Search Results - "Baden, Lindsey R"
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Interleukin-6 Receptor Inhibition in Covid-19 — Cooling the Inflammatory Soup
Published in The New England journal of medicine (22-04-2021)“…Viruses cannot replicate by themselves. Instead, they rely on the host for almost all their replicative functions. Similarly, many viruses are unable to cause…”
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Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine
Published in The New England journal of medicine (04-02-2021)“…Two injections of mRNA-1273, a lipid nanoparticle–encapsulated mRNA-based vaccine produced in collaboration with the NIAID that encodes the SARS-CoV-2 spike…”
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Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial
Published in Science (American Association for the Advancement of Science) (07-01-2022)“…In the coronavirus efficacy (COVE) phase 3 clinical trial, vaccine recipients were assessed for neutralizing and binding antibodies as correlates of risk for…”
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Persistence and Evolution of SARS-CoV-2 in an Immunocompromised Host
Published in The New England journal of medicine (03-12-2020)“…This letter describes an immunocompromised patient who had persistent infection with SARS-CoV-2 over a period of months, despite several courses of remdesivir…”
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SARS-CoV-2 Omicron Variant Neutralization after mRNA-1273 Booster Vaccination
Published in The New England journal of medicine (17-03-2022)“…Neutralization of the omicron variant was assessed in serum samples obtained from persons who had received an mRNA-1273 booster. After the standard two-dose…”
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Antinucleocapsid Antibodies After SARS-CoV-2 Infection in the Blinded Phase of the Randomized, Placebo-Controlled mRNA-1273 COVID-19 Vaccine Efficacy Clinical Trial
Published in Annals of internal medicine (01-09-2022)“…Immunoassays for determining past SARS-CoV-2 infection have not been systematically evaluated in vaccinated persons in comparison with unvaccinated persons. To…”
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American College of Rheumatology Guidance for the Management of Rheumatic Disease in Adult Patients During the COVID‐19 Pandemic: Version 3
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-02-2021)“…Objective To provide guidance to rheumatology providers on the management of adult rheumatic disease in the context of the coronavirus disease 2019 (COVID‐19)…”
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Bacteriophage treatment of disseminated cutaneous Mycobacterium chelonae infection
Published in Nature communications (03-05-2022)“…Mycobacterium chelonae is a rare cause of chronic disseminated cutaneous infections in immunocompromised patients. Multidrug-resistant M. chelonae infections…”
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Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology
Published in Cell (05-11-2015)“…While antibody titers and neutralization are considered the gold standard for the selection of successful vaccines, these parameters are often inadequate…”
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Audio Interview: Ending the Covid-19 Emergency
Published in The New England journal of medicine (11-05-2023)“…In this audio interview conducted on May 8, 2023, the editors assess what the end of the WHO and CDC emergency declarations will mean…”
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American College of Rheumatology Guidance for the Management of Rheumatic Disease in Adult Patients During the COVID‐19 Pandemic: Version 2
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-09-2020)“…Objective To provide guidance to rheumatology providers on the management of adult rheumatic disease in the context of the coronavirus disease 2019 (COVID‐19)…”
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Audio Interview: What’s Gone Right in Our Battle against Covid-19
Published in The New England journal of medicine (25-11-2021)“…In this audio interview conducted on November 23, 2021, the editors discuss a string of successes against Covid-19, as well as a new study of the immunity…”
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Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization
Published in The Journal of immunology (1950) (01-12-2016)“…Due to functionally distinct cell-mediated immunity, newborns and infants are highly susceptible to infection with intracellular pathogens. Indeed, neonatal…”
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A Breath Fungal Secondary Metabolite Signature to Diagnose Invasive Aspergillosis
Published in Clinical infectious diseases (15-12-2014)“…Background. Invasive aspergillosis (IA) remains a leading cause of mortality in immunocompromised patients, in part due to the difficulty of diagnosing this…”
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Diagnostic Performance of the (1→3)-β-d-Glucan Assay for Invasive Fungal Disease
Published in Clinical infectious diseases (01-12-2009)“…Background.Diagnosis of invasive fungal disease (IFD) is challenging, and it remains a significant cause of morbidity and mortality in immunocompromised…”
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Randomized, double-blind trial of fluconazole versus voriconazole for prevention of invasive fungal infection after allogeneic hematopoietic cell transplantation
Published in Blood (09-12-2010)“…Invasive fungal infection (IFI) is a serious threat after allogeneic hematopoietic cell transplant (HCT). This multicenter, randomized, double-blind trial…”
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Longitudinal SARS-CoV-2 Nucleocapsid Antibody Kinetics, Seroreversion, and Implications for Seroepidemiologic Studies
Published in Emerging infectious diseases (01-09-2022)“…Given widespread use of spike antibody in generating coronavirus disease vaccines, SARS-CoV-2 nucleocapsid antibodies are increasingly used to indicate…”
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Initial analysis of viral dynamics and circulating viral variants during the mRNA-1273 Phase 3 COVE trial
Published in Nature medicine (01-04-2022)“…The mRNA-1273 vaccine for coronavirus disease 2019 (COVID-19) demonstrated 93.2% efficacy in reduction of symptomatic severe acute respiratory syndrome…”
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Molecular Methods To Improve Diagnosis and Identification of Mucormycosis
Published in Journal of Clinical Microbiology (01-06-2011)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Three-month antibody persistence of a bivalent Omicron-containing booster vaccine against COVID-19
Published in Nature communications (23-08-2023)“…We previously presented day 29 interim safety and immunogenicity results from a phase 2/3 study (NCT04927065) comparing the Omicron-BA.1-containing bivalent…”
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