Search Results - "Bagby, J."

Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae by Happel, Kyle I, Dubin, Patricia J, Zheng, Mingquan, Ghilardi, Nico, Lockhart, Christie, Quinton, Lee J, Odden, Anthony R, Shellito, Judd E, Bagby, Gregory J, Nelson, Steve, Kolls, Jay K

“…Interleukin (IL)-23 is a heterodimeric cytokine that shares the identical p40 subunit as IL-12 but exhibits a unique p19 subunit similar to IL-12 p35. IL-12/23…”
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Streptococcus pneumoniae translocates into the myocardium and forms unique microlesions that disrupt cardiac function by Brown, Armand O, Mann, Beth, Gao, Geli, Hankins, Jane S, Humann, Jessica, Giardina, Jonathan, Faverio, Paola, Restrepo, Marcos I, Halade, Ganesh V, Mortensen, Eric M, Lindsey, Merry L, Hanes, Martha, Happel, Kyle I, Nelson, Steve, Bagby, Gregory J, Lorent, Jose A, Cardinal, Pablo, Granados, Rosario, Esteban, Andres, LeSaux, Claude J, Tuomanen, Elaine I, Orihuela, Carlos J

“…Hospitalization of the elderly for invasive pneumococcal disease is frequently accompanied by the occurrence of an adverse cardiac event; these are primarily…”
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Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense by Ye, P, Rodriguez, F H, Kanaly, S, Stocking, K L, Schurr, J, Schwarzenberger, P, Oliver, P, Huang, W, Zhang, P, Zhang, J, Shellito, J E, Bagby, G J, Nelson, S, Charrier, K, Peschon, J J, Kolls, J K

“…Bacterial pneumonia is an increasing complication of HIV infection and inversely correlates with the CD4(+) lymphocyte count. Interleukin (IL)-17 is a cytokine…”
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Biomedical consequences of alcohol use disorders in the HIV-infected host by Molina, Patricia E, Bagby, Gregory J, Nelson, Steve

“…Alcohol abuse is the most common and costly form of drug abuse in the United States. It is well known that alcohol abuse contributes to risky behaviors…”
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DARC on RBC limits lung injury by balancing compartmental distribution of CXC chemokines by Reutershan, Jörg, Harry, Brian, Chang, Daniel, Bagby, Gregory J, Ley, Klaus

“…The Duffy antigen receptor for chemokines (DARC) has a high affinity for CC and CXC chemokines. However, it lacks the ability to induce cell responses that are…”
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Increased granulopoiesis through interleukin-17 and granulocyte colony-stimulating factor in leukocyte adhesion molecule–deficient mice by Forlow, S. Bradley, Schurr, Jill R., Kolls, Jay K., Bagby, Gregory J., Schwarzenberger, Paul O., Ley, Klaus

“…Many mutant mice deficient in leukocyte adhesion molecules display altered hematopoiesis and neutrophilia. This study investigated whether peripheral blood…”
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IL-17 Stimulates Granulopoiesis in Mice: Use of an Alternate, Novel Gene Therapy-Derived Method for In Vivo Evaluation of Cytokines by Schwarzenberger, Paul, La Russa, Vincent, Miller, Allan, Ye, Peng, Huang, Weitao, Zieske, Arthur, Nelson, Steve, Bagby, Gregory J, Stoltz, David, Mynatt, Randall L, Spriggs, Melanie, Kolls, Jay K

“…IL-17 is a novel cytokine secreted principally by CD4+ T cells. It has been shown to support the growth of hemopoietic progenitors in vitro; however, its in…”
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Alcohol impairs the myeloid proliferative response to bacteremia in mice by inhibiting the stem cell antigen-1/ERK pathway by Melvan, John Nicholas, Siggins, Robert W, Stanford, William L, Porretta, Connie, Nelson, Steve, Bagby, Gregory J, Zhang, Ping

“…Enhancement of stem cell Ag-1 (Sca-1) expression by myeloid precursors promotes the granulopoietic response to bacterial infection. However, the underlying…”
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Drug and alcohol use complicate traumatic peripheral vascular injury by Melvan, John Nicholas, Mooney, Jennifer, Bagby, Gregory J, Hunt, John Patrick, Batson, Robert, Greiffenstein, Patrick

“…Drug and alcohol use complicate the presentation and management of traumatic injuries. Impaired hemodynamic recovery and host defense in substance users also…”
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Acute Alcohol Intoxication Impairs the Hematopoietic Precursor Cell Response to Pneumococcal Pneumonia by Raasch, Caroline E., Zhang, Ping, Siggins II, Robert W., LaMotte, Lynn R., Nelson, Steve, Bagby, Gregory J.

“…Background:  Alcohol abuse is associated with an increased incidence and severity of pneumonia. In both the general population and individuals consuming excess…”
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Chronic alcohol abuse and HIV disease progression: studies with the non-human primate model by Amedee, Angela M, Nichols, Whitney A, Robichaux, Spencer, Bagby, Gregory J, Nelson, Steve

“…The populations at risk for HIV infection, as well as those living with HIV, overlap with populations that engage in heavy alcohol consumption. Alcohol use has…”
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Cutting Edge: Roles of Toll-Like Receptor 4 and IL-23 in IL-17 Expression in Response to Klebsiella pneumoniae Infection by Happel, Kyle I, Zheng, Mingquan, Young, Erana, Quinton, Lee J, Lockhart, Euan, Ramsay, Alistair J, Shellito, Judd E, Schurr, Jill R, Bagby, Gregory J, Nelson, Steve, Kolls, Jay K

“…Local production of IL-17 is a significant factor in effective host defense against Gram-negative bacteria. However, the proximal events mediating IL-17…”
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Acute Ethanol Intoxication Suppresses Lung Chemokine Production following Infection with Streptococcus pneumoniae by Boé, Darren M., Nelson, Steve, Zhang, Ping, Bagby, Gregory J.

“…Alcohol intoxication impairs neutrophil function and increases host susceptibility to Streptococcus pneumoniae. In a rat model of pneumonia, the effects of…”
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Innate immunity and pulmonary host defense by Zhang, Ping, Summer, Warren R., Bagby, Gregory J., Nelson, Steve

“…The lung, in order to facilitate gas exchange, represents the largest epithelial surface area of the body in contact with the external environment. As normal…”
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TNF-α Contributes to Endothelial Dysfunction in Ischemia/Reperfusion Injury by Zhang, Cuihua, Xu, Xiangbin, Potter, Barry J, Wang, Wei, Kuo, Lih, Michael, Lloyd, Bagby, Gregory J, Chilian, William M

“…BACKGROUND—Despite the importance of endothelial function for coronary regulation, there is little information and virtually no consensus about the causal…”
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Chronic Binge Alcohol Administration Dysregulates Hippocampal Genes Involved in Immunity and Neurogenesis in Simian Immunodeficiency Virus-Infected Macaques by Maxi, John K, Dean, Matt, Zabaleta, Jovanny, Reiss, Krzysztof, Bagby, Gregory J, Nelson, Steve, Winsauer, Peter J, Peruzzi, Francesca, Molina, Patricia E

“…Alcohol use disorders (AUD) exacerbate neurocognitive dysfunction in Human Immunodeficiency Virus (HIV+) patients. We have shown that chronic binge alcohol…”
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Tumor necrosis factor-α mediates changes in tissue protein turnover in a rat cancer cachexia model by COSTELLI, P, CARBO, N, TESSITORE, L, BAGBY, G. J, LOPEZ-SORIANO, F. J, ARGILES, J. M, BACCINO, F. M

“…Rats bearing the Yoshida AH-130 ascites hepatoma showed enhanced fractional rates of protein degradation in gastrocnemius muscle, heart, and liver, while…”
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Intestinal lymphocyte subsets and turnover are affected by chronic alcohol consumption : Implications for SIV/HIV infection by POONIA, Bhawna, NELSON, Steve, BAGBY, Greg J, VEAZEY, Ronald S

“…We recently demonstrated that simian immunodeficiency virus (SIV) viral loads were significantly higher in the plasma of rhesus macaques consuming alcohol…”
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The systemic and pulmonary LPS binding protein response to intratracheal lipopolysaccharide by Gamble, Lisa, Bagby, Gregory J, Quinton, Lee J, Happel, Kyle I, Mizgerd, Joseph P, Zhang, Ping, Nelson, Steve

“…LPS binding protein (LBP) is an acute-phase glycoprotein that facilitates LPS activation of immune cells through interactions with CD14 and Toll-like receptor…”
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The Granulocyte Colony-Stimulating Factor Response after Intrapulmonary and Systemic Bacterial Challenges by Quinton, Lee J., Nelson, Steve, Boé, Darren M., Zhang, Ping, Zhong, Qiu, Kolls, Jay K., Bagby, Gregory J.

“…In contrast to many cytokines such as tumor necrosis factor (TNF)-α, we hypothesized that, after an intrapulmonary bacterial challenge, lung-derived…”
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