Search Results - "Bacová, Zuzana"
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Molecular Mechanisms of Oxytocin Signaling at the Synaptic Connection
Published in Neural plasticity (01-01-2018)“…Aberrant regulation of oxytocin signaling is associated with the etiology of neurodevelopmental disorders. Synaptic dysfunctions in neurodevelopmental…”
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Effect of Haloperidol and Olanzapine on Hippocampal Cells’ Proliferation in Animal Model of Schizophrenia
Published in International journal of molecular sciences (12-07-2022)“…Aberrant neurogenesis in the subventricular zone (SVZ) and hippocampus (HIP) contributes to schizophrenia pathogenesis. Haloperidol (HAL) and olanzapine (OLA),…”
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The impact of oxytocin on neurite outgrowth and synaptic proteins in Magel2‐deficient mice
Published in Developmental biology (01-05-2021)“…Oxytocin contributes to the regulation of cytoskeletal and synaptic proteins and could, therefore, affect the mechanisms of neurodevelopmental disorders,…”
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Shank3 deficiency alters midbrain GABAergic neuron morphology, GABAergic markers and synaptic activity in primary striatal neurons
Published in Molecular brain (27-09-2024)“…Abnormalities in gamma-aminobutyric acid (GABA)ergic neurotransmission play a role in the pathogenesis of autism, although the mechanisms responsible for…”
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Mini review of molecules involved in altered postnatal neurogenesis in autism
Published in International journal of neuroscience (13-10-2023)“…The neurobiology of autism is complex, but emerging research points to potential abnormalities and alterations in neurogenesis. The aim of the present review…”
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Abnormal neuronal morphology and altered synaptic proteins are restored by oxytocin in autism-related SHANK3 deficient model
Published in Molecular and cellular endocrinology (01-12-2020)“…Oxytocin has been suggested as a potential therapeutic agent in autism and other neuropsychiatric conditions. Although, the link between the deficit in “SH3…”
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Oxytocin, GABA, and dopamine interplay in autism
Published in Endocrine regulations (Bratislava) (01-01-2024)“…Oxytocin plays an important role in brain development and is associated with various neurotransmitter systems in the brain. Abnormalities in the production,…”
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Effects of antipsychotics, haloperidol and olanzapine, on the expression of apoptosis-related genes in mouse mHippoE-2 cells and rat hippocampus
Published in Endocrine regulations (Bratislava) (01-01-2023)“…Modified levels of pro- (caspase3, Bax) and anti-apoptotic (Bcl-2) regulatory proteins have been detected in certain brain areas of schizophrenic patients…”
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Shank3 Deficiency is Associated With Altered Profile of Neurotransmission Markers in Pups and Adult Mice
Published in Neurochemical research (01-12-2021)“…Alterations in the balance between excitation and inhibition, especially in the brain’s critical developmental periods, are considered an integral part of the…”
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The role of selected postsynaptic scaffolding proteins at glutamatergic synapses in autism-related animal models
Published in Journal of integrative neuroscience (30-12-2021)“…Pathological changes in synapse formation, plasticity, and development are caused by altered trafficking and assembly of postsynaptic scaffolding proteins at…”
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Gene expression levels of DNA methyltransferase enzymes in Shank3-deficient mouse model of autism during early development
Published in Endocrine regulations (Bratislava) (01-10-2021)“…The balance between DNA methylation and demethylation is crucial for the brain development. Therefore, alterations in the expression of enzymes controlling DNA…”
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The Role of Hypothalamic Neuropeptides in Neurogenesis and Neuritogenesis
Published in Neural plasticity (01-01-2016)“…The hypothalamus is a source of neural progenitor cells which give rise to different populations of specialized and differentiated cells during brain…”
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Photodynamic therapy of multidrug resistant leukemic murine cells by 3,6-bis(alkylthiourea)acridine hydrochlorides
Published in Neoplasma (01-11-2021)“…Efforts to overcome multidrug resistance in cancer have led to the development of several novel strategies including photodynamic therapy (PDT). PDT is based…”
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Neonatal manipulation of oxytocin prevents lipopolysaccharide-induced decrease in gene expression of growth factors in two developmental stages of the female rat
Published in Neuropeptides (Edinburgh) (01-10-2014)“…Highlights • Neonatal oxytocin did not prevent decrease of body weight in LPS treated animals. • Oxytocin increased BDNF mRNA in 21-day and 2-month old rats of…”
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Neuronal morphology alterations in autism and possible role of oxytocin
Published in Endocrine regulations (Bratislava) (01-01-2019)“…Current understanding of the neuroanatomical abnormalities in autism includes gross anatomical changes in several brain areas and microstructural alterations…”
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Oxytocin Receptor Ligands Induce Changes in Cytoskeleton in Neuroblastoma Cells
Published in Journal of molecular neuroscience (01-07-2013)“…Aim of the present study was to evaluate effects of ligands of oxytocin receptors on gene expression of neurofilament proteins (nestin and…”
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OCCURRENCES OF NEOGENE VOLCANIC GLASS IN THE EASTERN SLOVAKIA – RAW MATERIAL SOURCE FOR THE STONE INDUSTRY
Published in Anthropologie (Brno) (01-01-2017)“…In Eastern Slovakia obsidians were used most extensively during the Late Palaeolithic and Neolithic. Natural occurrences of obsidian are linked with products…”
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Cell Swelling-induced Insulin Secretion from INS-1E Cells is Inhibited by Extracellular Ca2+ and is Tetanus Toxin Resistant
Published in Cellular physiology and biochemistry (01-01-2010)“…Cell swelling-induced insulin secretion represents an alternative pathway of stimulation of insulin secretion. INS-1E rat tumor beta cells do not release…”
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Resveratrol Inhibits Electrical Activity and Insulin Release from Insulinoma Cells by Block of Voltage-Gated Ca2+ Channels and Swelling-Dependent Cl- Currents
Published in Cellular physiology and biochemistry (01-01-2008)“…The phytostilbene resveratrol (RV) improves the metabolic state in animal models by increasing the insulin responsiveness of tissues and there is evidence that…”
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Mechanism of Ethanol-Induced Insulin Secretion from INS-1 and INS-1E Tumor Cell Lines
Published in Cellular physiology and biochemistry (01-01-2009)“…Alcohol causes reactive hypoglycemia by attenuating the release of counter regulatory hormones, redistribution of pancreatic blood flow and direct stimulation…”
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