Search Results - "Bagnall, J"

Enantiomeric profiling of a chemically diverse mixture of chiral pharmaceuticals in urban water by Evans, S., Bagnall, J., Kasprzyk-Hordern, B.

“…Due to concerns regarding the release of pharmaceuticals into the environment and the understudied impact of stereochemistry of pharmaceuticals on their fate…”
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Inflammasome-dependent IL-1β release depends upon membrane permeabilisation by Martín-Sánchez, F, Diamond, C, Zeitler, M, Gomez, A I, Baroja-Mazo, A, Bagnall, J, Spiller, D, White, M, Daniels, M J D, Mortellaro, A, Peñalver, M, Paszek, P, Steringer, J P, Nickel, W, Brough, D, Pelegrín, P

“…Interleukin-1 β (IL-1 β ) is a critical regulator of the inflammatory response. IL-1 β is not secreted through the conventional ER–Golgi route of protein…”
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Development and Validation of a Combined Hypoxia and Immune Prognostic Classifier for Head and Neck Cancer by Brooks, Jill M, Menezes, Albert N, Ibrahim, Maha, Archer, Lucinda, Lal, Neeraj, Bagnall, Christopher J, von Zeidler, Sandra V, Valentine, Helen R, Spruce, Rachel J, Batis, Nikolaos, Bryant, Jennifer L, Hartley, Margaret, Kaul, Baksho, Ryan, Gordon B, Bao, Riyue, Khattri, Arun, Lee, Steven P, Ogbureke, Kalu U E, Middleton, Gary, Tennant, Daniel A, Beggs, Andrew D, Deeks, Jonathan, West, Catharine M L, Cazier, Jean-Baptiste, Willcox, Benjamin E, Seiwert, Tanguy Y, Mehanna, Hisham

“…Intratumoral hypoxia and immunity have been correlated with patient outcome in various tumor settings. However, these factors are not currently considered for…”
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MADS Box Genes Control Vernalization-Induced Flowering in Cereals by Trevaskis, Ben, Bagnall, David J., Ellis, Marc H., Peacock, W. James, Dennis, Elizabeth S.

“…By comparing expression levels of MADS box transcription factor genes between near-isogenic winter and spring lines of bread wheat, Triticum aestivum, we have…”
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Using chiral liquid chromatography quadrupole time-of-flight mass spectrometry for the analysis of pharmaceuticals and illicit drugs in surface and wastewater at the enantiomeric level by Bagnall, J.P., Evans, S.E., Wort, M.T., Lubben, A.T., Kasprzyk-Hordern, B.

“…► Here two chiral LC–QTOF-MS methods are detailed for the analysis of pharmaceuticals and illicit drugs. ► Methods are suitable for resolving and quantifying…”
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Anti‐inflammatory effects of infliximab in mice are independent of tumour necrosis factor α neutralization by Assas, B. M., Levison, S. E., Little, M., England, H., Battrick, L., Bagnall, J., McLaughlin, J. T., Paszek, P., Else, K. J., Pennock, J. L.

“…Summary Infliximab (IFX) has been used repeatedly in mouse preclinical models with associated claims that anti‐inflammatory effects are due to inhibition of…”
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The endothelin system as a therapeutic target in cardiovascular disease: great expectations or bleak house? by Kirkby, N S, Hadoke, P W F, Bagnall, A J, Webb, D J

“…There is considerable evidence that the potent vasoconstrictor endothelin‐1 (ET‐1) contributes to the pathogenesis of a variety of cardiovascular diseases. As…”
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1-Year Follow-Up Optical Frequency Domain Imaging of Multiple Bioresorbable Vascular Scaffolds for the Treatment of Spontaneous Coronary Artery Dissection by Watt, Jonathan, MB, ChB, MD, Egred, Mohaned, MB, ChB, MD, Khurana, Ayush, MB, ChB, Bagnall, Alan J., MB, ChB, PhD, Zaman, Azfar G., MB, ChB, MD

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Differential sub-nuclear distribution of hypoxia-inducible factors (HIF)-1 and -2 alpha impacts on their stability and mobility by Taylor, S. E., Bagnall, J., Mason, D., Levy, R., Fernig, D. G., See, V.

“…Cellular adaptation to hypoxia occurs via a complex programme of gene expression mediated by the hypoxia-inducible factor (HIF). The oxygen labile alpha…”
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Symbiotic effectiveness of rhizobial mutualists varies in interactions with native Australian legume genera by Thrall, Peter H, Laine, Anna-Liisa, Broadhurst, Linda M, Bagnall, David J, Brockwell, John

“…Interactions between plants and beneficial soil organisms (e.g. rhizobial bacteria, mycorrhizal fungi) are models for investigating the ecological impacts of…”
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Hot or Not? Reassessing Mechanisms of Photocurrent Generation in Plasmon‐Enhanced Electrocatalysis by Bagnall, Andrew J., Ganguli, Sagar, Sekretareva, Alina

“…It is now widely accepted that certain effects arising from localised surface plasmon resonance, such as enhanced electromagnetic fields, hot carriers, and…”
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GAMYB-like Genes, Flowering, and Gibberellin Signaling in Arabidopsis by Gregory F. W. Gocal, Sheldon, Candice C., Gubler, Frank, Moritz, Thomas, Bagnall, David J., Colleen P. Mac Millan, Song F. Li, Parish, Roger W., Dennis, Elizabeth S., Weigel, Detlef, Rod W. King

“…We have identified three Arabidopsis genes with GAMYB-like activity, AtMYB33, AtMYB65, and AtMYB101, which can substitute for barley (Hordeum vulgare) GAMYB in…”
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Quantitative dynamic imaging of immune cell signalling using lentiviral gene transfer by Bagnall, J, Boddington, C, Boyd, J, Brignall, R, Rowe, W, Jones, N A, Schmidt, L, Spiller, D G, White, M R H, Paszek, P

“…Live-cell imaging of fluorescent fusion proteins has transformed our understanding of mammalian cell signalling and function. However, some cellular systems…”
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Temporal management patterns and outcomes of non-ST elevation acute coronary syndromes in patients with kidney dysfunction by Wong, Jorge A., Goodman, Shaun G., Yan, Raymond T., Wald, Ron, Bagnall, Alan J., Welsh, Robert C., Wong, Graham C., Kornder, Jan, Eagle, Kim A., Steg, Philippe Gabriel, Yan, Andrew T.

“…Aims To examine: (i) the temporal changes in the management pattern; (ii) the reasons for any treatment disparities; (iii) the relationship between invasive…”
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Resource dependent biodegradation of estrogens and the role of ammonia oxidising and heterotrophic bacteria by Bagnall, J.P., Ito, A., McAdam, E.J., Soares, A., Lester, J.N., Cartmell, E.

“…► Estrogen biodegradation was achieved using non acclimated biomass within 24h. ► Reductions in ammonia oxidising bacteria did not effect estrogen…”
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Heterogenised Molecular Catalysts for Sustainable Electrochemical CO2 Reduction by Grammatico, Domenico, Bagnall, Andrew J., Riccardi, Ludovico, Fontecave, Marc, Su, Bao‐Lian, Billon, Laurent

“…There has been a rapid rise in interest regarding the advantages of support materials to protect and immobilise molecular catalysts for the carbon dioxide…”
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A multiagent model of the UK market in electricity generation by Bagnall, A.J., Smith, G.D.

“…The deregulation of electricity markets has continued apace around the globe. The best structure for deregulated markets is a subject of much debate, and the…”
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Non-endothelial cell endothelin-B receptors limit neointima formation following vascular injury by KIRKBY, Nicholas S, DUTHIE, Karolina M, MILLER, Eileen, KOTELEVTSEV, Yuri V, BAGNALL, Alan J, WEBB, David J, HADOKE, Patrick W. F

“…The potent vasoconstrictor endothelin-1 (ET-1), acting on the endothelin-A (ETA) receptor, promotes intimal lesion formation following vascular injury. The…”
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Influence of Age on Use of Cardiac Catheterization and Associated Outcomes in Patients With Non-ST-Elevation Acute Coronary Syndromes by Bagnall, Alan J., MB, ChB, PhD, Goodman, Shaun G., MD, MSc, Fox, Keith A.A., MB, ChB, Yan, Raymond T., MD, MASc, Gore, Joel M., MD, Cheema, Asim N., MD, PhD, Huynh, Thao, MD, Chauret, Denis, MD, Fitchett, David H., MD, Langer, Anatoly, MD, MSc, Yan, Andrew T., MD

“…Randomized controlled trials support the use of an early invasive strategy in high-risk patients with non-ST-segment elevation (NSTE) acute coronary syndromes…”
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Treatment and Outcomes of Patients With Suspected Acute Coronary Syndromes in Relation to Initial Diagnostic Impressions (Insights from the Canadian Global Registry of Acute Coronary Events [GRACE] and Canadian Registry of Acute Coronary Events [CANRACE]) by Bajaj, Ravi R., MD, Goodman, Shaun G., MD, MSc, Yan, Raymond T., MD, Bagnall, Alan J., MRCP, BSc, PhD, Gyenes, Gabor, MD, Welsh, Robert C., MD, Eagle, Kim A., MD, Brieger, David, MBBS, PhD, Ramanathan, Krishnan, MD, Grondin, Francois R., MD, Yan, Andrew T., MD

“…The early diagnosis of acute coronary syndrome (ACS) remains challenging, and a considerable proportion of patients are diagnosed with “possible” ACS on…”
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