Search Results - "Bade, Rory"
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Longitudinal Molecular Profiling of Circulating Tumor Cells in Metastatic Renal Cell Carcinoma
Published in Journal of clinical oncology (01-11-2022)“…Liquid biopsies in metastatic renal cell carcinoma (mRCC) provide a unique approach to understand the molecular basis of treatment response and resistance…”
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Versatile exclusion-based sample preparation platform for integrated rare cell isolation and analyte extraction
Published in Lab on a chip (06-11-2018)“…Rare cell populations provide a patient-centric tool to monitor disease treatment, response, and resistance. However, understanding rare cells is a complex…”
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Development and initial clinical testing of a multiplexed circulating tumor cell assay in patients with clear cell renal cell carcinoma
Published in Molecular oncology (01-09-2021)“…Although therapeutic options for patients with advanced renal cell carcinoma (RCC) have increased in the past decade, no biomarkers are yet available for…”
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Analytical validation and initial clinical testing of quantitative microscopic evaluation for PD-L1 and HLA I expression on circulating tumor cells from patients with non-small cell lung cancer
Published in Biomarker research (25-04-2022)“…PD-L1 expression in non-small cell lung cancer (NSCLC) predicts response to immune checkpoint blockade, however is an imperfect biomarker given tumor…”
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A clinical-grade liquid biomarker detects neuroendocrine differentiation in prostate cancer
Published in The Journal of clinical investigation (01-11-2022)“…BackgroundNeuroendocrine prostate cancer (NEPC) is an aggressive subtype, the presence of which changes the prognosis and management of metastatic prostate…”
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Neighborhood Disadvantage, Insurance Status, and Molecular Profiling of Patients with Acute Myeloid Leukemia
Published in Blood (15-11-2022)Get full text
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Neighborhood disadvantage, insurance status, and molecular profiling of patients with acute myeloid leukemia
Published in Leukemia research (01-08-2023)“…Next-generation sequencing (NGS) is important for prognostication and determining eligibility for targeted therapies in acute myeloid leukemia (AML). The use…”
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Single cell phenotyping of PDL1 and HLA1 on circulating tumor cells (CTC) in clear cell renal cell carcinoma (ccRCC) on systemic treatment with immunotherapy (IO) and vascular endothelial growth factor receptor tyrosine kinase inhibitors (TKI)
Published in Journal of clinical oncology (20-02-2022)“…Abstract only 381 Background: Single agent or combination regimens using different IO and TKI agents have dramatically improved survival of patients (pt) with…”
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Prognostic value of integrated liquid biopsies in patients (pts) with metastatic urothelial cancer (mUC)
Published in Journal of clinical oncology (20-02-2023)“…547 Background: Despite recent therapeutic advancements for patients with mUC, including checkpoint inhibitors (CPIs), anti-FGFR and antibody-drug conjugates…”
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Clinical correlation of circulating tumor cell (CTC) PD-L1 and HLA I expression in metastatic renal cell carcinoma (mRCC) using exclusion-based sample preparation technology
Published in Journal of clinical oncology (20-02-2020)“…Abstract only 721 Background: Despite therapeutic advancement in Vascular endothelial growth factor receptor (VEGF-R) tyrosine kinase inhibitors (TKIs) and…”
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Abstract B40: Analytical validation and initial clinical utility of multianalyte transcriptomic biomarker profiling of circulating tumor cells using automated exclusion-based sample preparation technology
Published in Clinical cancer research (01-06-2020)“…The efficacy of androgen receptor (AR) signaling inhibitors (ARSIs) in prostate cancer is limited by both de novo and acquired resistance. Two well-described…”
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A clinical-grade liquid biomarker detects neuroendocrine differentiation in prostate cancer
Published in The Journal of clinical investigation (01-11-2022)“…BACKGROUND. Neuroendocrine prostate cancer (NEPC) is an aggressive subtype, the presence of which changes the prognosis and management of metastatic prostate…”
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Abstract 4585: Development of multi-marker capture and analysis of circulating tumor cells in renal cell carcinoma
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Purpose: Circulating biomarkers are an emerging tool to monitor treatment response and the emergence of resistant phenotypes. However, studies of circulating…”
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Abstract B066: Analytical validation of a multiplexed CTC-mRNA assay for androgen receptor pathway inhibitors
Published in Clinical cancer research (13-11-2024)“…Introduction: Androgen receptor pathway inhibitors (ARPIs) have been shown to improve survival for men with metastatic prostate cancer, however, the use of 2nd…”
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Abstract 5122: Identification of PD-L1 expression on circulating tumor cells as a prognostic indicator in prospective clinical trial, OMNIVORE
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Despite recent therapeutic advances for patients with renal cell carcinoma (RCC) with immunotherapies, alone or in combination with VEGF tyrosine kinase…”
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