Search Results - "Baer, Thomas"
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A micromachining-based technology for enhancing germanium light emission via tensile strain
Published in Nature photonics (01-06-2012)“…Germanium is an attractive material for silicon-compatible optoelectronics, but in its bulk form it does not emit light efficiently because of its indirect…”
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Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage
Published in Nature biotechnology (01-10-2010)“…The grading systems used by in vitro fertilization clinics cannot determine reliably whether a given embryo will lead to a successful pregnancy. Wong et al …”
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High-throughput analysis and protein engineering using microcapillary arrays
Published in Nature chemical biology (01-02-2016)“…A new technology platform called μSCALE combines the use of a microcapillary array with laser-based extraction to enable high-throughput biochemical and…”
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A noninvasive BCG skin challenge model for assessing tuberculosis vaccine efficacy
Published in PLoS biology (19-08-2024)“…We report here on the characterisation in mice of a noninvasive bacille Calmette-Guérin (BCG) skin challenge model for assessing tuberculosis (TB) vaccine…”
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Automated Cell Segmentation for Quantitative Phase Microscopy
Published in IEEE transactions on medical imaging (01-04-2018)“…Automated cell segmentation and tracking is essential for dynamic studies of cellular morphology, movement, and interactions as well as other cellular…”
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Novel Chimeric Histone Deacetylase Inhibitors: A Series of Lapatinib Hybrides as Potent Inhibitors of Epidermal Growth Factor Receptor (EGFR), Human Epidermal Growth Factor Receptor 2 (HER2), and Histone Deacetylase Activity
Published in Journal of medicinal chemistry (23-12-2010)“…Reversible lysine-specific acetylation has been described as an important posttranslational modification, regulating chromatin structure and transcriptional…”
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Gene Expression Profiles of Human Breast Cancer Progression
Published in Proceedings of the National Academy of Sciences - PNAS (13-05-2003)“…Although distinct pathological stages of breast cancer have been described, the molecular differences among these stages are largely unknown. Here, through the…”
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Engineering High Affinity Protein–Protein Interactions Using a High-Throughput Microcapillary Array Platform
Published in ACS chemical biology (17-02-2017)“…Affinity maturation of protein–protein interactions requires iterative rounds of protein library generation and high-throughput screening to identify variants…”
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Assessment of ventilation in low-resource healthcare settings: Montserrado County, Liberia—2022−2023
Published in Antimicrobial stewardship & healthcare epidemiology : ASHE (01-06-2023)“…Background: Mitigating the risk of nosocomial respiratory disease transmission in the healthcare facilities of low- and middle−income countries (LMICs) poses…”
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A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen
Published in Cancer cell (01-06-2004)“…Tamoxifen significantly reduces tumor recurrence in certain patients with early-stage estrogen receptor-positive breast cancer, but markers predictive of…”
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No Effect of Musical Training on Frequency Selectivity Estimated Using Three Methods
Published in Trends in hearing (01-04-2019)“…It is widely believed that the frequency selectivity of the auditory system is largely determined by processes occurring in the cochlea. If so, musical…”
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Cell sex affects extracellular matrix protein expression and proliferation of smooth muscle progenitor cells derived from human pluripotent stem cells
Published in Stem cell research & therapy (04-07-2017)“…Smooth muscle progenitor cells (pSMCs) differentiated from human pluripotent stem cells (hPSCs) hold great promise for treating diseases or degenerative…”
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Evaluation of a Frequency-Lowering Algorithm for Adults With High-Frequency Hearing Loss
Published in Trends in hearing (01-10-2017)“…The objective was to determine the effects of a frequency-lowering algorithm (frequency composition, Fcomp) on consonant identification, word-final /s, z/…”
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Changes in Joint Contact Mechanics in a Large Quadrupedal Animal Model After Partial Meniscectomy and a Focal Cartilage Injury
Published in Journal of biomechanical engineering (01-05-2017)“…Acute mechanical damage and the resulting joint contact abnormalities are central to the initiation and progression of post-traumatic osteoarthritis (PTOA)…”
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Proliferative behavior of vaginal fibroblasts from women with pelvic organ prolapse
Published in European journal of obstetrics & gynecology and reproductive biology (01-12-2014)“…Abstract Objective Pelvic organ prolapse (POP) significantly impacts quality of life of women, especially with advancing age. Cell proliferation is a critical…”
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High-speed laser microsurgery of alert fruit flies for fluorescence imaging of neural activity
Published in Proceedings of the National Academy of Sciences - PNAS (12-11-2013)“…Intravital microscopy is a key means of monitoring cellular function in live organisms, but surgical preparation of a live animal for microscopy often is…”
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Exploring the relationship between plasma substance P and glottal incompetence in the elderly
Published in Heliyon (29-02-2024)“…We speculated that increased blood-plasma levels of Substance P may serve as an indicator of glottal incompetence, which is usually indicated by reduced…”
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Dynamic and social behaviors of human pluripotent stem cells
Published in Scientific reports (18-09-2015)“…Human pluripotent stem cells (hPSCs) can self-renew or differentiate to diverse cell types, thus providing a platform for basic and clinical applications…”
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Comparison of Frequency Transposition and Frequency Compression for People With Extensive Dead Regions in the Cochlea
Published in Trends in hearing (01-01-2019)“…The objective was to determine the effects of two frequency-lowering algorithms (frequency transposition, FT, and frequency compression, FC) on audibility,…”
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Brain Activity in Aphonia After a Coughing Episode: Different Brain Activity in Healthy Whispering and Pathological Aphonic Conditions
Published in Journal of voice (01-09-2012)“…Summary A 48-year-old woman visited the authors’ clinic because of aphonia. Laryngeal fiberscopic examination indicated laryngitis and bronchitis, and the…”
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