Search Results - "Baftizadeh, Fahimeh"
-
1
A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation
Published in Cell (10-06-2021)“…The isocortex and hippocampal formation (HPF) in the mammalian brain play critical roles in perception, cognition, emotion, and learning. We profiled ∼1.3…”
Get full text
Journal Article -
2
Multidimensional View of Amyloid Fibril Nucleation in Atomistic Detail
Published in Journal of the American Chemical Society (29-02-2012)“…Starting from a disordered aggregate, we have simulated the formation of ordered amyloid-like beta structures in a system formed by 18 polyvaline chains in…”
Get full text
Journal Article -
3
The inverted free energy landscape of an intrinsically disordered peptide by simulations and experiments
Published in Scientific reports (26-10-2015)“…The free energy landscape theory has been very successful in rationalizing the folding behaviour of globular proteins, as this representation provides…”
Get full text
Journal Article -
4
Integrated Morphoelectric and Transcriptomic Classification of Cortical GABAergic Cells
Published in Cell (12-11-2020)“…Neurons are frequently classified into distinct types on the basis of structural, physiological, or genetic attributes. To better constrain the definition of…”
Get full text
Journal Article -
5
Nucleation process of a fibril precursor in the C-terminal segment of amyloid-β
Published in Physical review letters (19-04-2013)“…By extended atomistic simulations in explicit solvent and bias-exchange metadynamics, we study the aggregation process of 18 chains of the C-terminal segment…”
Get full text
Journal Article -
6
Joint inference of discrete cell types and continuous type-specific variability in single-cell datasets with MMIDAS
Published in Nature Computational Science (01-09-2024)“…Reproducible definition and identification of cell types is essential to enable investigations into their biological function and to understand their relevance…”
Get full text
Journal Article -
7
-
8
Angle-Directed Nucleation of Paracetamol on Biocompatible Nanoimprinted Polymers
Published in Crystal growth & design (07-06-2017)“…Nucleation kinetics of small-molecule organics can be directed by heterogeneous surfaces imprinted with angular nanopatterns. In this work, we utilized…”
Get full text
Journal Article -
9
Experimental and Mechanistic Study of the Heterogeneous Nucleation and Epitaxy of Acetaminophen with Biocompatible Crystalline Substrates
Published in Crystal growth & design (05-07-2017)“…The presence of different heterogeneous surfaces can directly influence the nucleation kinetics, crystal growth, and morphology of active pharmaceutical…”
Get full text
Journal Article -
10
fMRI single trial discovery of spatio‐temporal brain activity patterns
Published in Human brain mapping (01-03-2017)“…There is growing interest in the description of short‐lived patterns in the spatiotemporal cortical activity monitored via neuroimaging. Most traditional…”
Get full text
Journal Article -
11
Consistent cross-modal identification of cortical neurons with coupled autoencoders
Published in Nature Computational Science (01-02-2021)“…Consistent identification of neurons in different experimental modalities is a key problem in neuroscience. Although methods to perform multimodal measurements…”
Get full text
Journal Article -
12
Thermodynamics of an Intrinsically Disordered Protein by Atomistic Simulations
Published in Biophysical journal (29-01-2013)Get full text
Journal Article -
13
Simulation of Amyloid Nucleation with Bias-Exchange Metadynamics
Published in Biophysical journal (31-01-2012)Get full text
Journal Article