited mental retardation in Croatia by HECIMOVIC, Silva, BAGO, Ruzica, MUZINIC, Dubravka, BEGOVIC, Davor, PAVELIC, Kresimir

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PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition by Castel, Pau, Ellis, Haley, Bago, Ruzica, Toska, Eneda, Razavi, Pedram, Carmona, F. Javier, Kannan, Srinivasaraghavan, Verma, Chandra S., Dickler, Maura, Chandarlapaty, Sarat, Brogi, Edi, Alessi, Dario R., Baselga, José, Scaltriti, Maurizio

“…PIK3CA, which encodes the p110α subunit of PI3K, is frequently mutated and oncogenic in breast cancer. PI3Kα inhibitors are in clinical development and despite…”
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Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase by Bago, Ruzica, Malik, Nazma, Munson, Michael J, Prescott, Alan R, Davies, Paul, Sommer, Eeva, Shpiro, Natalia, Ward, Richard, Cross, Darren, Ganley, Ian G, Alessi, Dario R

“…The Vps34 (vacuolar protein sorting 34) class III PI3K (phosphoinositide 3-kinase) phosphorylates PtdIns (phosphatidylinositol) at endosomal membranes to…”
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mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer by Zabala-Letona, Amaia, Arruabarrena-Aristorena, Amaia, Martín-Martín, Natalia, Fernandez-Ruiz, Sonia, Sutherland, James D., Clasquin, Michelle, Tomas-Cortazar, Julen, Jimenez, Jose, Torres, Ines, Quang, Phong, Ximenez-Embun, Pilar, Bago, Ruzica, Ugalde-Olano, Aitziber, Loizaga-Iriarte, Ana, Lacasa-Viscasillas, Isabel, Unda, Miguel, Torrano, Verónica, Cabrera, Diana, van Liempd, Sebastiaan M., Cendon, Ylenia, Castro, Elena, Murray, Stuart, Revandkar, Ajinkya, Alimonti, Andrea, Zhang, Yinan, Barnett, Amelia, Lein, Gina, Pirman, David, Cortazar, Ana R., Arreal, Leire, Prudkin, Ludmila, Astobiza, Ianire, Valcarcel-Jimenez, Lorea, Zuñiga-García, Patricia, Fernandez-Dominguez, Itziar, Piva, Marco, Caro-Maldonado, Alfredo, Sánchez-Mosquera, Pilar, Castillo-Martín, Mireia, Serra, Violeta, Beraza, Naiara, Gentilella, Antonio, Thomas, George, Azkargorta, Mikel, Elortza, Felix, Farràs, Rosa, Olmos, David, Efeyan, Alejo, Anguita, Juan, Muñoz, Javier, Falcón-Pérez, Juan M., Barrio, Rosa, Macarulla, Teresa, Mato, Jose M., Martinez-Chantar, Maria L., Cordon-Cardo, Carlos, Aransay, Ana M., Marks, Kevin, Baselga, José, Tabernero, Josep, Nuciforo, Paolo, Manning, Brendan D., Marjon, Katya, Carracedo, Arkaitz

“…mTOR complex 1 signalling regulates polyamine metabolism and thereby promotes tumorigenesis, through regulation of the stability of a key enzyme, AMD1. Cell…”
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The hVps34-SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growth by Bago, Ruzica, Sommer, Eeva, Castel, Pau, Crafter, Claire, Bailey, Fiona P, Shpiro, Natalia, Baselga, José, Cross, Darren, Eyers, Patrick A, Alessi, Dario R

“…We explore mechanisms that enable cancer cells to tolerate PI3K or Akt inhibitors. Prolonged treatment of breast cancer cells with PI3K or Akt inhibitors leads…”
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Paternal origin of der(X)t(X;6) in a girl with trisomy 6p and unbalanced t(6;10) mosaicism in her mother by Petković, Iskra, Barišić, Ingeborg, Bastić, Mislav, Hećimović, Silva, Bago, Ružica

“…We present a case of trisomy for the whole short arm of chromosome 6 in a 3‐year‐old girl with moderate mental retardation, mild facial dysmorphism, short…”
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The hVps34-SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growth by Bago, Ruzica, Sommer, Eeva, Castel, Pau, Crafter, Claire, Bailey, Fiona P, Shpiro, Natalia, Baselga, José, Cross, Darren, Eyers, Patrick A, Alessi, Dario R

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Erratum To: The hVps34‐SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growth by Bago, Ruzica, Sommer, Eeva, Castel, Pau, Crafter, Claire, Bailey, Fiona P, Shpiro, Natalia, Baselga, José, Cross, Darren, Eyers, Patrick A, Alessi, Dario R

“…Graphical Abstract…”
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The hV ps34‐ SGK 3 pathway alleviates sustained PI 3K/Akt inhibition by stimulating mTORC 1 and tumour growth by Bago, Ruzica, Sommer, Eeva, Castel, Pau, Crafter, Claire, Bailey, Fiona P, Shpiro, Natalia, Baselga, José, Cross, Darren, Eyers, Patrick A, Alessi, Dario R

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The hVps34‐ SGK 3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC 1 and tumour growth by Bago, Ruzica, Sommer, Eeva, Castel, Pau, Crafter, Claire, Bailey, Fiona P, Shpiro, Natalia, Baselga, José, Cross, Darren, Eyers, Patrick A, Alessi, Dario R

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Abstract 2107: PDK1 blockade overcomes intrinsic resistance to PI3Kα inhibition by Castel, Pau, Ellis, Haley, Bago, Ruzica, Toska, Eneda, Srinivasaraghavan, Kannan, Carmona, F Javier, Razavi, Pedram, Verma, Chandra, Dickler, Maura, Chandarlapaty, Sarat, Brogi, Edi, Alessi, Dario, Baselga, José, Scaltriti, Maurizio

“…Abstract Somatic mutations in PIK3CA, the gene encoding the α isoform of PI3K (p110α), are frequent in breast cancer. These mutations lead to constitutive…”
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