Search Results - "Badachhape, Andrew A"

Rational Design of a Self‐Assembling High Performance Organic Nanofluorophore for Intraoperative NIR‐II Image‐Guided Tumor Resection of Oral Cancer by Sun, Xianwei, Chintakunta, Praveen Kumar, Badachhape, Andrew A., Bhavane, Rohan, Lee, Huan‐Jui, Yang, David S., Starosolski, Zbigniew, Ghaghada, Ketan B., Vekilov, Peter G., Annapragada, Ananth V., Tanifum, Eric A.

“…The first line of treatment for most solid tumors is surgical resection of the primary tumor with adequate negative margins. Incomplete tumor resections with…”
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Intratumoral nanofluidic system enhanced tumor biodistribution of PD-L1 antibody in triple-negative breast cancer by Liu, Hsuan-Chen, Capuani, Simone, Badachhape, Andrew A, Di Trani, Nicola, Davila Gonzalez, Daniel, Vander Pol, Robin S, Viswanath, Dixita I, Saunders, Shani, Hernandez, Nathanael, Ghaghada, Ketan B, Chen, Shu-Hsia, Nance, Elizabeth, Annapragada, Ananth V, Chua, Corrine Ying Xuan, Grattoni, Alessandro

“…Immune checkpoint inhibitors (ICI), pembrolizumab and atezolizumab, were recently approved for treatment-refractory triple-negative breast cancer (TNBC), where…”
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Mechanical properties of porcine brain tissue in vivo and ex vivo estimated by MR elastography by Guertler, Charlotte A., Okamoto, Ruth J., Schmidt, John L., Badachhape, Andrew A., Johnson, Curtis L., Bayly, Philip V.

“…The mechanical properties of brain tissue in vivo determine the response of the brain to rapid skull acceleration. These properties are thus of great interest…”
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Advances in nanoprobes for molecular MRI of Alzheimer's disease by Parekh, Parag, Badachhape, Andrew A., Tanifum, Eric A., Annapragada, Ananth V., Ghaghada, Ketan B.

“…Alzheimer's disease is the most common cause of dementia and a leading cause of mortality in the elderly population. Diagnosis of Alzheimer's disease has…”
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Nanoparticle Contrast-enhanced MRI for Visualization of Retroplacental Clear Space Disruption in a Mouse Model of Placental Accreta Spectrum (PAS) by Badachhape, Andrew A., Bhandari, Prajwal, Devkota, Laxman, Srivastava, Mayank, Tanifum, Eric A., George, Verghese, Fox, Karin A., Yallampalli, Chandrasekhar, Annapragada, Ananth V., Ghaghada, Ketan B.

“…Prior preclinical studies established the utility of liposomal nanoparticle blood-pool contrast agents in visualizing the retroplacental clear space (RPCS), a…”
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Relationships between scalp, brain, and skull motion estimated using magnetic resonance elastography by Badachhape, Andrew A., Okamoto, Ruth J., Johnson, Curtis L., Bayly, Philip V.

“…The objective of this study was to characterize the relationships between motion in the scalp, skull, and brain. In vivo estimates of motion transmission from…”
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A novel treatment strategy utilizing panobinostat for high-risk and treatment-refractory hepatoblastoma by Espinoza, Andres F., Patel, Roma H., Patel, Kalyani R., Badachhape, Andrew A., Whitlock, Richard, Srivastava, Rohit K., Govindu, Saiabhiroop R., Duong, Ashley, Kona, Abhishek, Kureti, Pavan, Armbruster, Bryan, Kats, Dina, Srinivasan, Ramakrishnan R., Dobrolecki, Lacey E., Yu, Xinjian, Najaf Panah, Mohammad J., Zorman, Barry, Sarabia, Stephen F., Urbicain, Martin, Major, Angela, Bissig, Karl-Dimiter, Keller, Charles, Lewis, Michael T., Heczey, Andras, Sumazin, Pavel, López-Terrada, Dolores H., Woodfield, Sarah E., Vasudevan, Sanjeev A.

“…Patients with metastatic, treatment-refractory, and relapsed hepatoblastoma (HB) have survival rates of less than 50% due to limited treatment options. To…”
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Nanoparticle Contrast-enhanced T1-Mapping Enables Estimation of Placental Fractional Blood Volume in a Pregnant Mouse Model by Badachhape, Andrew A., Devkota, Laxman, Stupin, Igor V., Sarkar, Poonam, Srivastava, Mayank, Tanifum, Eric A., Fox, Karin A., Yallampalli, Chandrasekhar, Annapragada, Ananth V., Ghaghada, Ketan B.

“…Non-invasive methods for estimating placental fractional blood volume (FBV) are of great interest for characterization of vascular perfusion in placentae…”
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Pre-clinical dose-ranging efficacy, pharmacokinetics, tissue biodistribution, and toxicity of a targeted contrast agent for MRI of amyloid deposition in Alzheimer’s disease by Badachhape, Andrew A., Working, Peter K., Srivastava, Mayank, Bhandari, Prajwal, Stupin, Igor V., Devkota, Laxman, Tanifum, Eric A., Annapragada, Ananth V., Ghaghada, Ketan B.

“…In these preclinical studies, we describe ADx-001 , an Aβ-targeted liposomal macrocyclic gadolinium (Gd) imaging agent, for MRI of amyloid plaques. The…”
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The Relationship of Three-Dimensional Human Skull Motion to Brain Tissue Deformation in Magnetic Resonance Elastography Studies by Badachhape, Andrew A, Okamoto, Ruth J, Durham, Ramona S, Efron, Brent D, Nadell, Sam J, Johnson, Curtis L, Bayly, Philip V

“…In traumatic brain injury (TBI), membranes such as the dura mater, arachnoid mater, and pia mater play a vital role in transmitting motion from the skull to…”
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Pre-clinical magnetic resonance imaging of retroplacental clear space throughout gestation by Badachhape, Andrew A., Kumar, Aarav, Ghaghada, Ketan B., Stupin, Igor V., Srivastava, Mayank, Devkota, Laxman, Starosolski, Zbigniew, Tanifum, Eric A., George, Verghese, Fox, Karin A., Yallampalli, Chandrasekhar, Annapragada, Ananth V.

“…Visualization of the retroplacental clear space (RPCS) may provide critical insight into the development of abnormally invasive placenta (AIP). In this…”
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A Hyperfluorinated Hydrophilic Molecule for Aqueous 19F MRI Contrast Media by Annapragada, Ananth V., Romero, Jonathan, Ghaghada, Ketan B., Badachhape, Andrew A., Ngwa, Conelius, Devkota, Laxman, Tanifum, Eric A., Pautler, Robia G.

“…Fluorine-19 (19F) magnetic resonance imaging (MRI) has the potential for a wide range of in vivo applications but is limited by lack of flexibility in…”
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Molecular Signatures of Alzheimer’s Disease (AD) in SARS‐Cov‐2 Infected Mouse Brains by Parekh, Parag A, Badachhape, Andrew A, Menon, Renuka, Ghaghada, Ketan, Ronca, Shannon E, Annapragada, Ananth

“…Background COVID‐19 is primarily a respiratory syndrome caused by SARS‐CoV‐2 infection, however, a third of COVID‐19 patients report post‐acute neurological…”
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MR Nano‐Radiomics for Detection of Amyloid Plaques in Alzheimer’s Disease by Starosolski, Zbigniew, Badachhape, Andrew A, Devkota, Laxman, Srivastava, Mayank, Tanifum, Eric, Annapragada, Ananth, Ghaghada, Ketan

“…Background Amyloid plaques are a pathological hallmark of Alzheimer’s disease (AD). In a recent pre‐clinical study, we showed an amyloid‐targeted liposomal…”
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MRI of Neuroinflammation Using a Folate Receptor β‐Targeted Nanoparticle Contrast Agent by Badachhape, Andrew A, Parekh, Parag A, Bhandari, Prajwal, Menon, Renuka, Bhavane, Rohan, Srivastava, Mayank, Tanifum, Eric, Annapragada, Ananth, Ghaghada, Ketan

“…Background Neuroinflammation plays an important role in Alzheimer’s disease (AD) pathogenesis and disease progression leading to cognitive decline. Current…”
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Molecular MRI Identifies Sexually Dimorphic AD Pathology in 3x Tg‐AD Mice by Parekh, Parag A, Badachhape, Andrew A, Menon, Renuka, Bhavane, Rohan, Srivastava, Mayank, Sun, Xianwei, Bhandari, Prajwal, Devkota, Laxman, Tanifum, Eric, Ghaghada, Ketan, Devaraj, Sridevi, Annapragada, Ananth

“…Background Women exhibit higher prevalence of Alzheimer’s disease (AD) with faster cognitive decline compared to men, but the mechanisms of this dimorphism…”
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Nanoparticle Contrast-enhanced MRI for Visualization of Retroplacental Clear Space Disruption in a Mouse Model of Placenta Accreta Spectrum (PAS) by Badachhape, Andrew A., Bhandari, Prajwal, Devkota, Laxman, Srivastava, Mayank, Tanifum, Eric A., George, Verghese, Fox, Karin A., Yallampalli, Chandrasekhar, Annapragada, Ananth V., Ghaghada, Ketan B.

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A Hyperfluorinated Hydrophilic Molecule for Aqueous 19 F MRI Contrast Media by Tanifum, Eric A., Devkota, Laxman, Ngwa, Conelius, Badachhape, Andrew A., Ghaghada, Ketan B., Romero, Jonathan, Pautler, Robia G., Annapragada, Ananth V.

“…Fluorine-19 ( 19 F) magnetic resonance imaging (MRI) has the potential for a wide range of in vivo applications but is limited by lack of flexibility in…”
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Characterization of Structural Dynamics of the Human Head Using Magnetic Resonance Elastography by Badachhape, Andrew A

“…In traumatic brain injury (TBI), the skull-brain interface, composed of three meningeal layers: the dura mater, arachnoid mater, and pia mater, along with…”
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A Hyperfluorinated Hydrophilic Molecule for Aqueous 19 F MRI Contrast Media by Tanifum, Eric A, Devkota, Laxman, Ngwa, Conelius, Badachhape, Andrew A, Ghaghada, Ketan B, Romero, Jonathan, Pautler, Robia G, Annapragada, Ananth V

“…Fluorine-19 ( F) magnetic resonance imaging (MRI) has the potential for a wide range of applications but is limited by lack of flexibility in exogenous probe…”
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