Search Results - "Bae, Bongmin"
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Emerging Roles for 3' UTRs in Neurons
Published in International journal of molecular sciences (12-05-2020)“…The 3' untranslated regions (3' UTRs) of mRNAs serve as hubs for post-transcriptional control as the targets of microRNAs (miRNAs) and RNA-binding proteins…”
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Coordination of alternative splicing and alternative polyadenylation revealed by targeted long read sequencing
Published in Nature communications (07-09-2023)“…Nervous system development is associated with extensive regulation of alternative splicing (AS) and alternative polyadenylation (APA). AS and APA have been…”
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CRISPR-Mediated Knockout of Long 3' UTR mRNA Isoforms in mESC-Derived Neurons
Published in Frontiers in genetics (17-12-2021)“…Alternative cleavage and polyadenylation (APA) is pervasive, occurring for more than 70% of human and mouse genes. Distal poly(A) site selection to generate…”
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Allelic chromatin structure precedes imprinted expression of Kcnk9 during neurogenesis
Published in Genes & development (01-09-2023)“…Differences in chromatin state inherited from the parental gametes influence the regulation of maternal and paternal alleles in offspring. This phenomenon,…”
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Elimination of Calm1 long 3'-UTR mRNA isoform by CRISPR-Cas9 gene editing impairs dorsal root ganglion development and hippocampal neuron activation in mice
Published in RNA (Cambridge) (01-10-2020)“…The majority of mouse and human genes are subject to alternative cleavage and polyadenylation (APA), which most often leads to the expression of two or more…”
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