Search Results - "Badiavas, Evangelos V."

Role of Mesenchymal Stem Cells in Dermal Repair in Burns and Diabetic Wounds by Maranda, Eric L, Rodriguez-Menocal, Luis, Badiavas, Evangelos V

“…In this review we explore stem cell function in wounds that are resistant to healing, such as burn injuries and diabetic wounds. Diabetic ulcers are of…”
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Extracellular Vesicles as Therapeutic Tools for the Treatment of Chronic Wounds by Bray, Eric R., Oropallo, Alisha R., Grande, Daniel A., Kirsner, Robert S., Badiavas, Evangelos V.

“…Chronic wounds develop when the orderly process of cutaneous wound healing is delayed or disrupted. Development of a chronic wound is associated with…”
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Proteomic analysis of bone marrow-derived mesenchymal stem cell extracellular vesicles from healthy donors: implications for proliferation, angiogenesis, Wnt signaling, and the basement membrane by McBride, Jeffrey D, Rodriguez-Menocal, Luis, Guzman, Wellington, Khan, Aisha, Myer, Ciara, Liu, Xiaochen, Bhattacharya, Sanjoy K, Badiavas, Evangelos V

“…Background Bone marrow-derived mesenchymal stem cells (BM-MSCs) have shown therapeutic potential in various in vitro and in vivo studies in cutaneous wound…”
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Participation of bone marrow derived cells in cutaneous wound healing by Badiavas, Evangelos V., Abedi, Mehrdad, Butmarc, Janet, Falanga, Vincent, Quesenberry, Peter

“…Bone marrow has long been known to be a source of stem cells capable of regeneration of the hematopoeitic system. Recent reports, however, have indicated that…”
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Assessment of Ablative Fractional CO2 Laser and Er:YAG Laser to Treat Hypertrophic Scars in a Red Duroc Pig Model by Rodriguez-Menocal, Luis, Davis, Stephen S, Becerra, Sandra, Salgado, Marcela, Gill, Joel, Valdes, Jose, Candanedo, Ambar, Natesan, Shanmugasundaram, Solis, Michael, Guzman, Wellington, Higa, Alex, Schulman, Carl I, Christy, Robert J, Waibel, Jill, Badiavas, Evangelos V

“…Hypertrophic scarring is a fibroproliferative process that occurs following a third-degree dermal burn injury, producing significant morbidity due to…”
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Atypical Fibroxanthoma Treated with a Topical Combination of Imiquimod, Tazarotene, and 5-Fluorouracil by Nahm, William J., Badiavas, Evangelos V., Kirsner, Robert S., Boyd, Carter J., Arthur, Anita A., Bae, Sean, Shen, John

“…This case report describes an 80-year-old man who presented with a growing erythematous nodule with erosion, measuring 0.6 cm × 0.6 cm, on his right temple…”
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Percutaneous bone marrow transplantation using fractional ablative Erbium:YAG laser by Rodriguez-Menocal, Luis, Salgado, Marcela, Davis, Stephen, Waibel, Jill, Shabbir, Arsalan, Cox, Audrey, Badiavas, Evangelos V

“…Topical application of therapeutic agents has been a mainstay in Dermatology for the treatment of skin disorders but is not commonly used for systemic…”
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Agonistic analogs of growth hormone releasing hormone (GHRH) promote wound healing by stimulating the proliferation and survival of human dermal fibroblasts through ERK and AKT pathways by Cui, Tengjiao, Jimenez, Joaquin J, Block, Norman L, Badiavas, Evangelos V, Rodriguez-Menocal, Luis, Vila Granda, Ailin, Cai, Renzhi, Sha, Wei, Zarandi, Marta, Perez, Roberto, Schally, Andrew V

“…Decreased or impaired proliferation capability of dermal fibroblasts interferes with successful wound healing. Several growth factors tested failed to fully…”
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Transgenic expression of a canonical Wnt inhibitor, kallistatin, is associated with decreased circulating CD19+ B lymphocytes in the peripheral blood by McBride, Jeffrey D., Liu, Xiaochen, Berry, William L., Janknecht, Ralf, Cheng, Rui, Zhou, Kelu, Badiavas, Evangelos V., Ma, Jian-xing

“…Members of the family of serine proteinase inhibitors, such as kallistatin, have been shown to inhibit canonical Wnt-TCF/LEF-β-catenin signaling via their…”
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Extracellular Vesicles as Biomarkers and Therapeutics in Dermatology: A Focus on Exosomes by McBride, Jeffrey D., Rodriguez-Menocal, Luis, Badiavas, Evangelos V.

“…Extracellular vesicles (exosomes, microvesicles, and apoptotic bodies) are ubiquitous in human tissues, circulation, and body fluids. Of these vesicles,…”
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Treating keratinocyte carcinomas with a combination of imiquimod, 5-fluorouracil, and tretinoin using store-and-forward telemedicine in the age of coronavirus disease 2019 to promote social distancing by Nahm, William J., Badiavas, Evangelos V., Kirsner, Robert S., Nichols, Anna J., Harris, Zechariah C., Phillips, Andrew R., Shen, John

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Bone Marrow Mesenchymal Stem Cell-Derived CD63 + Exosomes Transport Wnt3a Exteriorly and Enhance Dermal Fibroblast Proliferation, Migration, and Angiogenesis In Vitro by McBride, Jeffrey D, Rodriguez-Menocal, Luis, Guzman, Wellington, Candanedo, Ambar, Garcia-Contreras, Marta, Badiavas, Evangelos V

“…Wnts are secreted glycoproteins that regulate stem cell self-renewal, differentiation, and cell-to-cell communication during embryonic development and in adult…”
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Long-term bone marrow culture and its clinical potential in chronic wound healing by Badiavas, Evangelos V., Ford, Dwayne, Liu, Paul, Kouttab, Nicola, Morgan, John, Richards, Amy, Maizel, Abby

“…ABSTRACT Bone marrow‐derived cells have long been regarded to play a crucial role in the homeostasis of skin. We have previously described the clinical benefit…”
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Mesenchymal Stem Cell-Derived Extracellular Vesicles as an Advanced Therapy for Chronic Wounds by Bray, Eric R, Kirsner, Robert S, Badiavas, Evangelos V

“…Chronic wounds are a significant challenge for patients, healthcare providers, and healthcare systems. Chronic wounds develop due to a complex interplay…”
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Erythematous Papules After Microneedle Therapy for Facial Rejuvenation by Cervantes, Jessica, Hafeez, Farhaan, Badiavas, Evangelos V

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Research Techniques Made Simple: Molecular Docking in Dermatology - A Foray into In Silico Drug Discovery by Issa, Naiem T., Badiavas, Evangelos V., Schürer, Stephan

“…Drug discovery is a complex process with many potential pitfalls. To go to market, a drug must undergo extensive preclinical optimization followed by clinical…”
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Dual mechanism of type VII collagen transfer by bone marrow mesenchymal stem cell extracellular vesicles to recessive dystrophic epidermolysis bullosa fibroblasts by McBride, Jeffrey D., Rodriguez-Menocal, Luis, Candanedo, Ambar, Guzman, Wellington, Garcia-Contreras, Marta, Badiavas, Evangelos V.

“…Recessive dystrophic epidermolysis bullosa (RDEB) is a severe blistering disease resulting from a lack of type VII collagen production. Recent clinical trials…”
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Association of Human Papillomavirus Vaccine With the Development of Keratinocyte Carcinomas by Nichols, Anna J, Allen, Amber Heyna, Shareef, Shahjahan, Badiavas, Evangelos V, Kirsner, Robert S, Ioannides, Tim

“…Keratinocyte carcinomas (KCs), consisting of squamous cell carcinomas (SCCs) and basal cell carcinomas (BCCs), are the most common human malignant neoplasms…”
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Characterization of novel therapies for epidermolysis bullosa in clinical development: a cross-sectional analysis by Sandoval, Aaron Gabriel W., Kempinski, Heidi, Hartman, Shelley, Badiavas, Evangelos V.

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Significance of N-methyl-d-aspartate (NMDA) receptor-mediated signaling in human keratinocytes by Nahm, Walter K., Philpot, Benjamin D., Adams, Michelle M., Badiavas, Evangelos V., Zhou, Linda H., Butmarc, Janet, Bear, Mark F., Falanga, Vincent

“…Increasing data suggest that glutamate might act as a cell‐signaling molecule in non‐neuronal tissues such as the skin. Here we demonstrate the presence of…”
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