Search Results - "Badenhorst, Danelle"

Impact and mechanisms of action of neurotensin on cardiac contractility in the rat left ventricle by Osadchii, Oleg, Norton, Gavin, Deftereos, Dawn, Badenhorst, Danelle, Woodiwiss, Angela

“…Using immunoassay measurements, neurotensin was identified in rat ventricular tissue and in coronary effluent samples. Exogenous neurotensin evoked contractile…”
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The relationship between the nitric oxide synthase gene and the risk of hypertension defi ned according to ambulatory blood pressures by Candy, Geoffrey, Badenhorst, Danelle, Libhaber, Elena, Sareli, Pinhas, Norton, Gavin R., Brooksbank, Richard, Woodiwiss, Angela J.

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The relationship between the nitric oxide synthase gene and the risk of hypertension defined according to ambulatory blood pressures by Geoffrey Candy, Danelle Badenhorst, Elena Libhaber, Pinhas Sareli, Gavin R. Norton, Richard Brooksbank, Angela J. Woodiwiss

“…Although nitric oxide (NO) plays an important role in blood pressure (BP) control, whether variation of genes involved in regulating the synthesis of NO…”
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Cross-linking influences the impact of quantitative changes in myocardial collagen on cardiac stiffness and remodelling in hypertension in rats by BADENHORST, Danelle, MASEKO, Muzi, TSOTETSI, Oupa J, NAIDOO, Alvin, BROOKSBANK, Richard, NORTON, Gavin R, WOODIWISS, Angela J

“…To assess whether the variable impact of quantitative changes in myocardial collagen on left ventricular (LV) diastolic myocardial stiffness (myocardial k) and…”
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Therapy of ischemic cardiomyopathy with the immunomodulating agent pentoxifylline: Results of a randomized study by SLIWA, Karen, WOODIWISS, Angela, KONE, Veuvette N, CANDY, Geoffrey, BADENHORST, Danelle, NORTON, Gavin, ZAMBAKIDES, Chris, PETERS, Ferande, ESSOP, Rafique

“…Inflammatory immune activation commonly occurs in heart failure and may perpetuate this syndrome. We sought to determine whether the immunomodulating agent…”
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Effects of pentoxifylline on cytokine profiles and left ventricular performance in patients with decompensated congestive heart failure secondary to idiopathic dilated cardiomyopathy by Sliwa, Karen, Woodiwiss, Angela, Candy, Geoffrey, Badenhorst, Danelle, Libhaber, Carlos, Norton, Gavin, Skudicky, Daniel, Sareli, Pinhas

“…Patients with severe heart failure have plasma cytokine concentrations that are more than twofold greater than those in patients with moderate heart failure…”
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Impact of Aldosterone Receptor Blockade on the Deleterious Cardiac Effects of Adrenergic Activation in Hypertensive Rats by Veliotes, Demetri G A, Norton, Gavin R, Correia, Raul J, Strijdom, Hans, Badenhorst, Danelle, Brooksbank, Richard, Woodiwiss, Angela J

“…Although in hypertension β-adrenoreceptor activation promotes the transition from cardiac hypertrophy to pump dysfunction, the use of β-blockers is…”
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The G-308A polymorphism of the TNF-alpha gene does not predict changes in cardiac function in response to medical therapy for idiopathic dilated cardiomyopathy by Brooksbank, Richard, Badenhorst, Danelle, Sliwa, Karen, Norton, Gavin, Woodiwiss, Angela

“…The G-308A polymorphism of the tumour necrosis factor-alpha (TNF-alpha) gene, a variant that influences TNF-alpha transcription, may contribute to…”
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Systolic Cardiac Dysfunction in Pathological but Not Exercise-Induced Hypertrophy Despite Comparable Degrees of Cardiac Dilatation: 2291 by Woodiwiss, Angela J., Anamourlis, Chris, Badenhorst, Danelle, Norton, Gavin R., Thomas, D. Paul

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Functional variants of the angiotensinogen gene determine antihypertensive responses to angiotensin-converting enzyme inhibitors in subjects of African origin by Woodiwiss, Angela J, Nkeh, Benedicta, Samani, Nilesh J, Badenhorst, Danelle, Maseko, Muzi, Tiago, Armindo D, Candy, Geoffrey P, Libhaber, Elena, Sareli, Pinhas, Brooksbank, Richard, Norton, Gavin R

“…OBJECTIVETo determine whether the response to angiotensin-converting enzyme inhibitor (ACEI) monotherapy in subjects of African origin is determined by genetic…”
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β-Adrenergic Activation Initiates Chamber Dilatation in Concentric Hypertrophy by Badenhorst, Danelle, Veliotes, Demetri, Maseko, Muzi, Tsotetsi, Oupa J, Brooksbank, Richard, Naidoo, Alvin, Woodiwiss, Angela J, Norton, Gavin R

“…ABSTRACT—It is uncertain whether chronic β-adrenoreceptor (β-AR)–activation in hypertension could initiate the progression from compensated left ventricular…”
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Effects of Pentoxifylline on cytokine profiles and left ventricular performance in patients with decompensated congestive heart failure secondary to idiopathic dilated by Sliwa, Karen, Woodiwiss, Angela, Candy, Geoffrey, Badenhorst, Danelle

“…Patients with severe heart failure have plasma cytokine concentrations that are more than twofold greater than those in patients with moderate heart failure…”
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T594M variant of the epithelial sodium channel β-subunit gene and hypertension in individuals of African ancestry in South Africa by Nkeh, Benedicta, Samani, Nilesh J, Badenhorst, Danelle, Libhaber, Elena, Sareli, Pinhas, Norton, Gavin R, Woodiwiss, Angela J

“…The T594M variant of the β-subunit of the sodium epithelial channel (ENaC) gene may contribute to hypertension in individuals of African origin. A case-control…”
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Chronic beta-adrenoreceptor activation increases cardiac cavity size through chamber remodeling and not via modifications in myocardial material properties by Gibbs, Mark, Veliotes, Demetri G A, Anamourlis, Christopher, Badenhorst, Danelle, Osadchii, Oleg, Norton, Gavin R, Woodiwiss, Angela J

“…Chronic beta-adrenoreceptor (beta-AR) activation increases left ventricular (LV) cavity size by promoting a rightward shift in LV diastolic pressure-volume…”
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β1- and α2c-adrenoreceptor variants as predictors of clinical aspects of dilated cardiomyopathy in people of African ancestry by Woodiwiss, Angela J, Badenhorst, Danelle, Brooksbank, Richard, Sareli, Pinhas, Norton, Gavin R, Sliwa, Karen, Essop, Rafique

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ß1- and α2c-adrenoreceptor variants as predictors of clinical aspects of dilated cardiomyopathy in people of African ancestry : cardiovascular topics by Norton, Gavin R., Sareli, Pinhas, Woodiwiss, Angela J., Essop, Rafique, Brooksbank, Richard, Sliwa, Karen, Badenhorst, Danelle

“…Background : Although the ß1-adrenoreceptor (AR) Gly389Arg and α2c-AR Del322-325 gene variants are associated with the response to ß-AR-blocker therapy,…”
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An aldosterone synthase gene variant is associated with improvement in left ventricular ejection fraction in dilated cardiomyopathy by Tiago, Armindo D., Badenhorst, Danelle, Skudicky, Daniel, Woodiwiss, Angela J., Candy, Geoffrey P., Brooksbank, Richard, Sliwa, Karen, Sareli, Pinhas, Norton, Gavin R.

“…Objective: To assess whether renin–angiotensin–aldosterone (RAA) system gene polymorphisms shown to be associated with alterations in the activity of the…”
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The relationship between the nitric oxide synthase gene and the risk of hypertension defined according to ambulatory blood pressures : NO synthase gene and ambulatory BP by Libhaber, Elena, Brooksbank, Richard, Norton, Gavin R., Badenhorst, Danelle, Candy, Geoffrey, Woodiwiss, Angela J., Sareli, Pinhas

“…Although nitric oxide (NO) plays an important role in blood pressure (BP) control, whether variation of genes involved in regulating the synthesis of NO…”
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Impact of renin-angiotensin-aldosterone system gene variants on the severity of hypertension in patients with newly diagnosed hypertension by Tiago, Armindo D, Badenhorst, Danelle, Nkeh, Benedicta, Candy, Geoffrey P, Brooksbank, Richard, Sareli, Pinhas, Libhaber, Elena, Samani, Nilesh J, Woodiwiss, Angela J, Norton, Gavin R

“…The severity of hypertension has prognostic significance. Previous studies have assessed the relationship between renin-angiotensin-aldosterone system (RAAS)…”
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Phosphodiesterase inhibition promotes the transition from compensated hypertrophy to cardiac dilatation in rats by Anamourlis, Christopher, Badenhorst, Danelle, Gibbs, Mark, Correia, Raul, Veliotes, Demetri, Osadchii, Oleg, Norton, Gavin R, Woodiwiss, Angela J

“…The cellular signaling pathways responsible for the transition from compensated left ventricular hypertrophy (LVH) to LV dilatation (remodeling) and heart…”
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