Search Results - "Baghai, T."

SNP and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene provide evidence for association with major depression by ZILL, P, BAGHAI, T. C, ZWANZGER, P, SCHÜLE, C, ESER, D, RUPPRECHT, R, MÖLLER, H.-J, BONDY, B, ACKENHEIL, M

“…Tryptophan hydroxylase (TPH), being the rate-limiting enzyme in the biosynthesis of serotonin plays a major role as candidate gene in several psychiatric…”
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Translocator Protein (18 kDa) as a Target for Novel Anxiolytics with a Favourable Side-Effect Profile by Nothdurfter, C., Rammes, G., Baghai, T. C., Schüle, C., Schumacher, M., Papadopoulos, V., Rupprecht, R.

“…Anxiety disorders are frequent and highly disabling diseases with considerable socio‐economic impact. In the treatment of anxiety disorders, benzodiazepines…”
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Neuroactive steroids in affective disorders: target for novel antidepressant or anxiolytic drugs? by Schüle, C, Eser, D, Baghai, T.C, Nothdurfter, C, Kessler, J.S, Rupprecht, R

“…Abstract In the past decades considerable evidence has emerged that so-called neuroactive steroids do not only act as transcriptional factors in the regulation…”
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Gut microbiota and depression : Pathophysiology of depression: hypothalamic-pituitary-adrenal axis and microbiota-gut-brain axis by Lima-Ojeda, J M, Rupprecht, R, Baghai, T C

“…Depression is a chronic disease with a complex multifactorial and still not fully clarified etiology. Due to new insights after recent investigations of the…”
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Translocator Protein (TSPO) Expression in Platelets of Depressed Patients Decreases during Antidepressant Therapy by Sarubin, N, Baghai, T C, Lima-Ojeda, J M, Melchner, D, Hallof-Buestrich, H, Wolf, L, Hilbert, S, Milenkovic, V M, Wetzel, C H, Rupprecht, R, Nothdurfter, C

“…A promising candidate in the field of pharmacological treatment options regarding major depressive disorder (MDD) is the mitochondrial translocator protein (18…”
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Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolism by BAGHAI, T. C, BINDER, E. B, DEIML, T, UHR, M, ILLIG, T, WICHMANN, H.-E, MODELL, S, NOTHDURFTER, C, HOLSBOER, F, MÜLLER-MYHSOK, B, MÖLLER, H.-J, RUPPRECHT, R, SCHULE, C, BONDY, B, SALYAKINA, D, ESER, D, LUCAE, S, ZWANZGER, P, HABERGER, C, ZILL, P, ISING, M

“…Angiotensin-converting enzyme (ACE) is assumed to influence the activity of the hypothalamic-pituitary-adrenocortical (HPA) system, which shows hyperactivity…”
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Reduced gray matter brain volumes are associated with variants of the serotonin transporter gene in major depression by Frodl, T, Koutsouleris, N, Bottlender, R, Born, C, Jäger, M, Mörgenthaler, M, Scheuerecker, J, Zill, P, Baghai, T, Schüle, C, Rupprecht, R, Bondy, B, Reiser, M, Möller, H-J, Meisenzahl, E M

“…The serotonergic system is involved in the pathophysiology of major depression as well as in the early central nervous system development and adult…”
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Influence of mirtazapine on plasma concentrations of neuroactive steroids in major depression and on 3α-hydroxysteroid dehydrogenase activity by SCHÜLE, C, ROMEO, E, UZUNOV, D. P, ESER, D, DI MICHELE, F, BAGHAI, T. C, PASINI, A, SCHWARZ, M, KEMPTER, H, RUPPRECHT, R

“…Concentrations of 3α-reduced neuroactive steroids are altered in depression and normalize after antidepressant pharmacotherapy with selective serotonin…”
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Gut microbiome and major depressive disorder : The other side of ourselves by Manook, A, Hiergeist, A, Rupprecht, R, Baghai, T C

“…Microbiological ecology and its ambition to describe the complete genome of complex living communities as a whole, have given us powerful tools to characterize…”
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St. John's wort in mild to moderate depression: the relevance of hyperforin for the clinical efficacy by Laakmann, G, Schüle, C, Baghai, T, Kieser, M

“…In a randomized, double-blind, placebo-controlled, multicenter study, the clinical efficacy and safety of two different extracts of St. John's wort were…”
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Neuroactive steroids as modulators of depression and anxiety by Eser, D., Romeo, E., Baghai, T.C., di Michele, F., Schüle, C., Pasini, A., Zwanzger, P., Padberg, F., Rupprecht, R.

“…Certain neuroactive steroids modulate ligand-gated ion channels via non-genomic mechanisms. Especially 3α-reduced pregnane steroids are potent positive…”
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Neuroactive steroids and affective disorders by Eser, D., Schüle, C., Baghai, T.C., Romeo, E., Uzunov, D.P., Rupprecht, R.

“…Neuroactive steroids modulate neurotransmission through modulation of specific neurotransmitter receptors such as γ-aminobutyric acid type A (GABA A)…”
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Brain-derived neurotrophic factor Val66Met polymorphism and dexamethasone/CRH test results in depressed patients by Schüle, Cornelius, Zill, Peter, Baghai, Thomas C., Eser, Daniela, Zwanzger, Peter, Wenig, Nadine, Rupprecht, Rainer, Bondy, Brigitta

“…Data suggest that both neurotrophic and hypothalamic–pituitary–adrenocortical (HPA) systems are involved in the pathophysiology of depression. The aim of the…”
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Effects of Alprazolam on Cholecystokinin-Tetrapeptide-Induced Panic and Hypothalamic-Pituitary-Adrenal-Axis Activity: A Placebo-Controlled Study by ZWANZGER, P, ESER, D, AICHER, S, SCHÜLE, C, BAGHAI, T. C, PADBERG, F, ELLA, R, MÖLLER, H-J, RUPPRECHT, R

“…Cholecystokinin-tetrapeptide (CCK-4) induces panic attacks both in patients with panic disorder (PD) and healthy volunteers. It has been shown that panic…”
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Independent component analysis applied to pharmacological magnetic resonance imaging (phMRI): new insights into the functional networks underlying panic attacks as induced by CCK-4 by Dieler, A C, Sämann, P G, Leicht, G, Eser, D, Kirsch, V, Baghai, T C, Karch, S, Schüle, C, Pogarell, O, Czisch, M, Rupprecht, R, Mulert, C

“…Pharmacological magnetic resonance imaging (phMRI) is a method to study effects of psychopharmacological agents on neural activation. Changes of the blood…”
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Combined action of the ACE D- and the G-protein β3 T-allele in major depression : a possible link to cardiovascular disease? by BONDY, B, BAGHAI, T. C, ZILL, P, BOTTLENDER, R, JAEGER, M, MINOV, C, SCHULE, C, ZWANZGER, P, RUPPRECHT, R, ENGEL, R. R

“…Although it is well established that depression is a major risk factor for the development of coronary artery disease and that cerebrovascular disease can be a…”
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Effects of the GABA-reuptake inhibitor tiagabine on panic and anxiety in patients with panic disorder by Zwanzger, P, Eser, D, Nothdurfter, C, Baghai, T C, Möller, H-J, Padberg, F, Rupprecht, R

“…There is evidence that a decreased GABAergic tone plays a role in the pathophysiology of panic disorder (PD). Selective GABAergic treatment has been suggested…”
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S3 guidelines on diagnostics and therapy of bipolar disorders: development process and essential recommendations by Pfennig, A, Bschor, T, Baghai, T, Bräunig, P, Brieger, P, Falkai, P, Geissler, D, Gielen, R, Giesler, H, Gruber, O, Kopp, I, Meyer, T D, Möhrmann, K H, Muche-Borowski, C, Padberg, F, Scherk, H, Strech, D, Bauer, M

“…Bipolar disorders are severe psychiatric disorders with extensive individual and health economic consequences. Starting in 2007 the first German evidence and…”
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The combined dexamethasone-CRH test before and after repetitive transcranial magnetic stimulation (rTMS) in major depression by Zwanzger, P., Baghai, T.C., Padberg, F., Ella, R., Minov, C., Mikhaiel, P., Schüle, C., Thoma, H., Rupprecht, R.

“…Background: Hypothalamic-pituitary-adrenocortical (HPA) dysregulation assessed by the combined dexamethasone corticotropin releasing hormone test (DEX/CRH…”
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Possible influence of the insertion/deletion polymorphism in the angiotensin I-converting enzyme gene on therapeutic outcome in affective disorders by Baghai, T C, Schüle, C, Zwanzger, P, Minov, C, Schwarz, M J, de Jonge, S, Rupprecht, R, Bondy, B

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