Search Results - "Bago, R"
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Macrophage-Derived Extracellular Vesicles as Drug Delivery Systems for Triple Negative Breast Cancer (TNBC) Therapy
Published in Journal of neuroimmune pharmacology (01-09-2020)“…Efficient targeted delivery of anticancer agents to TNBC cells remains one of the greatest challenges to developing therapies. The lack of tumor-specific…”
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2
Reactive astrocytes potentiate tumor aggressiveness in a murine glioma resection and recurrence model
Published in Neuro-oncology (Charlottesville, Va.) (01-12-2016)“…Surgical resection is a universal component of glioma therapy. Little is known about the postoperative microenvironment due to limited preclinical models…”
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3
Intercellular Mitochondrial Transfer in the Tumor Microenvironment
Published in Cancers (04-07-2020)“…Cell-to-cell communication is a fundamental process in every multicellular organism. In addition to membrane-bound and released factors, the sharing of…”
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4
Intra-cavity stem cell therapy inhibits tumor progression in a novel murine model of medulloblastoma surgical resection
Published in PloS one (10-07-2018)“…Cytotoxic neural stem cells (NSCs) have emerged as a promising treatment for Medulloblastoma (MB), the most common malignant primary pediatric brain tumor. The…”
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Engineered Mesenchymal Stem Cell/Nanomedicine Spheroid as an Active Drug Delivery Platform for Combinational Glioblastoma Therapy
Published in Nano letters (13-03-2019)“…Mesenchymal stem cell (MSC) has been increasingly applied to cancer therapy because of its tumor-tropic capability. However, short retention at target tissue…”
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Therapeutically engineered induced neural stem cells are tumour-homing and inhibit progression of glioblastoma
Published in Nature communications (02-02-2016)“…Transdifferentiation (TD) is a recent advancement in somatic cell reprogramming. The direct conversion of TD eliminates the pluripotent intermediate state to…”
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Tumor-homing cytotoxic human induced neural stem cells for cancer therapy
Published in Science translational medicine (01-02-2017)“…Engineered neural stem cells (NSCs) are a promising approach to treating glioblastoma (GBM). The ideal NSC drug carrier for clinical use should be easily…”
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Electrospun nanofibrous scaffolds increase the efficacy of stem cell-mediated therapy of surgically resected glioblastoma
Published in Biomaterials (01-06-2016)“…Abstract Engineered stem cell (SC)-based therapy holds enormous promise for treating the incurable brain cancer glioblastoma (GBM). Retaining the cytotoxic SCs…”
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9
Fibrin matrices enhance the transplant and efficacy of cytotoxic stem cell therapy for post-surgical cancer
Published in Biomaterials (01-04-2016)“…Abstract Tumor-homing cytotoxic stem cell (SC) therapy is a promising new approach for treating the incurable brain cancer glioblastoma (GBM). However,…”
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10
Preclinical scenario of targeting myocardial fibrosis with chimeric antigen receptor (CAR) immunotherapy
Published in Biomedicine & pharmacotherapy (01-02-2023)“…Fibrosis is present in an important proportion of myocardial disorders. Injury activates cardiac fibroblasts, which deposit excess extracellular matrix,…”
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11
NK92 Expressing Anti-BCMA CAR and Secreted TRAIL for the Treatment of Multiple Myeloma: Preliminary In Vitro Assessment
Published in Cells (Basel, Switzerland) (30-11-2023)“…Multiple myeloma (MM) has witnessed improved patient outcomes through advancements in therapeutic approaches. Notably, allogeneic stem cell transplantation,…”
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Cytotoxic Engineered Induced Neural Stem Cells as an Intravenous Therapy for Primary Non-Small Cell Lung Cancer and Triple-Negative Breast Cancer
Published in Molecular cancer therapeutics (01-11-2021)“…Converting human fibroblasts into personalized induced neural stem cells (hiNSC) that actively seek out tumors and deliver cytotoxic agents is a promising…”
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13
Human umbilical cord blood-derived mesenchymal stem cells promote vascular growth in vivo
Published in PloS one (16-11-2012)“…Stem cell therapies are promising strategies to regenerate human injured tissues, including ischemic myocardium. Here, we examined the acquisition of…”
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14
A bird's-eye view of cell therapy and tissue engineering for cardiac regeneration
Published in Annals of the New York Academy of Sciences (01-04-2012)“…Complete recovery of ischemic cardiac muscle after myocardial infarction is still an unresolved concern. In recent years, intensive research efforts have…”
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15
Generation and Profiling of Tumor-Homing Induced Neural Stem Cells from the Skin of Cancer Patients
Published in Molecular therapy (08-07-2020)“…The conversion of human fibroblasts into personalized induced neural stem cells (iNSCs) that actively seek out tumors and deliver cytotoxic agents is a highly…”
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Glioblastoma therapy with cytotoxic mesenchymal stromal cells optimized by bioluminescence imaging of tumor and therapeutic cell response
Published in PloS one (17-04-2012)“…Genetically modified adipose tissue derived mesenchymal stromal cells (hAMSCs) with tumor homing capacity have been proposed for localized therapy of chemo-…”
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17
Activation of mitogen- and stress-activated kinase 1 is required for proliferation of breast cancer cells in response to estrogens or progestins
Published in Oncogene (20-03-2014)“…Growth of breast cancers is often dependent on ovarian steroid hormones making the tumors responsive to antagonists of hormone receptors. However, eventually…”
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Bioluminescence imaging of cardiomyogenic and vascular differentiation of cardiac and subcutaneous adipose tissue-derived progenitor cells in fibrin patches in a myocardium infarct model
Published in International journal of cardiology (15-11-2013)“…Abstract Background Adipose tissue-derived progenitor cells (ATDPCs) isolated from human cardiac adipose tissue are useful for cardiac regeneration in rodent…”
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Gene expression profiling of Nm23-H2 overexpressing CAL 27 cells using DNA microarray
Published in Neoplasma (2008)“…Nm23-H1/NDPKA and Nm23-H2/NDPKB belong to a large family of NDP kinases, group of structurally and functionally closely related enzymes. The Nm23/NDPs are…”
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Novel Local "Off-the-Shelf" Immunotherapy for the Treatment of Myeloma Bone Disease
Published in Cells (Basel, Switzerland) (30-01-2023)“…Myeloma bone disease (MBD) is one of the major complications in multiple myeloma (MM)-the second most frequent hematologic malignancy. It is characterized by…”
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