Search Results - "Bacot, Sandrine"

Molecular imaging of liver inflammation using an anti-VCAM-1 nanobody by Nachit, Maxime, Montemagno, Christopher, Clerc, Romain, Ahmadi, Mitra, Briand, François, Bacot, Sandrine, Devoogdt, Nick, Serdjebi, Cindy, Ghezzi, Catherine, Sulpice, Thierry, Broisat, Alexis, Leclercq, Isabelle A., Perret, Pascale

“…To date, a biopsy is mandatory to evaluate parenchymal inflammation in the liver. Here, we evaluated whether molecular imaging of vascular cell adhesion…”
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A single-domain antibody for the detection of pathological Tau protein in the early stages of oligomerization by De Leiris, Nicolas, Perret, Pascale, Lombardi, Charlotte, Gözel, Bülent, Chierici, Sabine, Millet, Philippe, Debiossat, Marlène, Bacot, Sandrine, Tournier, Benjamin B, Chames, Patrick, Lenormand, Jean-Luc, Ghezzi, Catherine, Fagret, Daniel, Moulin, Marcelle

“…Soluble oligomeric forms of Tau protein have emerged as crucial players in the propagation of Tau pathology in Alzheimer's disease (AD). Our objective is to…”
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Biodistribution, Stability, and Blood Distribution of the Cell Penetrating Peptide Maurocalcine in Mice by Perret, Pascale, Ahmadi, Mitra, Riou, Laurent, Bacot, Sandrine, Pecher, Julien, Poillot, Cathy, Broisat, Alexis, Ghezzi, Catherine, De Waard, Michel

“…Maurocalcine (MCa) is the first natural cell penetrating peptide to be discovered in animal venom. In addition to the fact that it represents a potent vector…”
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TrisOxine abiotic siderophores for technetium complexation: radiolabeling and biodistribution studies by Leenhardt, Julien, Biguet Petit Jean, Alexandre, Raes, Florian, N’Guessan, Emilien, Debiossat, Marlène, André, Clémence, Bacot, Sandrine, Ahmadi, Mitra, de Leiris, Nicolas, Djaileb, Loïc, Ghezzi, Catherine, Brunet, Marie-Dominique, Broisat, Alexis, Perret, Pascale, du Moulinet d’Hardemare, Amaury

“…Background Despite the development of positron emission tomography (PET), single photon emission computed tomography (SPECT) still accounts for around 80% of…”
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Evidence for in situ ethanolamine phospholipid adducts with hydroxy-alkenals by Bacot, Sandrine, Bernoud-Hubac, Nathalie, Chantegrel, Bernard, Deshayes, Christian, Doutheau, Alain, Ponsin, Gabriel, Lagarde, Michel, Guichardant, Michel

“…Hydroxy-alkenals, such as 4-hydroxy-2(E)-nonenal (4-HNE; from n-6 fatty acids), are degradation products of fatty acid hydroperoxides, including those…”
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Covalent binding of hydroxy-alkenals 4-HDDE, 4-HHE, and 4-HNE to ethanolamine phospholipid subclasses by Bacot, Sandrine, Bernoud-Hubac, Nathalie, Baddas, Naima, Chantegrel, Bernard, Deshayes, Christian, Doutheau, Alain, Lagarde, Michel, Guichardant, Michel

“…Lipid oxidation is implicated in a wide range of pathophysiogical disorders, and leads to reactive compounds such as fatty aldehydes, of which the most well…”
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Validation of HPLC and TLC analytical methods to determine radiochemical purity of 99mTc-cAbVCAM1-5, a new experimental radiotracer by Mutin, Juliette, Orhon, Pauline, Choisnard, Luc, Lassiaz, Maxime, Bacot, Sandrine, Ahmadi, Mitra, De Leiris, Nicolas, Djaileb, Loic, Broisat, Alexis, Ghezzi, Catherine, Bedouch, Pierrick, Brunet, Marie-Dominique, Leenhardt, Julien

“…Cardiovascular diseases, including fatal myocardial infarctions from atheromatous plaques, are the primary global mortality cause. Detecting stenotic…”
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Validation of HPLC and TLC analytical methods to determine radiochemical purity of 99m Tc-cAbVCAM1-5, a new experimental radiotracer by Mutin, Juliette, Orhon, Pauline, Choisnard, Luc, Lassiaz, Maxime, Bacot, Sandrine, Ahmadi, Mitra, De Leiris, Nicolas, Djaileb, Loic, Broisat, Alexis, Ghezzi, Catherine, Bedouch, Pierrick, Brunet, Marie-Dominique, Leenhardt, Julien

“…Cardiovascular diseases, including fatal myocardial infarctions from atheromatous plaques, are the primary global mortality cause. Detecting stenotic…”
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Preclinical Evaluation of Mesothelin-Specific Ligands for SPECT Imaging of Triple-Negative Breast Cancer by Montemagno, Christopher, Bacot, Sandrine, Ahmadi, Mitra, Kerfelec, Brigitte, Baty, Daniel, Debiossat, Marlene, Soubies, Audrey, Perret, Pascale, Riou, Laurent, Fagret, Daniel, Broisat, Alexis, Ghezzi, Catherine

“…Mesothelin is a cell-surface glycoprotein restricted to mesothelial cells overexpressed in several types of cancer, including triple-negative breast cancer not…”
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In Vivo Biodistribution and Efficacy Evaluation of NeoB, a Radiotracer Targeted to GRPR, in Mice Bearing Gastrointestinal Stromal Tumor by Montemagno, Christopher, Raes, Florian, Ahmadi, Mitra, Bacot, Sandrine, Debiossat, Marlène, Leenhardt, Julien, Boutonnat, Jean, Orlandi, Francesca, Barbato, Donato, Tedesco, Mattia, Ghezzi, Catherine, Perret, Pascale, Broisat, Alexis

“…NeoB is a radiotracer targeting the gastrin-releasing peptide receptor (GRPR), a G-protein-coupled receptor expressed in various cancers. The aim of the…”
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In vivo biodistribution and efficacy evaluation of NeoBOMB1, a theranostic agent targeting GRPR, in mice bearing GastroIntestinal Stromal Tumor by Broisat, Alexis, Ahmadi, Mitra, Bacot, Sandrine, Orlandi, Francesca, Barbato, Donato, Tedesco, Mattia, Debiossat, Marlã¨ne, Perret, Pascale, Ghezzi, Catherine

“…Objectives: The gastrin-releasing peptide receptor (GRPR), also known as bombesin receptor subtype 2, is a G-protein-coupled receptor expressed in various…”
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Endothelial chimerism and vascular sequestration protect pancreatic islet grafts from antibody-mediated rejection by Chen, Chien-Chia, Pouliquen, Eric, Broisat, Alexis, Andreata, Francesco, Racapé, Maud, Bruneval, Patrick, Kessler, Laurence, Ahmadi, Mitra, Bacot, Sandrine, Saison-Delaplace, Carole, Marcaud, Marina, Van Huyen, Jean-Paul Duong, Loupy, Alexandre, Villard, Jean, Demuylder-Mischler, Sandrine, Berney, Thierry, Morelon, Emmanuel, Tsai, Meng-Kun, Kolopp-Sarda, Marie-Nathalie, Koenig, Alice, Mathias, Virginie, Ducreux, Stéphanie, Ghezzi, Catherine, Dubois, Valerie, Nicoletti, Antonino, Defrance, Thierry, Thaunat, Olivier

“…Humoral rejection is the most common cause of solid organ transplant failure. Here, we evaluated a cohort of 49 patients who were successfully grafted with…”
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Preclinical Evaluation of Mesothelin-Specific Ligands for SPECT Imaging of Triple-Negative Breast Cancer by Montemagno, Christopher, Bacot, Sandrine, Ahmadi, Mitra, Kerfelec, Brigitte, Baty, Daniel, Debiossat, Marlene, Soubies, Audrey, Perret, Pascale, Riou, Laurent M., Fagret, Daniel, Broisat, Alexis, Ghezzi, Catherine

“…Mesothelin is a cell-surface glycoprotein restricted to mesothelial cells overexpressed in several types of cancer, including triple-negative breast cancer not…”
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Abstract 330: Ezetimibe Prevents Atherogenesis Through Increased Catabolism and Fecal Excretion of LDL-cholesterol and Reduced Atherosclerotic Plaque Inflammation in Apolipoprotein E Knock-out Mice Fed a Paigen Diet by Briand, Francois, Dumas, Laurent, Broisat, Alexis, Ahmadi, Mitra, Bacot, Sandrine, Devoogdt, Nick, Riou, Laurent, Ghezzi, Catherine, Sulpice, Thierry

“…Abstract only Background: Intestinal cholesterol absorption inhibitor ezetimibe (EZE) added to a statin therapy has demonstrated benefits in the IMPROVE-IT…”
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Evaluation of Antiatherogenic Properties of Ezetimibe Using ^sup 3^H-Labeled Low-Density-Lipoprotein Cholesterol and ^sup 99m^Tc-cAbVCAM1-5 SPECT in ApoE-/- Mice Fed the Paigen Diet by Dumas, Laurent S, Briand, François, Clerc, Romain, Brousseau, Emmanuel, Montemagno, Christopher, Ahmadi, Mitra, Bacot, Sandrine, Soubies, Audrey, Perret, Pascale, Riou, Laurent M, Devoogdt, Nick, Lahoutte, Tony, Barone-Rochette, Gilles, Fagret, Daniel, Ghezzi, Catherine, Sulpice, Thierry, Broisat, Alexis

“…The addition of ezetimibe, an intestinal cholesterol absorption inhibitor, to statin therapy has recently shown clinical benefits in the Improved Reduction of…”
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Quantitative evaluation of the cell penetrating properties of an iodinated Tyr-l-maurocalcine analog by Tisseyre, Céline, Ahmadi, Mitra, Bacot, Sandrine, Dardevet, Lucie, Perret, Pascale, Ronjat, Michel, Fagret, Daniel, Usson, Yves, Ghezzi, Catherine, De Waard, Michel

“…L-Maurocalcine (L-MCa) is the first reported animal cell-penetrating toxin. Characterizing its cell penetration properties is crucial considering its potential…”
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Endothelial chimerism and vascular sequestration protect pancreatic islet grafts from antibody-mediated rejection by Chen, Chien-Chia, Pouliquen, Eric, Broisat, Alexis, Andreata, Francesco, Racape, Maud, Bruneval, Patrick, Kessler, Laurence, Ahmadi, Mitra, Bacot, Sandrine, Saison-Delaplace, Carole, Marcaud, Marina, Van Huyen, Jean-Paul Duong, Loupy, Alexandre, Villard, Jean, Demuylder-Mischler, Sandrine, Berney, Thierry, Morelon, Emmanuel, Tsai, Meng-Kun, Kolopp-Sarda, Marie-Nathalie, Koenig, Alice, Mathias, Virginie, Ducreux, Stephanie, Ghezzi, Catherine, Dubois, Valerie, Nicoletti, Antonino, Defrance, Thierry, Thaunat, Olivier

“…Humoral rejection is the most common cause of solid organ transplant failure. Here, we evaluated a cohort of 49 patients who were successfully grafted with…”
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Evaluation of Antiatherogenic Properties of Ezetimibe Using 3 H-Labeled Low-Density-Lipoprotein Cholesterol and 99m Tc-cAbVCAM1-5 SPECT in ApoE -/- Mice Fed the Paigen Diet by Dumas, Laurent S, Briand, François, Clerc, Romain, Brousseau, Emmanuel, Montemagno, Christopher, Ahmadi, Mitra, Bacot, Sandrine, Soubies, Audrey, Perret, Pascale, Riou, Laurent M, Devoogdt, Nick, Lahoutte, Tony, Barone-Rochette, Gilles, Fagret, Daniel, Ghezzi, Catherine, Sulpice, Thierry, Broisat, Alexis

“…The addition of ezetimibe, an intestinal cholesterol absorption inhibitor, to statin therapy has recently shown clinical benefits in the Improved Reduction of…”
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In Vivo Assessment of VCAM-1 Expression by SPECT/CT Imaging in Mice Models of Human Triple Negative Breast Cancer by Montemagno, Christopher, Dumas, Laurent, Cavaillès, Pierre, Ahmadi, Mitra, Bacot, Sandrine, Debiossat, Marlène, Soubies, Audrey, Djaïleb, Loic, Leenhardt, Julien, Leiris, Nicolas de, Dufies, Maeva, Pagès, Gilles, Hernot, Sophie, Devoogdt, Nick, Perret, Pascale, Riou, Laurent, Fagret, Daniel, Ghezzi, Catherine, Broisat, Alexis

“…Recent progress in breast cancer research has led to the identification of Vascular Cell Adhesion Molecule-1 (VCAM-1) as a key actor of metastatic…”
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In Vivo Assessment of VCAM-1 Expression by SPECT/CT Imaging in Mice Models of Human Triple Negative Breast Cancer by Montemagno, Christopher, Dumas, Laurent, Cavaillès, Pierre, Ahmadi, Mitra, Bacot, Sandrine, Debiossat, Marlène, Soubies, Audrey, Djaïleb, Loïc, Leenhardt, Julien, Leiris, Nicolas, Dufies, Maeva, Pagès, Gilles, Hernot, Sophie, Devoogdt, Nick, Perret, Pascale, Riou, Laurent, Fagret, Daniel, Ghezzi, Catherine, Broisat, Alexis

“…Recent progress in breast cancer research has led to the identification of Vascular Cell Adhesion Molecule-1 (VCAM-1) as a key actor of metastatic…”
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