Search Results - "Badria, Farid"

Formulation of Nanospanlastics as a Promising Approach for ‎Improving the Topical Delivery of a Natural Leukotriene Inhibitor (3-‎Acetyl-11-Keto-β-Boswellic Acid): Statistical Optimization, in vitro ‎Characterization, and ex vivo Permeation Study by Badria, Farid, Mazyed, Eman

“…The current study aimed to discuss the potential of nanospanlastics as a surfactant-based vesicular system for improving the topical delivery of…”
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Curcumin Attenuates Iron Accumulation and Oxidative Stress in the Liver and Spleen of Chronic Iron-Overloaded Rats by Badria, Farid A, Ibrahim, Ahmed S, Badria, Adel F, Elmarakby, Ahmed A

“…Iron overload is now recognized as a health problem in industrialized countries, as excessive iron is highly toxic for liver and spleen. The potential use of…”
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Synthesis and antitumor evaluation of some new 1,3,4-oxadiazole-based heterocycles by Bondock, Samir, Adel, Shymaa, Etman, Hassan A., Badria, Farid A.

“…The synthetic strategies and characterization of some novel 1,3,4-oxadiazole derivatives carrying different pharmacophores and heterocyclic rings that are…”
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Synthesis of new thiazolo-pyrrolidine–(spirooxindole) tethered to 3-acylindole as anticancer agents by Islam, Mohammad Shahidul, Ghawas, Hussien Mansur, El-Senduny, Fardous F., Al-Majid, Abdullah Mohammed, Elshaier, Yaseen A.M.M., Badria, Farid A., Barakat, Assem

“…[Display omitted] •Spirooxindole derivatives 4a–n were synthesized and tested against anti-cancer activities.•Compounds 4b–d, 4f, 4j, and 4k showed potent…”
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Development of Provesicular Nanodelivery System of Curcumin as a Safe and Effective Antiviral Agent: Statistical Optimization, In Vitro Characterization, and Antiviral Effectiveness by Badria, Farid A, Abdelaziz, Abdelaziz E, Hassan, Amira H, Elgazar, Abdullah A, Mazyed, Eman A

“…Curcumin is a natural compound that has many medical applications. However, its low solubility and poor stability could impede its clinical applications. The…”
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Natural inspired piperine-based ureas and amides as novel antitumor agents towards breast cancer by Elimam, Diaaeldin M, Elgazar, Abdullah A, El-Senduny, Fardous F, El-Domany, Ramadan A, Badria, Farid A, Eldehna, Wagdy M

“…In this work, the natural piperine moiety was utilised to develop two sets of piperine-based amides ( ) and ureas ( ) as potential anticancer agents. The…”
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Correction: Curcumin attenuates iron accumulation and oxidative stress in the liver and spleen of chronic iron-overloaded rats by Badria, Farid A, Ibrahim, Ahmed S, Badria, Adel F, Elmarakby, Ahmed A

“…[This corrects the article DOI: 10.1371/journal.pone.0134156.]…”
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Identification of sulphonamide-tethered N-((triazol-4-yl)methyl)isatin derivatives as inhibitors of SARS-CoV-2 main protease by ElNaggar, Mai H., Elgazar, Abdullah A., Gamal, Ghada, Hamed, Shimaa M., Elsayed, Zainab M., El-Ashrey, Mohamed K., Abood, Amira, El Hassab, Mahmoud A., Soliman, Ahmed M., El-Domany, Ramadan A., Badria, Farid A., Supuran, Claudiu T., Eldehna, Wagdy M.

“…SARS-CoV-2 pandemic in the end of 2019 led to profound consequences on global health and economy. Till producing successful vaccination strategies, the…”
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Theophylline-based hybrids as acetylcholinesterase inhibitors endowed with anti-inflammatory activity: synthesis, bioevaluation, in silico and preliminary kinetic studies by Elgazar, Abdullah A, El-Domany, Ramadan A, Eldehna, Wagdy M, Badria, Farid A

“…In this study, we investigated the conjugation of theophylline with different compounds of natural origin hoping to construct new hybrids with dual activity…”
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Formulation of Sodium Valproate Nanospanlastics as a Promising Approach for Drug Repurposing in the Treatment of Androgenic Alopecia by Badria, Farid. A., Fayed, Hassan A., Ibraheem, Amira K., State, Ahmed F., Mazyed, Eman A.

“…Sodium valproate (SV) is an antiepileptic drug that is widely used in the treatment of different seizure disorders. The topical SV has a hair regenerative…”
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Utilization of selected natural products as complementary therapeutic approach for Obstructive Sleep Apnea (OSA) management: a literature review by Badria, Farid A., Elgazar, Abdullah A.

“…Background Obstructive sleep apnea (OSA) is one of the foremost potential severe disorders, with frequent episodes of complete or partial obstructions of the…”
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Bioassay-Guided Isolation, Metabolic Profiling, and Docking Studies of Hyaluronidase Inhibitors from Ravenala madagascariensis by Mohamed, Esraa M, Hetta, Mona H, Rateb, Mostafa E, Selim, Mohamed A, AboulMagd, Asmaa M, Badria, Farid A, Abdelmohsen, Usama Ramadan, Alhadrami, Hani A, Hassan, Hossam M

“…Hyaluronidase enzyme (HAase) has a role in the dissolution or disintegration of hyaluronic acid (HA) and in maintaining the heathy state of skin…”
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Microbial Transformation of the Sesquiterpene Lactone, Vulgarin, by Aspergillus niger by ElGamal, Reem A, Galala, Amal A, Abdel-Kader, Maged S, Badria, Farid A, Soliman, Amal F

“…The biotransformation of vulgarin , an eudesmanolides-type sesquiterpene lactone obtained from , by the microorganism, , was carried out to give three more…”
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Natural inspired piperine-based sulfonamides and carboxylic acids as carbonic anhydrase inhibitors: Design, synthesis and biological evaluation by Elimam, Diaaeldin M., Elgazar, Abdullah A., Bonardi, Alessandro, Abdelfadil, Mohamed, Nocentini, Alessio, El-Domany, Ramadan A., Abdel-Aziz, Hatem A., Badria, Farid A., Supuran, Claudiu T., Eldehna, Wagdy M.

“…The natural product piperine, the major bioactive alkaloid present in black pepper fruits, has the ability to modulate the functional activity of several…”
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Metabolic Profiling, GC‐MS, LC‐ESI‐MS/MS Analysis, Phenolics Isolation and Biological Evaluation of the Aerial Parts Extracts of Felicia abyssinica L by Elshorbagy, Ahmed M., Fayed, Marwa A. A., Sallam, Amal, Badria, Farid A.

“…Felicia abyssinica L., family Asteraceae, is widely used in folk medicine. This represents the first study to investigate its phytoconstituents and…”
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Effect of phenolic compounds from the leaves of Psidium guajava on the activity of three metabolism‐related enzymes by Ahmed, Mohamed H., Aldesouki, Hala M., Badria, Farid A.

“…Enzyme activity modulation by synthetic compounds provide strategies combining the inhibitory and therapeutic mode of action of the confirmed inhibitors…”
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Synthesis and Antiviral Activity of New Indole-Based Heterocycles by Abdel-Gawad, Hassan, Mohamed, Hanan Ahmed, Dawood, Kamal Mohamed, Badria, Farid Abdel-Rahem

“…New 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazine and 1,3-thiazole derivatives incorporating indole nucleus were prepared using 3-acetylindole as precursor and…”
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Substituted spirooxindole derivatives as potent anticancer agents through inhibition of phosphodiesterase 1 by Barakat, Assem, Islam, Mohammad Shahidul, Ghawas, Hussien Mansur, Al-Majid, Abdullah Mohammed, El-Senduny, Fardous F, Badria, Farid A, Elshaier, Yaseen A. M. M, Ghabbour, Hazem A

“…Spirooxindole is a promising chemo therapeutic agent. Possible targets include cancers of the liver, prostate, lung, stomach, colon, and breast. Here, we…”
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Synthesis of Pyridine-Dicarboxamide-Cyclohexanone Derivatives: Anticancer and α-Glucosidase Inhibitory Activities and In Silico Study by Al-Majid, Abdullah Mohammed, Islam, Mohammad Shahidul, Atef, Saleh, El-Senduny, Fardous F, Badria, Farid A, Elshaier, Yaseen A M M, Ali, M, Barakat, Assem, Motiur Rahman, A F M

“…An efficient and practical method for the synthesis of 2,6-diaryl-4-oxo- , '-di(pyridin-2-yl)cyclohexane-1,1-dicarboxamide is described in this present study,…”
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Design and synthesis of new substituted spirooxindoles as potential inhibitors of the MDM2–p53 interaction by Barakat, Assem, Islam, Mohammad Shahidul, Ghawas, Hussien Mansur, Al-Majid, Abdullah Mohammed, El-Senduny, Fardous F., Badria, Farid A., Elshaier, Yaseen A.M.M., Ghabbour, Hazem A.

“…[Display omitted] •The manuscript involved design of substituted spirooxindoles as MDM2-p53 inhibitors.•The design was corroborated via molecular docking of…”
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