Search Results - "Baek, Ahreum"
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Elucidation of Gene Expression Patterns in the Brain after Spinal Cord Injury
Published in Cell transplantation (01-07-2017)“…Spinal cord injury (SCI) is a devastating neurological disease. The pathophysiological mechanisms of SCI have been reported to be relevant to central nervous…”
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2
Therapeutic effects of polydeoxyribonucleotide in an in vitro neuronal model of ischemia/reperfusion injury
Published in Scientific reports (12-04-2023)“…Polydeoxyribonucleotide (PDRN) is an agonist that selectively stimulates adenosine A 2A receptor (ADORA2A), which suppresses inflammatory responses…”
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3
Polydeoxyribonucleotide ameliorates IL-1β-induced impairment of chondrogenic differentiation in human bone marrow-derived mesenchymal stem cells
Published in Scientific reports (30-10-2024)“…Osteoarthritis (OA) is a degenerative disease of the joints, prevalent worldwide. Polydeoxyribonucleotide (PDRN) is used for treating knee OA. However, the…”
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4
Effect of Polydeoxyribonucleotide on Angiogenesis and Wound Healing in an In Vitro Model of Osteoarthritis
Published in Cell transplantation (01-11-2018)“…Osteoarthritis (OA) is degenerative disease, leading to pain and functional disability. It is reported that polydeoxyribonucleotide (PDRN) is a suitable…”
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5
Exposure to an enriched environment modulates the synaptic vesicle cycle in a mouse spinal cord injury model
Published in Scientific reports (25-05-2024)“…Spinal cord injury (SCI) leads to motor and sensory impairment below the site of injury, thereby necessitating rehabilitation. An enriched environment (EE)…”
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3'-Sialyllactose Protects SW1353 Chondrocytic Cells From Interleukin-1β-Induced Oxidative Stress and Inflammation
Published in Frontiers in pharmacology (12-04-2021)“…Osteoarthritis (OA) is a major degenerative joint disease. Oxidative stress and inflammation play key roles in the pathogenesis of OA. 3'-Sialyllactose (3'-SL)…”
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Environmental Enrichment Enhances Cav 2.1 Channel-Mediated Presynaptic Plasticity in Hypoxic–Ischemic Encephalopathy
Published in International journal of molecular sciences (26-03-2021)“…Hypoxic–ischemic encephalopathy (HIE) is a devastating neonatal brain condition caused by lack of oxygen and limited blood flow. Environmental enrichment (EE)…”
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Very early environmental enrichment protects against apoptosis and improves functional recovery from hypoxic-ischemic brain injury
Published in Frontiers in molecular neuroscience (07-02-2023)“…Appropriate rehabilitation of stroke patients at a very early phase results in favorable outcomes. However, the optimal strategy for very early rehabilitation…”
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The Differential Effects of Repetitive Magnetic Stimulation in an In Vitro Neuronal Model of Ischemia/Reperfusion Injury
Published in Frontiers in neurology (13-02-2018)“…Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive therapy that has been implicated in treatment of serious neurological disorders. However,…”
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High-Frequency Repetitive Magnetic Stimulation Enhances the Expression of Brain-Derived Neurotrophic Factor Through Activation of Ca2+–Calmodulin-Dependent Protein Kinase II–cAMP-Response Element-Binding Protein Pathway
Published in Frontiers in neurology (07-05-2018)“…Repetitive transcranial magnetic stimulation (rTMS) can be used in various neurological disorders. However, neurobiological mechanism of rTMS is not well…”
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11
3′-Sialyllactose alleviates bone loss by regulating bone homeostasis
Published in Communications biology (19-01-2024)“…Osteoporosis is a common skeletal disease that results in an increased risk of fractures. However, there is no definitive cure, warranting the development of…”
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The Modulation of Neurotrophin and Epigenetic Regulators: Implication for Astrocyte Proliferation and Neuronal Cell Apoptosis After Spinal Cord Injury
Published in Annals of rehabilitation medicine (01-08-2016)“…To investigate alterations in the expression of the main regulators of neuronal survival and death related to astrocytes and neuronal cells in the brain in a…”
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13
Environmental Enrichment Upregulates Striatal Synaptic Vesicle-Associated Proteins and Improves Motor Function
Published in Frontiers in neurology (16-07-2018)“…Environmental enrichment (EE) is a therapeutic paradigm that consists of complex combinations of physical, cognitive, and social stimuli. The mechanisms…”
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14
Correction to “Macrocyclic Immunoproteasome Inhibitors as a Potential Therapy for Alzheimer’s Disease”
Published in Journal of medicinal chemistry (28-03-2024)Get full text
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15
In vivo gene editing via homology-independent targeted integration for adrenoleukodystrophy treatment
Published in Molecular therapy (05-01-2022)“…Adrenoleukodystrophy (ALD) is caused by various pathogenic mutations in the X-linked ABCD1 gene, which lead to metabolically abnormal accumulations of very…”
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Randomized, triple-blind, placebo-controlled study to evaluate the safety of 6′-Sialyllactose in healthy adults
Published in Regulatory toxicology and pharmacology (01-03-2022)“…Sialyllactoses (SL) are an abundant component of human milk. There have been many studies on the biological effects of SL in humans. SL can be produced using…”
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Macrocyclic Immunoproteasome Inhibitors as a Potential Therapy for Alzheimer’s Disease
Published in Journal of medicinal chemistry (12-08-2021)“…Previously, we reported that immunoproteasome (iP)-targeting linear peptide epoxyketones improve cognitive function in mouse models of Alzheimer’s disease (AD)…”
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18
Low-frequency repetitive magnetic stimulation suppresses neuroblastoma progression by downregulating the Wnt/β-catenin signaling pathway
Published in Bioelectrochemistry (Amsterdam, Netherlands) (01-10-2022)“…[Display omitted] •• Low-frequency repetitive magnetic stimulation (rMS) suppressed neuroblastoma.•• Low-frequency rMS downregulated Wnt/β-catenin signalling…”
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19
Effect of Polydeoxyribonucleotide on Angiogenesis and Wound Healing in an Model of Osteoarthritis
Published in Cell transplantation (01-11-2018)“…Osteoarthritis (OA) is degenerative disease, leading to pain and functional disability. It is reported that polydeoxyribonucleotide (PDRN) is a suitable…”
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Journal Article -
20
Parasympathetic Effect Induces Cell Cycle Activation in Upper Limbs of Paraplegic Patients with Spinal Cord Injury
Published in International journal of molecular sciences (27-11-2019)“…The present study aimed to investigate gene expression changes related to cell cycle activation in patients with spinal cord injury (SCI) and to further…”
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