Search Results - "Badr, Mona"
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Novel Polyfunctional Pyridines as Anticancer and Antioxidant Agents. Synthesis, Biological Evaluation and in Silico ADME-T Study
Published in Chemical & pharmaceutical bulletin (2017)“…Two series of novel alkoxylated 2-oxo(imino)-3-pyridinecarbonitriles (structurally-relevant to some reported anticancer pyridines with phosphodiesterase 3A…”
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2
Design and synthesis of some thiazolyl and thiadiazolyl derivatives of antipyrine as potential non-acidic anti-inflammatory, analgesic and antimicrobial agents
Published in Bioorganic & medicinal chemistry (15-01-2009)“…The synthesis of two groups of structure hybrids comprising basically the antipyrine moiety attached to either polysubstituted thiazole or…”
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3
Bifunctional ethyl 2-amino-4-methylthiazole-5-carboxylate derivatives: Synthesis and in vitro biological evaluation as antimicrobial and anticancer agents
Published in European journal of medicinal chemistry (09-04-2014)“…Thirty thiazole compounds bearing chemotherapeutically-active pharmacophores were synthesized and evaluated for their preliminary in vitro antimicrobial and…”
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4
Benzodioxole–Pyrazole Hybrids as Anti‐Inflammatory and Analgesic Agents with COX‐1,2/5‐LOX Inhibition and Antioxidant Potential
Published in Archiv der Pharmazie (Weinheim) (01-05-2017)“…Two series of benzodioxole–pyrazole hybrids were synthesized and the IC50 values for in vitro inhibition of the enzymes cyclooxygenase 1/2 (COX‐1, COX‐2) and…”
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5
1,4-Disubstituted-5-hydroxy-3-methylpyrazoles and some derived ring systems as cytotoxic and DNA binding agents. Synthesis, in vitro biological evaluation and in silico ADME study
Published in Medicinal chemistry research (01-02-2018)“…Some novel polysubstituted pyrazoles, bipyrazoles and pyranopyrazoles, supported with various chemotherapeutically-active pharmacophores, were synthesized and…”
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6
Structure-based development of novel triazoles and related thiazolotriazoles as anticancer agents and Cdc25A/B phosphatase inhibitors. Synthesis, in vitro biological evaluation, molecular docking and in silico ADME-T studies
Published in European journal of medicinal chemistry (20-10-2017)“…Synthesis of twenty nine new 1,2,4-triazoles and some derived thiazolothiadiazoles (structurally-relevant to some reported triazoles with anticancer and/or…”
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Advancing IBDV diagnostics: a one-step multiplex real-time qRT-PCR for discriminating between vvIBDV and non-vvIBDV viruses, including the newly emerged IBDV variant
Published in Frontiers in veterinary science (18-07-2024)“…The very virulent infectious bursal disease virus (vvIBDV) induces an acute, highly contagious and immunosuppressive disease in younger chicken causing massive…”
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8
Isolation and Genotypic Characterization of New Emerging Avian Reovirus Genetic Variants in Egypt
Published in Poultry (31-03-2023)“…Avian reovirus (ARV) strains cause a variety of symptoms in chickens, including viral arthritis/tenosynovitis, a disease that has emerged as a significant…”
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Synthesis of some novel benzoxazole derivatives as anticancer, anti-HIV-1 and antimicrobial agents
Published in European journal of medicinal chemistry (01-09-2005)“…In an effort to establish new candidates with improved antineoplastic, anti-HIV-1 and antimicrobial activities we report here the synthesis and in vitro…”
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Synthesis and anticancer activity of novel benzimidazole and benzothiazole derivatives against HepG2 liver cancer cells
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01-03-2012)“…Most of cancer chemotherapeutics and chemopreventives exert their effects by triggering apoptotic cell death. In this study, novel benzimidazole and…”
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11
Synthesis of Some 1,4,6-Trisubstituted-2-oxo-1,2-dihydropyridine-3-carbonitriles and Their Biological Evaluation as Cytotoxic and Antimicrobial Agents
Published in Archiv der Pharmazie (Weinheim) (01-11-2015)“…A series of novel 1,4,6‐trisubstituted‐2‐oxo‐1,2‐dihydropyridine‐3‐carbonitriles supported with some functionalities reported to contribute to significant…”
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12
Synthesis of Some Pyrazolines and Pyrimidines Derived from Polymethoxy Chalcones as Anticancer and Antimicrobial Agents
Published in Archiv der Pharmazie (Weinheim) (01-09-2011)“…The synthesis of a series of certain polymethoxy chalcones and some derived pyrazole, pyrimidine, and thiazolopyrimidine ring structures is reported. Eleven…”
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13
Intra-articular injection of platelet-rich plasma and therapeutic exercise in knee osteoarthritis
Published in Egyptian Rheumatology and Rehabilitation (2019)“…Context There is no definite treatment strategy capable of decreasing destruction of cartilage and enhancing its healing. Intra-articular injection of…”
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Design, synthesis and molecular docking study of some substituted 4,5- dihydro-2H-indazole derivatives as potential anti-inflammatory agents
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01-08-2013)“…A new series of 4,5-dihydro-2H-indazoles was synthesized and evaluated for anti-inflammatory activity using formalin-induced paw edema and turpentine…”
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15
Dual inhibitors of hepatitis C virus and hepatocellular carcinoma: design, synthesis and docking studies
Published in Future science OA (01-01-2018)“…Simultaneous inhibition of hepatitis C virus (HCV) and hepatocellular carcinoma (HCC) may enhance anti-HCV effects and reduce resistance and side effects…”
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16
Perfused nonfunctioning renal allograft : case report and review of the literature
Published in Saudi journal of kidney diseases and transplantation (2018)“…We report a case of very early postoperative iatrogenic dissection of common iliac artery (CIA), external iliac artery (EIA) causing acute ischemia of the…”
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17
Novel Polyfunctional Pyridines as Anticancer and Antioxidant Agents. Synthesis, Biological Evaluation and in Silico ADME-T Study
Published in Chemical and Pharmaceutical Bulletin (01-05-2017)“…Two series of novel alkoxylated 2-oxo(imino)-3-pyridinecarbonitriles (structurally-relevant to some reported anticancer pyridines with phosphodiesterase 3A…”
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18
Synthesis of Some Novel Substituted Purine Derivatives As Potential Anticancer, Anti-HIV-1 and Antimicrobial Agents
Published in Archiv der Pharmazie (Weinheim) (01-04-2007)“…In search of novel purine antimetabolites, a series of 8‐substituted methylxanthine derivatives was prepared in order to explore their in vitro anticancer,…”
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19
Brain abscess due to streptococcus intermedius in a young patient secondary to partially treated sinusitis
Published in Journal of nature and science of medicine (01-01-2019)Get full text
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20
Diagnostic Value of Exhaled Carbon Monoxide as an Early Marker of Exacerbation in Children with Chronic Lung Diseases
Published in ISRN pediatrics (2012)“…Chronic airways infection and inflammation are leading causes of morbidity and mortality in chronic lung diseases (CLD). Pulmonary exacerbations are major…”
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