Search Results - "Badertscher, Remo P"

Examining Uncertainty in In Vitro–In Vivo Extrapolation Applied in Fish Bioconcentration Models by Laue, Heike, Hostettler, Lu, Badertscher, Remo P, Jenner, Karen J, Sanders, Gordon, Arnot, Jon A, Natsch, Andreas

“…In vitro biotransformation rates were determined for 30 chemicals, mostly fragrance ingredients, using trout liver S9 fractions (RT-S9) and incorporated into…”
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p-Alkyl-Benzoyl-CoA Conjugates as Relevant Metabolites of Aromatic Aldehydes With Rat Testicular Toxicity-Studies Leading to the Design of a Safer New Fragrance Chemical by Laue, Heike, Kern, Susanne, Badertscher, Remo P, Ellis, Graham, Natsch, Andreas

“…Several aromatic aldehydes such as 3-(4-tert-butylphenyl)-2-methylpropanal were shown to adversely affect the reproductive system in male rats following oral…”
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Benzoyl-CoA conjugate accumulation as an initiating event for male reprotoxic effects in the rat? Structure–activity analysis, species specificity, and in vivo relevance by Laue, Heike, Badertscher, Remo P., Hostettler, Lu, Weiner-Sekiya, Yumiko, Haupt, Tina, Nordone, Adrian, Adamson, Gregory M., Natsch, Andreas

“…A number of para -substituted benzoic acids ( p -BA) and chemicals metabolized to p -BA have been found to confer adverse effects in male rats on sperm…”
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Oxidative Tryptophan Modification by Terpene- and Squalene-Hydroperoxides and a Possible Link to Cross-Reactions in Diagnostic Tests by Natsch, Andreas, Emter, Roger, Badertscher, Remo P, Brunner, Gerhard, Granier, Thierry, Kern, Susanne, Ellis, Graham

“…Hydroperoxides can act as specific haptens and oxidatively modify proteins. Terpene hydroperoxides trigger unusually high frequencies of positive skin…”
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Grafting of α-tocopherol upon γ-irradiation in UHMWPE probed by model hydrocarbons by Badertscher, Remo P., Lerf, Reto, Delfosse, Daniel, Adlhart, Christian

“…Today, UHMWPE implants are stabilized with α-tocopherol and cross-linked by irradiation in order to reduce wear. Little is known about the structural…”
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