Search Results - "Bader, Stefanie M."

Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection by Doerflinger, Marcel, Deng, Yexuan, Whitney, Paul, Salvamoser, Ranja, Engel, Sven, Kueh, Andrew J., Tai, Lin, Bachem, Annabell, Gressier, Elise, Geoghegan, Niall D., Wilcox, Stephen, Rogers, Kelly L., Garnham, Alexandra L., Dengler, Michael A., Bader, Stefanie M., Ebert, Gregor, Pearson, Jaclyn S., De Nardo, Dominic, Wang, Nancy, Yang, Chenying, Pereira, Milton, Bryant, Clare E., Strugnell, Richard A., Vince, James E., Pellegrini, Marc, Strasser, Andreas, Bedoui, Sammy, Herold, Marco J.

“…Programmed cell death contributes to host defense against pathogens. To investigate the relative importance of pyroptosis, necroptosis, and apoptosis during…”
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Macrophage and neutrophil death programs differentially confer resistance to tuberculosis by Stutz, Michael Dominic, Allison, Cody Charles, Ojaimi, Samar, Preston, Simon Peter, Doerflinger, Marcel, Arandjelovic, Philip, Whitehead, Lachlan, Bader, Stefanie M., Batey, Daniel, Asselin-Labat, Marie-Liesse, Herold, Marco J., Strasser, Andreas, West, Nicholas P., Pellegrini, Marc

“…Apoptosis can potently defend against intracellular pathogens by directly killing microbes and eliminating their replicative niche. However, the reported…”
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Environmental sensing and regulation of motility in Toxoplasma by Uboldi, Alessandro D., Wilde, Mary‐Louise, Bader, Stefanie M., Tonkin, Christopher J.

“…Toxoplasma and other apicomplexan parasites undergo a unique form of cellular locomotion referred to as “gliding motility.” Gliding motility is crucial for…”
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Necroptosis does not drive disease pathogenesis in a mouse infective model of SARS-CoV-2 in vivo by M. Bader, Stefanie, Cooney, James P., Bhandari, Reet, Mackiewicz, Liana, Dayton, Merle, Sheerin, Dylan, Georgy, Smitha Rose, Murphy, James M., Davidson, Kathryn C., Allison, Cody C., Pellegrini, Marc, Doerflinger, Marcel

“…Necroptosis, a type of lytic cell death executed by the pseudokinase Mixed Lineage Kinase Domain-Like (MLKL) has been implicated in the detrimental…”
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Conservation, abundance, glycosylation profile, and localization of the TSP protein family in Cryptosporidium parvum by John, Alan, M. Bader, Stefanie, Madiedo Soler, Niccolay, Wiradiputri, Kharizta, Tichkule, Swapnil, Smyth, Sean T., Ralph, Stuart A., Jex, Aaron R., Scott, Nichollas E., Tonkin, Christopher J., Goddard-Borger, Ethan D.

“…Cryptosporidium parvum is a zoonotic apicomplexan parasite and a common cause of diarrheal disease worldwide. The development of vaccines to prevent or limit…”
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Transcriptional modification of host cells harboring Toxoplasma gondii bradyzoites prevents IFN gamma-mediated cell death by Seizova, Simona, Ruparel, Ushma, Garnham, Alexandra L., Bader, Stefanie M., Uboldi, Alessandro D., Coffey, Michael J., Whitehead, Lachlan W., Rogers, Kelly L., Tonkin, Christopher J.

“…Toxoplasma gondii develops a latent infection in the muscle and central nervous system that acts as a reservoir for acute-stage reactivation in vulnerable…”
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A necroptosis-independent function of RIPK3 promotes immune dysfunction and prevents control of chronic LCMV infection by Preston, Simon P., Allison, Cody C., Schaefer, Jan, Clow, William, Bader, Stefanie M., Collard, Sophie, Forsyth, Wasan O., Clark, Michelle P., Garnham, Alexandra L., Li-Wai-Suen, Connie S. N., Peiris, Thanushi, Teale, Jack, Mackiewicz, Liana, Davidson, Sophia, Doerflinger, Marcel, Pellegrini, Marc

“…Necroptosis is a lytic and inflammatory form of cell death that is highly constrained to mitigate detrimental collateral tissue damage and impaired immunity…”
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Programmed cell death: the pathways to severe COVID-19? by Bader, Stefanie M, Cooney, James P, Pellegrini, Marc, Doerflinger, Marcel

“…Two years after the emergence of SARS-CoV-2, our understanding of COVID-19 disease pathogenesis is still incomplete. Despite unprecedented global collaborative…”
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Epigenetic Silencing of RIPK3 in Hepatocytes Prevents MLKL-mediated Necroptosis From Contributing to Liver Pathologies by Preston, Simon P., Stutz, Michael D., Allison, Cody C., Nachbur, Ueli, Gouil, Quentin, Tran, Bang Manh, Duvivier, Valerie, Arandjelovic, Philip, Cooney, James P., Mackiewicz, Liana, Meng, Yanxiang, Schaefer, Jan, Bader, Stefanie M., Peng, Hongke, Valaydon, Zina, Rajasekaran, Pravin, Jennison, Charlie, Lopaticki, Sash, Farrell, Ann, Ryan, Marno, Howell, Jess, Croagh, Catherine, Karunakaran, Denuja, Schuster-Klein, Carole, Murphy, James M., Fifis, Theodora, Christophi, Christopher, Vincan, Elizabeth, Blewitt, Marnie E., Thompson, Alexander, Boddey, Justin A., Doerflinger, Marcel, Pellegrini, Marc

“…Necroptosis is a highly inflammatory mode of cell death that has been implicated in causing hepatic injury including steatohepatitis/ nonalcoholic…”
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SARS-CoV-2 mouse adaptation selects virulence mutations that cause TNF-driven age-dependent severe disease with human correlates by Bader, Stefanie M, Cooney, James P, Sheerin, Dylan, Taiaroa, George, Harty, Leigh, Davidson, Kathryn C, Mackiewicz, Liana, Dayton, Merle, Wilcox, Stephen, Whitehead, Lachlan, Rogers, Kelly L, Georgy, Smitha Rose, Coussens, Anna K, Grimley, Samantha L, Corbin, Vincent, Pitt, Miranda, Coin, Lachlan, Pickering, Raelene, Thomas, Merlin, Allison, Cody C, McAuley, Julie, Purcell, Damian F J, Doerflinger, Marcel, Pellegrini, Marc

“…The diversity of COVID-19 disease in otherwise healthy people, from seemingly asymptomatic infection to severe life-threatening disease, is not clearly…”
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Endothelial Caspase-8 prevents fatal necroptotic hemorrhage caused by commensal bacteria by Bader, Stefanie M., Preston, Simon P., Saliba, Katie, Lipszyc, Adam, Grant, Zoe L., Mackiewicz, Liana, Baldi, Andrew, Hempel, Anne, Clark, Michelle P., Peiris, Thanushi, Clow, William, Bjelic, Jan, Stutz, Michael D., Arandjelovic, Philip, Teale, Jack, Du, Fashuo, Coultas, Leigh, Murphy, James M., Allison, Cody C., Pellegrini, Marc, Samson, Andre L.

“…Caspase-8 transduces signals from death receptor ligands, such as tumor necrosis factor, to drive potent responses including inflammation, cell proliferation…”
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