Search Results - "Bagó, Juli"
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Engineered Mesenchymal Stem Cell/Nanomedicine Spheroid as an Active Drug Delivery Platform for Combinational Glioblastoma Therapy
Published in Nano letters (13-03-2019)“…Mesenchymal stem cell (MSC) has been increasingly applied to cancer therapy because of its tumor-tropic capability. However, short retention at target tissue…”
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Electrospun nanofibrous scaffolds increase the efficacy of stem cell-mediated therapy of surgically resected glioblastoma
Published in Biomaterials (01-06-2016)“…Abstract Engineered stem cell (SC)-based therapy holds enormous promise for treating the incurable brain cancer glioblastoma (GBM). Retaining the cytotoxic SCs…”
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Therapeutically engineered induced neural stem cells are tumour-homing and inhibit progression of glioblastoma
Published in Nature communications (02-02-2016)“…Transdifferentiation (TD) is a recent advancement in somatic cell reprogramming. The direct conversion of TD eliminates the pluripotent intermediate state to…”
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Tumor-homing cytotoxic human induced neural stem cells for cancer therapy
Published in Science translational medicine (01-02-2017)“…Engineered neural stem cells (NSCs) are a promising approach to treating glioblastoma (GBM). The ideal NSC drug carrier for clinical use should be easily…”
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Fibrin matrices enhance the transplant and efficacy of cytotoxic stem cell therapy for post-surgical cancer
Published in Biomaterials (01-04-2016)“…Abstract Tumor-homing cytotoxic stem cell (SC) therapy is a promising new approach for treating the incurable brain cancer glioblastoma (GBM). However,…”
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Human umbilical cord blood-derived mesenchymal stem cells promote vascular growth in vivo
Published in PloS one (16-11-2012)“…Stem cell therapies are promising strategies to regenerate human injured tissues, including ischemic myocardium. Here, we examined the acquisition of…”
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Neural stem cell therapy for cancer
Published in Methods (San Diego, Calif.) (15-04-2016)“…•Engineered neural stem cells (NSCs) are a promising new approach to cancer therapy.•NSCs display unique tumor-homing properties that make them ideal drug…”
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A bird's-eye view of cell therapy and tissue engineering for cardiac regeneration
Published in Annals of the New York Academy of Sciences (01-04-2012)“…Complete recovery of ischemic cardiac muscle after myocardial infarction is still an unresolved concern. In recent years, intensive research efforts have…”
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Preclinical scenario of targeting myocardial fibrosis with chimeric antigen receptor (CAR) immunotherapy
Published in Biomedicine & pharmacotherapy (01-02-2023)“…Fibrosis is present in an important proportion of myocardial disorders. Injury activates cardiac fibroblasts, which deposit excess extracellular matrix,…”
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Generation and Profiling of Tumor-Homing Induced Neural Stem Cells from the Skin of Cancer Patients
Published in Molecular therapy (08-07-2020)“…The conversion of human fibroblasts into personalized induced neural stem cells (iNSCs) that actively seek out tumors and deliver cytotoxic agents is a highly…”
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Glioblastoma therapy with cytotoxic mesenchymal stromal cells optimized by bioluminescence imaging of tumor and therapeutic cell response
Published in PloS one (17-04-2012)“…Genetically modified adipose tissue derived mesenchymal stromal cells (hAMSCs) with tumor homing capacity have been proposed for localized therapy of chemo-…”
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NK92 Expressing Anti-BCMA CAR and Secreted TRAIL for the Treatment of Multiple Myeloma: Preliminary In Vitro Assessment
Published in Cells (Basel, Switzerland) (30-11-2023)“…Multiple myeloma (MM) has witnessed improved patient outcomes through advancements in therapeutic approaches. Notably, allogeneic stem cell transplantation,…”
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Bioluminescence imaging of cardiomyogenic and vascular differentiation of cardiac and subcutaneous adipose tissue-derived progenitor cells in fibrin patches in a myocardium infarct model
Published in International journal of cardiology (15-11-2013)“…Abstract Background Adipose tissue-derived progenitor cells (ATDPCs) isolated from human cardiac adipose tissue are useful for cardiac regeneration in rodent…”
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Endothelial Differentiation of Adipose Tissue-Derived Mesenchymal Stromal Cells in Glioma Tumors: Implications for Cell-Based Therapy
Published in Molecular therapy (01-09-2013)“…Multipotent human adipose tissue mesenchymal stromal cells (hAMSCs) are promising therapy vehicles with tumor-homing capacity that can be easily modified to…”
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Calcium phosphate glass improves angiogenesis capacity of poly(lactic acid) scaffolds and stimulates differentiation of adipose tissue-derived mesenchymal stromal cells to the endothelial lineage
Published in Journal of biomedical materials research. Part A (01-04-2013)“…The angiogenic capacity of a new biomaterial composite of poly(lactic acid) and calcium phosphate glass (PLA/CaP) was analyzed by noninvasive bioluminescence…”
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A Bird's-Eye View of Cell Sources for Cell-Based Therapies in Blood Cancers
Published in Cancers (23-05-2020)“…Hematological malignancies comprise over a hundred different types of cancers and account for around 6.5% of all cancers. Despite the significant improvements…”
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Postinfarction Functional Recovery Driven by a Three‐Dimensional Engineered Fibrin Patch Composed of Human Umbilical Cord Blood‐Derived Mesenchymal Stem Cells
Published in Stem cells translational medicine (01-08-2015)“…The ability of a three‐dimensional (3D) engineered fibrin patch with human umbilical cord blood‐derived mesenchymal stem cells (UCBMSCs) to induce recovery of…”
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Image-Guided Resection of Glioblastoma and Intracranial Implantation of Therapeutic Stem Cell-seeded Scaffolds
Published in Journal of visualized experiments (16-07-2018)“…Glioblastoma (GBM), the most common and aggressive primary brain cancer, carries a life expectancy of 12-15 months. The short life expectancy is due in part to…”
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Novel Local "Off-the-Shelf" Immunotherapy for the Treatment of Myeloma Bone Disease
Published in Cells (Basel, Switzerland) (30-01-2023)“…Myeloma bone disease (MBD) is one of the major complications in multiple myeloma (MM)-the second most frequent hematologic malignancy. It is characterized by…”
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Bioluminescence imaging of calvarial bone repair using bone marrow and adipose tissue-derived mesenchymal stem cells
Published in Biomaterials (01-02-2008)“…Abstract A combined strategy using bioluminescence imaging, bone densitometry and histology was used to analyze the bone regeneration capacity of human bone…”
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