Search Results - "Bagley, Kenneth C"

Induction of food-specific IgG by Gene Gun-delivered DNA vaccines by Smeekens, Johanna M., Kesselring, Janelle R., Frizzell, Hannah, Bagley, Kenneth C., Kulis, Michael D.

“…BackgroundShellfish and tree nut allergies are among the most prevalent food allergies, now affecting 2%-3% and 1% of the US population, respectively…”
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A Gut Reaction to SIV and SHIV Infection: Lower Dysregulation of Mucosal T Cells during Acute Infection Is Associated with Greater Viral Suppression during cART by O'Connor, Megan A, Munson, Paul V, Dross, Sandra E, Tunggal, Hillary C, Lewis, Thomas B, Osborn, Jessica, Peterson, Christopher W, Huang, Meei-Li W, Moats, Cassandra, Smedley, Jeremy, Jerome, Keith R, Kiem, Hans-Peter, Bagley, Kenneth C, Mullins, James I, Fuller, Deborah Heydenburg

“…Selection of a pre-clinical non-human primate (NHP) model is essential when evaluating therapeutic vaccine and treatment strategies for HIV. SIV and…”
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Adjuvant Activity of the Catalytic A1 Domain of Cholera Toxin for Retroviral Antigens Delivered by GeneGun by Bagley, Kenneth C, Lewis, George K, Fouts, Timothy R

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Pertussis toxin and the adenylate cyclase toxin from Bordetella pertussis activate human monocyte-derived dendritic cells and dominantly inhibit cytokine production through a cAMP-dependent pathway by Bagley, Kenneth C., Abdelwahab, Sayed F., Tuskan, Robert G., Fouts, Timothy R., Lewis, George K.

“…Pertussis toxin (PT) and adenylate cyclase toxin (AT) are AB enterotoxins produced by Bordetella pertussis. PT is a powerful mucosal adjuvant whose cellular…”
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Cholera Toxin and Heat-Labile Enterotoxin Activate Human Monocyte-Derived Dendritic Cells and Dominantly Inhibit Cytokine Production through a Cyclic AMP-Dependent Pathway by BAGLEY, Kenneth C, ABDELWAHAB, Sayed F, TUSKAN, Robert G, FOUTS, Timothy R, LEWIS, George K

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HIV-1-Suppressive Factors Are Secreted by CD4+T Cells during Primary Immune Responses by Abdelwahab, Sayed F., Cocchi, Fiorenza, Bagley, Kenneth C., Kamin-Lewis, Roberta, Gallo, Robert C., DeVico, Anthony, Lewis, George K.

“…CD4+T cells are required for immunity against many viral infections, including HIV-1 where a positive correlation has been observed between strong recall…”
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Pasteurella multocida Toxin Activates Human Monocyte-Derived and Murine Bone Marrow-Derived Dendritic Cells In Vitro but Suppresses Antibody Production In Vivo by Bagley, Kenneth C, Abdelwahab, Sayed F, Tuskan, Robert G, Lewis, George K

“…Pasteurella multocida toxin (PMT) is a potent mitogen for fibroblasts and osteoblastic cells. PMT activates phospholipase C-[beta] through G[subscript…”
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Calcium signaling through phospholipase C activates dendritic cells to mature and is necessary for the activation and maturation of dendritic cells induced by diverse agonists by Bagley, Kenneth C, Abdelwahab, Sayed F, Tuskan, Robert G, Lewis, George K

“…Calcium is an important second messenger in the phospholipase C (PLC) signal transduction pathway. Calcium signaling is involved in many biological processes,…”
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Mucosal T Helper 17 and T Regulatory Cell Homeostasis Correlate with Acute Simian Immunodeficiency Virus Viremia and Responsiveness to Antiretroviral Therapy in Macaques by O'Connor, Megan A, Munson, Paul V, Tunggal, Hillary C, Hajari, Nika, Lewis, Thomas B, Bratt, Debra, Moats, Cassie, Smedley, Jeremy, Bagley, Kenneth C, Mullins, James I, Fuller, Deborah H

“…Depletion of gut T helper 17 (Th17) cells during HIV infection leads to decreased mucosal integrity and increased disease progression. Conversely, T regulatory…”
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An Interleukin 12 Adjuvanted Herpes Simplex Virus 2 DNA Vaccine Is More Protective Than a Glycoprotein D Subunit Vaccine in a High-Dose Murine Challenge Model by Bagley, Kenneth C, Schwartz, Jennifer A, Andersen, Hanne, Eldridge, John H, Xu, Rong, Ota-Setlik, Ayuko, Geltz, Joshua J, Halford, William P, Fouts, Timothy R

“…Vaccination is a proven intervention against human viral diseases; however, success against Herpes Simplex Virus 2 (HSV-2) remains elusive. Most HSV-2 vaccines…”
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An Enzymatically Active A Domain Is Required for Cholera-Like Enterotoxins To Induce a Long-Lived Blockade on the Induction of Oral Tolerance: New Method for Screening Mucosal Adjuvants by BAGLEY, Kenneth C, ABDELWAHAB, Sayed F, TUSKAN, Robert G, LEWIS, George K

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Cholera Toxin Indirectly Activates Human Monocyte-Derived Dendritic Cells In Vitro through the Production of Soluble Factors, Including Prostaglandin E2 and Nitric Oxide by Bagley, Kenneth C., Abdelwahab, Sayed F., Tuskan, Robert G., Lewis, George K.

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Cholera Toxin Indirectly Activates Human Monocyte-Derived Dendritic Cells In Vitro through the Production of Soluble Factors, Including Prostaglandin E 2 and Nitric Oxide by Bagley, Kenneth C., Abdelwahab, Sayed F., Tuskan, Robert G., Lewis, George K.

“…Cholera toxin (CT) is a potent adjuvant that activates dendritic cells (DC) by increasing intracellular cyclic AMP (cAMP) levels. In vivo and in vitro, very…”
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Cholera toxin indirectly activates human monocyte-derived dendritic cells in vitro through the production of soluble factors, including prostaglandin E(2) and nitric oxide by Bagley, Kenneth C, Abdelwahab, Sayed F, Tuskan, Robert G, Lewis, George K

“…Cholera toxin (CT) is a potent adjuvant that activates dendritic cells (DC) by increasing intracellular cyclic AMP (cAMP) levels. In vivo and in vitro, very…”
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Cholera Toxin Indirectly Activates Human Monocyte-Derived Dendritic Cells In Vitro through the Production of Soluble Factors, Including Prostaglandin E sub(2) and Nitric Oxide by Bagley, Kenneth C, Abdelwahab, Sayed F, Tuskan, Robert G, Lewis, George K

“…Cholera toxin (CT) is a potent adjuvant that activates dendritic cells (DC) by increasing intracellular cyclic AMP (cAMP) levels. In vivo and in vitro, very…”
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