Search Results - "Baginsky, Walter"
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Enzymatic preparation of high-specific-activity β- d-[6,6′- 3H]fructose-2,6-bisphosphate: Application to a sensitive assay for fructose-2,6-bisphosphatase
Published in Analytical biochemistry (15-11-2010)“…β- d-Fructose-2,6-bisphosphate (Fru-2,6-P 2) is an important regulator of eukaryotic glucose homeostasis, functioning as a potent activator of…”
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Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP−Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor
Published in Journal of the American Chemical Society (13-03-1996)“…Finasteride is employed in treatment of benign prostatic hyperplasia in man, where its target enzyme is steroid 5α-reductase. It is a novel, potent…”
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3
Synthesis of Conformationally Constrained 5,6,7,8-Tetrahydroimidazo[1,5-a]pyridine Inhibitors of Farnesyltransferase
Published in Organic letters (02-11-2000)“…Synthesis of the 8-amino-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine ring system was accomplished by intramolecular cyclization of an iminium ion, derived from…”
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4
Expression and characterization of protein geranylgeranyltransferase type I from the pathogenic yeast Candida albicans and identification of yeast selective enzyme inhibitors
Published in Biochimica et biophysica acta (14-07-2000)“…Protein geranylgeranyltransferase type I (GGTase I) is a heterodimeric zinc metalloenzyme catalyzing protein geranylgeranylation at cysteine residues present…”
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5
In vitro activity of 1,3-beta-D-glucan synthase requires the GTP-binding protein Rho1
Published in The Journal of biological chemistry (14-06-1996)“…In the yeast Saccharomyces cerevisiae, the family of RHO genes are implicated in the control of morphogenetic events although the molecular targets of these…”
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Loss of the Plasma Membrane-Bound Protein Gas1p in Saccharomyces cerevisiae Results in the Release of β1,3-Glucan into the Medium and Induces a Compensation Mechanism To Ensure Cell Wall Integrity
Published in Journal of bacteriology (15-03-1998)“…ABSTRACT Deletion of GAS1/GGP1/CWH52 results in a lower β-glucan content of the cell wall and swollen, more spherical cells (L. Popolo, M. Vai, E. Gatti, S…”
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7
Differential expression and function of two homologous subunits of yeast 1,3-beta-D-glucan synthase
Published in Molecular and Cellular Biology (01-10-1995)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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8
The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-beta-D-glucan synthase
Published in Proceedings of the National Academy of Sciences - PNAS (20-12-1994)“…In Saccharomyces cerevisiae, mutations in FKS1 confer hypersensitivity to the immunosuppressants FK506 and cyclosporin A, while mutations in ETG1 confer…”
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9
In Vitro Activity of 1,3-β-D-Glucan Synthase Requires the GTP-binding Protein Rho1
Published in The Journal of biological chemistry (14-06-1996)“…In the yeast Saccharomyces cerevisiae, the family of RHO genes are implicated in the control of morphogenetic events although the molecular targets of these…”
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10
Activity of 1,3-β-D-Glucan Synthase Requires the GTP-binding Protein Rho1
Published in The Journal of biological chemistry (01-06-1996)Get full text
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11
Identification and Selective Inhibition of an Isozyme of Steroid 5α- Reductase in Human Scalp
Published in Proceedings of the National Academy of Sciences - PNAS (15-11-1992)“…Steroid 5α-reductase (EC 1.3.1.22) catalyzes the reduction of testosterone to dihydrotestosterone. The 5α-reductase found in human scalp has been compared with…”
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12
Loss of the Plasma Membrane-Bound Protein Gas1p inSaccharomyces cerevisiae Results in the Release of β1,3-Glucan into the Medium and Induces a Compensation Mechanism To Ensure Cell Wall Integrity
Published in Journal of Bacteriology (15-03-1998)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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13
Identification and selective inhibition of an isozyme of steroid 5(alpha)-reductase in human scalp
Published in Proceedings of the National Academy of Sciences - PNAS (15-11-1992)“…Steroid 5alpha-reductase catalyzes the reduction of testosterone to dihydrotestosterone. The 5alpha-reductase found in human scalp was compared with enzyme…”
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14
4,7.beta.-Dimethyl-4-azacholestan-3-one (MK-386) and Related 4-Azasteroids as Selective Inhibitors of Human Type 1 5.alpha.-Reductase
Published in Journal of medicinal chemistry (01-11-1994)Get full text
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Evidence for and characterization of a mannitol cycle in Eimeria tenella
Published in Molecular and biochemical parasitology (15-01-1989)“…Recently, it was found that large quantities of mannitol are present in unsporulated oocysts of the protozoan parasite Eimeria tenella and that these levels…”
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