Search Results - "Baeten, L"

Prevalence of peripheral and extra-articular disease in ankylosing spondylitis versus non-radiographic axial spondyloarthritis: a meta-analysis by de Winter, Janneke J, van Mens, Leonieke J, van der Heijde, Désirée, Landewé, Robert, Baeten, Dominique L

“…Peripheral disease (arthritis, enthesitis and dactylitis) and extra-articular disease (uveitis, psoriasis and inflammatory bowel disease) is common in…”
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Emerging role of IL-17 and Th17 cells in systemic lupus erythematosus by Martin, Jérôme C, Baeten, Dominique L, Josien, Régis

“…Abstract Despite the success of targeted therapies in managing immune-mediated inflammatory diseases (IMIDs) such as RA, IBDs, MS and psoriasis, unmet needs…”
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Soil legacies of tree species richness in a young plantation do not modulate tree seedling response to watering regime by Dhiedt, E., Baeten, L., De Smedt, P., Verheyen, K.

“…Trees have a strong and species‐specific influence on biotic and abiotic properties of the soil. Even after the vegetation is removed, the effect can persist…”
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An add-on training program involving breathing exercises, cold exposure, and meditation attenuates inflammation and disease activity in axial spondyloarthritis - A proof of concept trial by Buijze, G A, De Jong, H M Y, Kox, M, van de Sande, M G, Van Schaardenburg, D, Van Vugt, R M, Popa, C D, Pickkers, P, Baeten, D L P

“…The primary objective of this trial was to assess safety and anti-inflammatory effects of an add-on training program involving breathing exercises, cold…”
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Persistently activated, proliferative memory autoreactive B cells promote inflammation in rheumatoid arthritis by Kristyanto, Hendy, Blomberg, Nienke J, Slot, Linda M, van der Voort, Ellen I H, Kerkman, Priscilla F, Bakker, Aleida, Burgers, Leonie E, Ten Brinck, Robin M, van der Helm-van Mil, Annette H M, Spits, Hergen, Baeten, Dominique L, Huizinga, Tom W J, Toes, René E M, Scherer, Hans U

“…Autoreactive B cells mediate autoimmune pathology, but exactly how remains unknown. A hallmark of rheumatoid arthritis (RA), a common autoimmune disease, is…”
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Planet Hunters TESS II: findings from the first two years of TESS by Eisner, N L, Barragán, O, Lintott, C, Aigrain, S, Nicholson, B, Boyajian, T S, Howell, S, Johnston, C, Lakeland, B, Miller, G, McMaster, A, Parviainen, H, Safron, E J, Schwamb, M E, Trouille, L, Vaughan, S, Zicher, N, Allen, C, Allen, S, Bouslog, M, Johnson, C, Simon, M N, Wolfenbarger, Z, Baeten, E M L, Bundy, D M, Hoffman, T

“…ABSTRACT We present the results from the first two years of the Planet Hunters TESS (PHT) citizen science project, which identifies planet candidates in the…”
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Group 2 Innate Lymphoid Cells Attenuate Inflammatory Arthritis and Protect from Bone Destruction in Mice by Omata, Yasunori, Frech, Michael, Primbs, Tatjana, Lucas, Sébastien, Andreev, Darja, Scholtysek, Carina, Sarter, Kerstin, Kindermann, Markus, Yeremenko, Nataliya, Baeten, Dominique L., Andreas, Nico, Kamradt, Thomas, Bozec, Aline, Ramming, Andreas, Krönke, Gerhard, Wirtz, Stefan, Schett, Georg, Zaiss, Mario M.

“…Group 2 innate lymphoid cells (ILC2s) were detected in the peripheral blood and the joints of rheumatoid arthritis (RA) patients, serum-induced arthritis…”
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Inflammatory cytokines epigenetically regulate rheumatoid arthritis fibroblast-like synoviocyte activation by suppressing HDAC5 expression by Angiolilli, Chiara, Grabiec, Aleksander M, Ferguson, Bradley S, Ospelt, Caroline, Malvar Fernandez, Beatriz, van Es, Inge E, van Baarsen, Lisa G M, Gay, Steffen, McKinsey, Timothy A, Tak, Paul P, Baeten, Dominique L, Reedquist, Kris A

“…Epigenetic modifications play an important role in the regulation of gene transcription and cellular function. Here, we examined if pro-inflammatory factors…”
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Systematic validation of specific phenotypic markers for in vitro polarized human macrophages by Ambarus, C.A., Krausz, S., van Eijk, M., Hamann, J., Radstake, T.R.D.J., Reedquist, K.A., Tak, P.P., Baeten, D.L.P.

“…Polarization of macrophages by specific micro-environmental conditions impacts upon their function following subsequent activation. This study aimed to…”
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The Initiation, but Not the Persistence, of Experimental Spondyloarthritis Is Dependent on Interleukin-23 Signaling by van Tok, Melissa N, Na, Songqing, Lao, Christopher R, Alvi, Marina, Pots, Desirée, van de Sande, Marleen G H, Taurog, Joel D, Sedgwick, Jonathon D, Baeten, Dominique L, van Duivenvoorde, Leonie M

“…IL-17A is a central driver of spondyloarthritis (SpA), its production was originally proposed to be IL-23 dependent. Emerging preclinical and clinical evidence…”
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Interleukin 6/Wnt interactions in rheumatoid arthritis: interleukin 6 inhibits Wnt signaling in synovial fibroblasts and osteoblasts by Malysheva, Khrystyna, de Rooij, Karien, Lowik, Clemens Wgm, Baeten, Dominique L, Rose-John, Stefan, Stoika, Rostyslav, Korchynskyi, Olexandr

“…To evaluate the impact of previously unrecognized negative interaction between the Wnt and interleukin (IL) 6 signaling pathways in skeletal tissues as a…”
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Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages by Vogelpoel, Lisa T. C., Hansen, Ivo S., Rispens, Theo, Muller, Femke J. M., van Capel, Toni M. M., Turina, Maureen C., Vos, Joost B., Baeten, Dominique L. P., Kapsenberg, Martien L., de Jong, Esther C., den Dunnen, Jeroen

“…M2 macrophages suppress inflammation in numerous disorders, including tumour formation, infection and obesity. However, the exact role of M2 macrophages in the…”
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Anti-CD74 antibodies have no diagnostic value in early axial spondyloarthritis: data from the spondyloarthritis caught early (SPACE) cohort by de Winter, Janneke J, van de Sande, Marleen G, Baerlecken, Niklas, Berg, Inger, Ramonda, Roberta, van der Heijde, Désirée, van Gaalen, Floris A, Witte, Torsten, Baeten, Dominique L

“…Anti-CD74 IgG antibodies are reported to be elevated in patients with axial spondyloarthritis (axSpA). This study assessed the diagnostic value of anti-CD74…”
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Promotion of macrophage activation by Tie2 in the context of the inflamed synovia of rheumatoid arthritis and psoriatic arthritis patients by Kabala, Pawel A, Malvar-Fernández, Beatriz, Lopes, Ana P, Carvalheiro, Tiago, Hartgring, Sarita A Y, Tang, Man Wai, Conde, Carmen, Baeten, Dominique L, Sleeman, Matthew, Tak, Paul P, Connor, Jane, Radstake, Timothy R, Reedquist, Kris A, García, Samuel

“…Abstract Objective To examine the role of Tie2 signalling in macrophage activation within the context of the inflammatory synovial microenvironment present in…”
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APRIL Induces a Novel Subset of IgA + Regulatory B Cells That Suppress Inflammation via Expression of IL-10 and PD-L1 by Fehres, Cynthia M, van Uden, Nathalie O, Yeremenko, Nataliya G, Fernandez, Leticia, Franco Salinas, Gabriela, van Duivenvoorde, Leonie M, Huard, Bertrand, Morel, Jacques, Spits, Hergen, Hahne, Michael, Baeten, Dominique L P

“…Regulatory B cells (Bregs) are immunosuppressive cells that modulate immune responses through multiple mechanisms. The signals required for the differentiation…”
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Dual Blockade of TNF and IL-17A Inhibits Inflammation and Structural Damage in a Rat Model of Spondyloarthritis by Hammoura, Ihsan, Fiechter, Renee H, Bryant, Shaughn H, Westmoreland, Susan, Kingsbury, Gillian, Waegell, Wendy, Tas, Sander W, Baeten, Dominique L, van de Sande, Marleen G H, van Tok, Melissa N, van Duivenvoorde, Leonie M

“…The tumor necrosis factor (TNF) and IL-23/IL-17 axes are the main therapeutic targets in spondyloarthritis. Despite the clinical efficacy of blocking either…”
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Control of cytokine production by human fc gamma receptors: implications for pathogen defense and autoimmunity by Vogelpoel, Lisa T C, Baeten, Dominique L P, de Jong, Esther C, den Dunnen, Jeroen

“…Control of cytokine production by immune cells is pivotal for counteracting infections via orchestration of local and systemic inflammation. Although their…”
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Expansion of Interleukin‐22– and Granulocyte–Macrophage Colony‐Stimulating Factor–Expressing, but Not Interleukin‐17A–Expressing, Group 3 Innate Lymphoid Cells in the Inflamed Joints of Patients With Spondyloarthritis by Blijdorp, Iris C. J., Menegatti, Silvia, Mens, Leonike J. J., Sande, Marleen G. H., Chen, Sijia, Hreggvidsdottir, Hulda S., Noordenbos, Troy, Latuhihin, Talia E., Bernink, Jochem H., Spits, Hergen, Rogge, Lars, Baeten, Dominique L. P., Yeremenko, Nataliya G.

“…Objective Clinical trials of the anti–interleukin‐17A (anti–IL‐17A) antibody secukinumab have demonstrated a crucial role of the cytokine IL‐17A in the…”
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Do diverse overstoreys induce diverse understoreys? Lessons learnt from an experimental–observational platform in Finland by Ampoorter, E., Baeten, L., Koricheva, J., Vanhellemont, M., Verheyen, K.

“…•Understorey composition showed differences between tree species richness levels.•Tree species richness did not affect understorey alpha diversity.•Highest…”
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Planet Hunters TESS IV: A Massive, Compact Hierarchical Triple Star System TIC 470710327 by Eisner, N. L., Johnston, C., Toonen, S., Frost, A. J., Janssens, S., Lintott, C J, Aigrain, S, Sana, H, Abdul-Masih, M, Arellano-Córdova, K Z, Beck, P G, Bordier, E, Cannon, E, Escorza, A, Fabry, M, Hermansson, L, Howell, S B, Miller, G, Sheyte, S, Alhassan, S, Baeten, E M L, Barnet, F, Bean, S J, Bernau, M, Bundy, D M, Fraia, M Z Di, Emralino, F M, Goodwin, B L, Hermes, P, Hoffman, T, Huten, M, Janíček, R, Lee, S, Mazzucato, M T, Rogers, D J, Rout, M P, Sejpka, J, Tanner, C, Terentev, I A, Urvoy, D

“…We report the discovery and analysis of a massive, compact, hierarchical triple system (TIC 470710327) initially identified by citizen scientists in data…”
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