Search Results - "Bagley, Alexander"
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Roadmap for metal nanoparticles in radiation therapy: current status, translational challenges, and future directions
Published in Physics in medicine & biology (07-11-2020)“…This roadmap outlines the potential roles of metallic nanoparticles (MNPs) in the field of radiation therapy. MNPs made up of a wide range of materials (from…”
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Deep, noninvasive imaging and surgical guidance of submillimeter tumors using targeted M13-stabilized single-walled carbon nanotubes
Published in Proceedings of the National Academy of Sciences - PNAS (23-09-2014)“…Significance Early detection of cancer positively impacts diagnosis and treatment, ultimately improving patient survival. Using fluorescence imaging offers the…”
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Plasmonic Photothermal Heating of Intraperitoneal Tumors through the Use of an Implanted Near-Infrared Source
Published in ACS nano (24-09-2013)“…Plasmonic nanomaterials including gold nanorods are effective agents for inducing heating in tumors. Because near-infrared (NIR) light has traditionally been…”
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Augmenting the therapeutic window of radiotherapy: A perspective on molecularly targeted therapies and nanomaterials
Published in Radiotherapy and oncology (01-09-2020)“…•Targeted therapies may augment the therapeutic window of radiotherapy, but toxicities from combining radiation and targeted therapy remain a concern in…”
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Radiated, Reconstructed, Recurred
Published in International journal of radiation oncology, biology, physics (01-11-2019)Get full text
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Epilogue: Treatment Plan
Published in International journal of radiation oncology, biology, physics (01-11-2019)Get full text
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Xerostomia-related quality of life for patients with oropharyngeal carcinoma treated with proton therapy
Published in Radiotherapy and oncology (01-01-2020)“…•Proton therapy for oropharyngeal cancer may minimize xerostomia.•Patient-reported xerostomia was worst during treatment but improved at 10 weeks.•At 2 years…”
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Investigation of autosegmentation techniques on T2‐weighted MRI for off‐line dose reconstruction in MR‐linac workflow for head and neck cancers
Published in Medical physics (Lancaster) (01-01-2024)“…Background In order to accurately accumulate delivered dose for head and neck cancer patients treated with the Adapt to Position workflow on the 1.5T magnetic…”
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Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors
Published in Cancer research (Chicago, Ill.) (15-08-2015)“…The delivery of diagnostic and therapeutic agents to solid tumors is limited by physical transport barriers within tumors, and such restrictions directly…”
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Stereotactic ablative radiation therapy for pulmonary metastases: Improving overall survival and identifying subgroups at high risk of local failure
Published in Radiotherapy and oncology (01-04-2020)“…•Retrospective analysis of stereotactic ablative radiation therapy (SABR) for lung metastases.•SABR improved local, intra-thoracic control, and overall…”
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NBTXR3, a first-in-class radioenhancer for pancreatic ductal adenocarcinoma: Report of first patient experience
Published in Clinical and translational radiation oncology (01-03-2022)“…•NBTXR3 is a radioenhancer composed of functionalized hafnium oxide nanoparticles.•This report describes the first patient with pancreatic cancer treated with…”
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Highly conformal reirradiation in patients with prior oropharyngeal radiation: Clinical efficacy and toxicity outcomes
Published in Head & neck (01-11-2020)“…Background Reirradiation of head and neck cancer is associated with high rates of locoregional failure and potentially severe treatment‐related toxicity. We…”
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Radiotherapy reimagined: Integrating nanomedicines into radiotherapy clinical trials
Published in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology (01-05-2023)“…Radioenhancing nanoparticles (NPs) are being evaluated in ongoing clinical trials for various cancers including head and neck, lung, esophagus, pancreas,…”
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Efficacy of proton therapy in children with high‐risk and locally recurrent neuroblastoma
Published in Pediatric blood & cancer (01-08-2019)“…Purpose Proton therapy is currently used in the management of pediatric tumors to decrease late toxicities. However, one of the criticisms of proton therapy is…”
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Effectiveness of the SLICE Program for Youth Concussion Education
Published in Clinical journal of sport medicine (01-09-2012)“…OBJECTIVE:To analyze the effectiveness of the Sports Legacy Institute Community Educators (SLICE) curriculum for student-athletes on recognition and…”
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Hydrogel Spacer Reduces Rectal Dose during Proton Therapy for Prostate Cancer: A Dosimetric Analysis
Published in International journal of particle therapy (2019)“…Proton therapy for prostate cancer may reduce bowel dose and risk of bowel symptoms relative to photon-based methods. Here, we determined the effect of using a…”
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Association of Sociodemographic and Health-Related Factors With Receipt of Nondefinitive Therapy Among Younger Men With High-Risk Prostate Cancer
Published in JAMA network open (02-03-2020)“…Multiple randomized clinical trials have shown that definitive therapy improves overall survival among patients with high-risk prostate cancer. However, many…”
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Advancing cancer immunotherapy through emerging intratumoral delivery and biomedical imaging technologies
Published in Materials today advances (01-12-2024)“…Intratumoral delivery of cytotoxic or immunomodulating compounds is a promising approach for cancer therapy. When a primary tumor or its metastases can be…”
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Hydrogel Spacer Reduces Rectal Dose during Proton Therapy for Prostate Cancer: A Dosimetric Analysis
Published in International journal of particle therapy (01-03-2019)Get full text
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