Search Results - "Baer, Lisa"

Syndecan-1: A Quantitative Marker for the Endotheliopathy of Trauma by Rodriguez, Erika Gonzalez, MD, Ostrowski, Sisse R., MD, DMSc, Cardenas, Jessica C., PhD, Baer, Lisa A., BSc, Tomasek, Jeffrey S., MD, Henriksen, Hanne H., BSc, Stensballe, Jakob, MD, PhD, Cotton, Bryan A., MD, MPH, FACS, Holcomb, John B., MD, FACS, Johansson, Pär I., MD, DMSc, Wade, Charles E., PhD

“…Abstract Background Endothelial glycocalyx breakdown elicits syndecan-1 shedding, and traumatic endotheliopathy (EoT). We hypothesized that a cutoff syndecan-1…”
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The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue by Lynes, Matthew D, Leiria, Luiz O, Lundh, Morten, Bartelt, Alexander, Shamsi, Farnaz, Huang, Tian Lian, Takahashi, Hirokazu, Hirshman, Michael F, Schlein, Christian, Lee, Alexandra, Baer, Lisa A, May, Francis J, Gao, Fei, Narain, Niven R, Chen, Emily Y, Kiebish, Michael A, Cypess, Aaron M, Blüher, Matthias, Goodyear, Laurie J, Hotamisligil, Gökhan S, Stanford, Kristin I, Tseng, Yu-Hua

“…Cold stimulation induces the synthesis and release of the lipid species 12,13-diHOME from brown adipose tissue. This ‘lipokine’ then acts on brown adipocytes…”
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Maternal Exercise Improves the Metabolic Health of Adult Offspring by Harris, Johan E., Baer, Lisa A., Stanford, Kristin I.

“…The intrauterine environment can modulate the course of development and confer an enduring effect on offspring health. The effects of maternal diet to impair…”
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12,13-diHOME: An Exercise-Induced Lipokine that Increases Skeletal Muscle Fatty Acid Uptake by Stanford, Kristin I., Lynes, Matthew D., Takahashi, Hirokazu, Baer, Lisa A., Arts, Peter J., May, Francis J., Lehnig, Adam C., Middelbeek, Roeland J.W., Richard, Jeffrey J., So, Kawai, Chen, Emily Y., Gao, Fei, Narain, Niven R., Distefano, Giovanna, Shettigar, Vikram K., Hirshman, Michael F., Ziolo, Mark T., Kiebish, Michael A., Tseng, Yu-Hua, Coen, Paul M., Goodyear, Laurie J.

“…Circulating factors released from tissues during exercise have been hypothesized to mediate some of the health benefits of regular physical activity. Lipokines…”
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Traumatic Endotheliopathy: A Prospective Observational Study of 424 Severely Injured Patients by Johansson, Pär I, Henriksen, Hanne H, Stensballe, Jakob, Gybel-Brask, Mikkel, Cardenas, Jessica C, Baer, Lisa A, Cotton, Bryan A, Holcomb, John B, Wade, Charles E, Ostrowski, Sisse R

“…Investigate and confirm the association between sympathoadrenal activation, endotheliopathy and poor outcome in trauma patients. The association between…”
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Paternal Exercise Improves Glucose Metabolism in Adult Offspring by Stanford, Kristin I, Rasmussen, Morten, Baer, Lisa A, Lehnig, Adam C, Rowland, Leslie A, White, Joseph D, So, Kawai, De Sousa-Coelho, Ana Luisa, Hirshman, Michael F, Patti, Mary-Elizabeth, Rando, Oliver J, Goodyear, Laurie J

“…Poor paternal diet has emerged as a risk factor for metabolic disease in offspring, and alterations in sperm may be a major mechanism mediating these…”
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Interferon gamma mediates the reduction of adipose tissue regulatory T cells in human obesity by Bradley, David, Smith, Alan J., Blaszczak, Alecia, Shantaram, Dharti, Bergin, Stephen M., Jalilvand, Anahita, Wright, Valerie, Wyne, Kathleen L., Dewal, Revati S., Baer, Lisa A., Wright, Katherine R., Stanford, Kristin I., Needleman, Bradley, Brethauer, Stacy, Noria, Sabrena, Renton, David, Joseph, Joshua J., Lovett-Racke, Amy, Liu, Joey, Hsueh, Willa A.

“…Decreased adipose tissue regulatory T cells contribute to insulin resistance in obese mice, however, little is known about the mechanisms regulating adipose…”
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A Novel Endocrine Role for the BAT-Released Lipokine 12,13-diHOME to Mediate Cardiac Function by Pinckard, Kelsey M., Shettigar, Vikram K., Wright, Katherine R., Abay, Eaman, Baer, Lisa A., Vidal, Pablo, Dewal, Revati S., Das, Devleena, Duarte-Sanmiguel, Silvia, Hernández-Saavedra, Diego, Arts, Peter J., Lehnig, Adam C., Bussberg, Valerie, Narain, Niven R., Kiebish, Michael A., Yi, Fanchao, Sparks, Lauren M., Goodpaster, Bret H., Smith, Steven R., Pratley, Richard E., Lewandowski, E. Douglas, Raman, Subha V., Wold, Loren E., Gallego-Perez, Daniel, Coen, Paul M., Ziolo, Mark T., Stanford, Kristin I.

“…Brown adipose tissue (BAT) is an important tissue for thermogenesis, making it a potential target to decrease the risks of obesity, type 2 diabetes, and…”
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Sympathoadrenal activation and endotheliopathy are drivers of hypocoagulability and hyperfibrinolysis in trauma: A prospective observational study of 404 severely injured patients by Ostrowski, Sisse R, Henriksen, Hanne H, Stensballe, Jakob, Gybel-Brask, Mikkel, Cardenas, Jessica C, Baer, Lisa A, Cotton, Bryan A, Holcomb, John B, Wade, Charles E, Johansson, Pär I

“…One third of severely injured patients present with a laboratory-based diagnosis of coagulopathy. This study investigated clinical and biomarker profile of…”
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Bone marrow derived mesenchymal stem cells inhibit inflammation and preserve vascular endothelial integrity in the lungs after hemorrhagic shock by Pati, Shibani, Gerber, Michael H, Menge, Tyler D, Wataha, Kathryn A, Zhao, Yuhai, Baumgartner, John Adam, Zhao, Jing, Letourneau, Phillip A, Huby, Maria P, Baer, Lisa A, Salsbury, John R, Kozar, Rosemary A, Wade, Charles E, Walker, Peter A, Dash, Pramod K, Cox, Jr, Charles S, Doursout, Marie-Francoise, Holcomb, John B

“…Hemorrhagic shock (HS) and trauma is currently the leading cause of death in young adults worldwide. Morbidity and mortality after HS and trauma is often the…”
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Elevated Tissue Plasminogen Activator and Reduced Plasminogen Activator Inhibitor Promote Hyperfibrinolysis in Trauma Patients by Cardenas, Jessica C, Matijevic, Nena, Baer, Lisa A, Holcomb, John B, Cotton, Bryan A, Wade, Charles E

“…ABSTRACTSevere hyperfibrinolysis after trauma is a poorly understood phenomenon associated with profound shock, serious anatomic injuries, increased…”
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Measuring thrombin generation as a tool for predicting hemostatic potential and transfusion requirements following trauma by Cardenas, Jessica C, Rahbar, Elaheh, Pommerening, Matthew J, Baer, Lisa A, Matijevic, Nena, Cotton, Bryan A, Holcomb, John B, Wade, Charles E

“…Thrombin is the central coagulation protease that activates clotting proteins, triggers platelet aggregation, and converts fibrinogen to fibrin. Relationships…”
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UCP1‐dependent brown adipose activation accelerates cardiac metabolic remodeling and reduces initial hypertrophic and fibrotic responses to pathological stress by Challa, Azariyas A., Vidal, Pablo, Maurya, Santosh K., Maurya, Chandan K., Baer, Lisa A., Wang, Yang, James, Natasha Maria, Pardeshi, Parth J., Fasano, Matthew, Carley, Andrew N., Stanford, Kristin I., Lewandowski, E. Douglas

“…Brown adipose tissue (BAT) is correlated to cardiovascular health in rodents and humans, but the physiological role of BAT in the initial cardiac remodeling at…”
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Differential Responses to Sigma-1 or Sigma-2 Receptor Ablation in Adiposity, Fat Oxidation, and Sexual Dimorphism by Li, Jing, Félix-Soriano, Elisa, Wright, Katherine R, Shen, Hongtao, Baer, Lisa A, Stanford, Kristin I, Guo, Lian-Wang

“…Obesity is increasing at epidemic rates across the US and worldwide, as are its co-morbidities, including type-2 diabetes and cardiovascular disease. Thus,…”
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Lipidomic Adaptations in White and Brown Adipose Tissue in Response to Exercise Demonstrate Molecular Species-Specific Remodeling by May, Francis J., Baer, Lisa A., Lehnig, Adam C., So, Kawai, Chen, Emily Y., Gao, Fei, Narain, Niven R., Gushchina, Liubov, Rose, Aubrey, Doseff, Andrea I., Kiebish, Michael A., Goodyear, Laurie J., Stanford, Kristin I.

“…Exercise improves whole-body metabolic health through adaptations to various tissues, including adipose tissue, but the effects of exercise training on the…”
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βIV-Spectrin regulates STAT3 targeting to tune cardiac response to pressure overload by Unudurthi, Sathya D, Nassal, Drew, Greer-Short, Amara, Patel, Nehal, Howard, Taylor, Xu, Xianyao, Onal, Birce, Satroplus, Tony, Hong, Deborah, Lane, Cemantha, Dalic, Alyssa, Koenig, Sara N, Lehnig, Adam C, Baer, Lisa A, Musa, Hassan, Stanford, Kristin I, Smith, Sakima, Mohler, Peter J, Hund, Thomas J

“…Heart failure (HF) remains a major source of morbidity and mortality in the US. The multifunctional Ca2+/calmodulin-dependent kinase II (CaMKII) has emerged as…”
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Maternal Exercise and Paternal Exercise Induce Distinct Metabolite Signatures in Offspring Tissues by Hernández-Saavedra, Diego, Markunas, Christina, Takahashi, Hirokazu, Baer, Lisa A, Harris, Johan E, Hirshman, Michael F, Ilkayeva, Olga, Newgard, Christopher B, Stanford, Kristin I, Goodyear, Laurie J

“…That maternal and paternal exercise improve the metabolic health of adult offspring is well established. Tissue and serum metabolites play a fundamental role…”
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Hepatic protein kinase Cbeta deficiency mitigates late-onset obesity by Shu, Yaoling, Gumma, Nikhil, Hassan, Faizule, Branch, Daniel A., Baer, Lisa A., Ostrowski, Michael C., Stanford, Kristin I., Baskin, Kedryn K., Mehta, Kamal D.

“…Although aging is associated with progressive adiposity and a decline in liver function, the underlying molecular mechanisms and metabolic interplay are…”
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Exercise Training Induces Depot-Specific Adaptations to White and Brown Adipose Tissue by Lehnig, Adam C., Dewal, Revati S., Baer, Lisa A., Kitching, Kathryn M., Munoz, Vitor Rosetto, Arts, Peter J., Sindeldecker, Devin A., May, Francis J., Lauritzen, Hans P.M.M., Goodyear, Laurie J., Stanford, Kristin I.

“…Exercise affects whole-body metabolism through adaptations to various tissues, including adipose tissue (AT). Recent studies investigated exercise-induced…”
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Out of the Ivory Tower, into the Digital World? Democratising Scholarly Exchange by Raeburn, Fraser, Baer‐Tsarfati, Lisa, Porter, Viktoria

“…The year 2020 has witnessed an unprecedented expansion of scholarly events online. Yet, in the scramble to adapt to difficult circumstances, little reflection…”
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