Search Results - "Baer, Philip G"
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Regional hemodynamic effects of the N-(2-benzoylphenyl)-L-tyrosine peroxisome proliferator-activated receptor-gamma ligand, GI 262570 [(S)-2-(2-benzoylphenylamino)-3-[4-[2-(5-methyl-2-phenyl-2-oxazol-4-yl)ethoxy]phenyl]propionic acid], in conscious rats
Published in The Journal of pharmacology and experimental therapeutics (01-09-2004)“…This study provides novel data on the regional hemodynamic effects of the peroxisome proliferator-activated receptor-gamma activator, GI 262570…”
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Effects of a PPARγ Agonist, GI262570, on Renal Filtration Fraction and Nitric Oxide Level in Conscious Rats
Published in Journal of cardiovascular pharmacology (01-09-2003)“…PPARγ agonists ameliorate insulin resistance and lower blood pressure. Volume expansion/edema has been observed in susceptible patients treated with these…”
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3-[4-(1,2-Diphenylbut-1-enyl)phenyl]acrylic Acid: A Non-Steroidal Estrogen with Functional Selectivity for Bone over Uterus in Rats
Published in Journal of medicinal chemistry (01-05-1994)Get full text
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Biphasic urethral sphincter responses to acetic acid infusion into the lower urinary tract in anesthetized cats
Published in The Journal of urology (01-10-2001)“…Varying the concentration of infused acetic acid produced bladder irritation and dose dependent increases in external urethral sphincter electromyography…”
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Introduction of a conformational switching element on a pyrrolidine ring. Synthesis and evaluation of methyl (R,R)-(.+-.)-3-acetyl-4-[3- (cyclopentyloxy)-4-methoxyphenyl]-3- methyl-1-pyrrolidinecarboxylate, a potent and selective inhibitor of cAMP-specific phosphodiesterase
Published in Journal of medicinal chemistry (01-12-1995)Get full text
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Vasopressor Hyperresponsiveness in New Zealand Genetically Hypertensive Rats
Published in Hypertension (Dallas, Tex. 1979) (01-11-1984)“…The relationship of blood pressure (BP) to vascular hyperresponsiveness to norepinephrine (NE) in New Zealand genetically hypertensive (NZGH) rats was studied…”
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Platelet Activating Factor Vasoconstriction of Dog Kidney Inhibition by Alprazolam
Published in Hypertension (Dallas, Tex. 1979) (01-03-1987)“…Systemic administration of platelet activating factor (PAF; acetyl glyceryl ether phosphorylcholine) reduces renal blood flow, but the mechanism responsible…”
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Comparison of effects of prostaglandins E2 and I2 on rat renal vascular resistance
Published in European journal of pharmacology (15-03-1979)“…Effects of PGE2 and PGI2 on renal vascular resistance (RVR) were compared in anesthetized rats. Renal blood flow and systemic blood pressure were measured…”
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Renal Denervation at Weaning Retards Development of Hypertension in New Zealand Genetically Hypertensive Rats
Published in Hypertension (Dallas, Tex. 1979) (01-05-1982)“…The development of hypertension was studied in 3 to 13-week old New Zealand genetically hypertensive (NZGH) rats subjected to bilateral renal denervation (D)…”
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Effects of gonadectomy and steroid treatment on renal prostaglandin 9-ketoreductase activity in the rat
Published in Life sciences (1973) (05-01-1987)“…The effect of gonadectomy and treatment with sex-steroids on renal prostaglandin 9-ketoreductase activity in 10-11 week old male and female rats was…”
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Renal Prostaglandin Excretion and Metabolism in Male and Female New Zealand Normotensive and Genetically Hypertensive Rats
Published in Hypertension (Dallas, Tex. 1979) (01-03-1981)“…SUMMARY Reduced renal 15-hydroxyprostaglandin dehydrogenase (PGDH) activity has been proposed as a cause, subsequent to elevation of intrarenal prostaglandin…”
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12
Effects of a PPAR?? Agonist, GI262570, on Renal Filtration Fraction and Nitric Oxide Level in Conscious Rats
Published in Journal of cardiovascular pharmacology (01-09-2003)Get full text
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13
Effects of a PPARgamma agonist, GI262570, on renal filtration fraction and nitric oxide level in conscious rats
Published in Journal of cardiovascular pharmacology (01-09-2003)“…PPARgamma agonists ameliorate insulin resistance and lower blood pressure. Volume expansion/edema has been observed in susceptible patients treated with these…”
Get full text
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Bone targeted drugs 2. synthesis of estrogens with hydroxyapatite affinity
Published in Bioorganic & medicinal chemistry letters (07-05-1996)“…The utility of the bone targeting 4-carboxy-3-hydroxy-1,2-pyrazole heterocycle was tested by the synthesis of hybrids with the non-steroidal estrogen…”
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Vasopressin release in male and female rats: effects of gonadectomy and treatment with gonadal steroid hormones
Published in Endocrinology (Philadelphia) (01-09-1985)“…We have found, in normal Wistar rats 10-11 weeks old, that the plasma vasopressin concentration (PADH) and the 24-h urinary excretion of vasopressin (UADHV)…”
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Plasma concentrations, renal excretion, and tissue release of prostaglandins in the rat with dexamethasone-induced hypertension
Published in Endocrinology (Philadelphia) (01-03-1984)“…This study was designed to investigate whether the hypertension produced by dexamethasone in the rat is associated with a deficit in circulating and renal…”
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Augmentation by aprotinin of the renal response to vasopressin
Published in Kidney international (01-05-1987)“…Augmentation by aprotinin of the renal response to vasopressin. We contrasted the renal effects of vasopressin in Brattleboro rats with and without…”
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Renal micropuncture study of normotensive and Milan hypertensive rats before and after development of hypertension
Published in Kidney international (01-06-1978)“…Renal micropuncture study of normotensive and Milan hypertensive rats before and after development of hypertension. Earlier studies of renal transplantation…”
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