Search Results - "Baehr, A."

Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy by Moretti, A., Fonteyne, L., Giesert, F., Hoppmann, P., Meier, A. B., Bozoglu, T., Baehr, A., Schneider, C. M., Sinnecker, D., Klett, K., Fröhlich, T., Rahman, F. Abdel, Haufe, T., Sun, S., Jurisch, V., Kessler, B., Hinkel, R., Dirschinger, R., Martens, E., Jilek, C., Graf, A., Krebs, S., Santamaria, G., Kurome, M., Zakhartchenko, V., Campbell, B., Voelse, K., Wolf, A., Ziegler, T., Reichert, S., Lee, S., Flenkenthaler, F., Dorn, T., Jeremias, I., Blum, H., Dendorfer, A., Schnieke, A., Krause, S., Walter, M. C., Klymiuk, N., Laugwitz, K. L., Wolf, E., Wurst, W., Kupatt, C.

“…Frameshift mutations in the DMD gene, encoding dystrophin, cause Duchenne muscular dystrophy (DMD), leading to terminal muscle and heart failure in patients…”
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Staying active after rehab: Physical activity perspectives with a spinal cord injury beyond functional gains by Baehr, Laura A, Kaimal, Girija, Hiremath, Shivayogi V, Trost, Zina, Finley, Margaret

“…Lifestyle physical activity following spinal cord injury (SCI) is critical for functional independence, mental wellness, and social participation, yet nearly…”
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LEA29Y expression in transgenic neonatal porcine islet-like cluster promotes long-lasting xenograft survival in humanized mice without immunosuppressive therapy by Buerck, L. Wolf-van, Schuster, M., Oduncu, F. S., Baehr, A., Mayr, T., Guethoff, S., Abicht, J., Reichart, B., Klymiuk, N., Wolf, E., Seissler, J.

“…Genetically engineered pigs are a promising source for islet cell transplantation in type 1 diabetes, but the strong human anti-pig immune response prevents…”
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Re-irradiation for recurrent glioblastoma multiforme: a critical comparison of different concepts by Baehr, A., Trog, D., Oertel, M., Welsch, S., Kröger, K., Grauer, O., Haverkamp, U., Eich, H. T.

“…Purpose Purpose of this study was to investigate outcome and toxicity of re-irradiation for recurrent primary glioblastoma (rGBM). We evaluated a group of…”
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A preclinical Talbot–Lau prototype for x‐ray dark‐field imaging of human‐sized objects by Hauke, C., Bartl, P., Leghissa, M., Ritschl, L., Sutter, S. M., Weber, T., Zeidler, J., Freudenberger, J., Mertelmeier, T., Radicke, M., Michel, T., Anton, G., Meinel, F. G., Baehr, A., Auweter, S., Bondesson, D., Gaass, T., Dinkel, J., Reiser, M., Hellbach, K.

“…Purpose Talbot–Lau x‐ray interferometry provides information about the scattering and refractive properties of an object — in addition to the object's…”
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Worth a local treatment? - Analysis of modern radiotherapy concepts for oligometastatic prostate cancer by Oertel, M, Scobioala, S, Kroeger, K, Baehr, A, Stegger, L, Haverkamp, U, Schäfers, M, Eich, H-T

“…Prostate cancer (PCA) is the most-prevalent non-skin cancer in men worldwide. Nevertheless, the treatment of oligometastatic, especially lymph-node (ln)…”
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mHealth-Based Just-in-Time Adaptive Intervention to Improve the Physical Activity Levels of Individuals With Spinal Cord Injury: Protocol for a Randomized Controlled Trial by Carey, Rachel L, Le, Ha, Coffman, Donna L, Nahum-Shani, Inbal, Thirumalai, Mohanraj, Hagen, Cole, Baehr, Laura A, Schmidt-Read, Mary, Lamboy, Marlyn S R, Kolakowsky-Hayner, Stephanie A, Marino, Ralph J, Intille, Stephen S, Hiremath, Shivayogi V

“…The lack of regular physical activity (PA) in individuals with spinal cord injury (SCI) in the United States is an ongoing health crisis. Regular PA and…”
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WS03.2 MKA 104, a long-acting ENaC down-regulator, enhances speed of ciliary transport of secretions on wild-type and CFTR(–/–) pig trachea with greater efficacy and duration than existing CF treatments by Hall, R, Cole, P, Baehr, A, Klymiuk, N

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192 Variability in Survival From Emergency Care Sensitive Conditions Across Emergency Care Service Regions in Pennsylvania by Karp, D.N, Baehr, A, Delgado, M.K, Kilaru, A.S, Wiebe, D.J, Carr, B.G

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Pharmacology and pharmacokinetics of fentanyl toxicity reversal by anti‐fentanyl monoclonal antibodies in combination with naloxone by Baehr, Carly A., Pravetoni, Marco

“…AIM Widespread access to illicit fentanyl has contributed to an ongoing epidemic of fatal drug overdoses in the United States. The incidence of fatal overdoses…”
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Monoclonal Antibodies Engineered with Fc Region Mutations to Extend Protection against Fentanyl Toxicity by Khaimraj, Aaron, Baehr, Carly A, Hicks, Dustin, Raleigh, Michael D, Pravetoni, Marco

“…Fentanyl and other synthetic opioids are the leading cause of drug-related deaths in the United States. mAbs that selectively target fentanyl and fentanyl…”
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Pharmacological Profiling of Antifentanyl Monoclonal Antibodies in Combination with Naloxone in Pre- and Postexposure Models of Fentanyl Toxicity by Baehr, Carly A, Wu, Mariah M, Pandit, Sujata G, Arias-Umana, Jose, AuCoin, David, Pravetoni, Marco

“…The incidence of fatal drug overdoses in the United States is an alarming public health threat that has been exacerbated by the COVID-19 pandemic, resulting in…”
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Quantitative Sensory Changes Related to Physical Activity in Adult Populations: A Scoping Review by Baehr, Laura A., Frey-Law, Laura A., Finley, Margaret

“…Exercise-induced hypoalgesia related to physical activity produces sensory adaptations, but its mechanism remains unclear. Quantitative sensory testing is an…”
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Calibration measurements on the DEPFET Detectors for the MIXS instrument on BepiColombo by Majewski, P., Aschauer, F., Aschauer, S., Bähr, A., Bergbauer, B., Hilchenbach, M., Krumrey, M., Laubis, C., Lauf, T., Lechner, P., Lutz, G., Scholze, F., Soltau, H., Stefanescu, A., Strüder, L., Treis, J.

“…The Mercury Imaging X-ray Spectrometer (MIXS) will be launched on board of the 5th ESA cornerstone mission BepiColombo. The two channel instrument MIXS is…”
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Effect of Tele-exercise to Promote Empowered Movement for Individuals With Spinal Cord Injury (TEEMS) Program on Physical Activity Determinants and Behavior: A Mixed Methods Assessment by Baehr, Laura A, Hiremath, Shivayogi V, Bruneau, Jr, Michael, Chiarello, Lisa A, Kaimal, Girija, Newton, Ross, Finley, Margaret

“…To assess the effects of group tele-exercise participation on physical activity (PA) determinants and behavior as identified by social cognitive theory (SCT)…”
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Development and Feasibility of a Group Tele-Exercise Program for Individuals With Spinal Cord Injury by Baehr, Laura A., Kaimal, Girija, Bruneau, Michael, Finley, Margaret

“…More than 50% of individuals with spinal cord injury (SCI) report no regular exercise due to numerous barriers to participation. Tele-exercise services offer…”
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Baseline Comparison of Exercisers and Nonexercisers With Spinal Cord Injury Enrolled in a Group Tele-Exercise Program by Baehr, Laura A, Bruneau, Jr, Michael, Finley, Margaret

“…Individuals with SCI are 1.5 times more likely to be sedentary compared to adults without disabilities or chronic health conditions. It is therefore imperative…”
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Contribution of Antibody-Mediated Effector Functions to the Mechanism of Efficacy of Vaccines for Opioid Use Disorders by Huseby Kelcher, April M., Baehr, Carly A., Hamid, Fatima A., Hart, Geoffrey T., Pravetoni, Marco

“…Abstract Vaccines and mAbs offer promising strategies to treat substance use disorders (SUDs) and prevent overdose. Despite vaccines and mAbs against SUDs…”
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Fostering Responsible Conduct of Research for Early-Stage Investigators: Challenges and Opportunities by Sinko, Laura, Baehr, Laura A, Murray, Elizabeth Heller, Kobulsky, Julia, Mcloughlin, Gabriella M, Schroeder, Krista, Schumacher, Leah M

“…The rise of academic misconduct poses significant challenges to the integrity and credibility of scholarly research. Early-stage investigators (ESIs),…”
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Genomically Incorporated 5-Fluorouracil that Escapes UNG-Initiated Base Excision Repair Blocks DNA Replication and Activates Homologous Recombination by Huehls, Amelia M, Huntoon, Catherine J, Joshi, Poorval M, Baehr, Carly A, Wagner, Jill M, Wang, Xiaoxiao, Lee, Marietta Y, Karnitz, Larry M

“…5-Fluorouracil (5-FU) and its metabolite 5-fluorodeoxyuridine (FdUrd, floxuridine) are chemotherapy agents that are converted to 5-fluorodeoxyuridine…”
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