Search Results - "Back, Jungho"

Tendon stem/progenitor cells regulate inflammation in tendon healing via JNK and STAT3 signaling by Tarafder, Solaiman, Chen, Esther, Jun, Yena, Kao, Kristy, Sim, Kun Hee, Back, Jungho, Lee, Francis Y., Lee, Chang H.

“…ABSTRACT Tendon stem/progenitor cells (TSCs) have been found in different anatomic locations and showed a promising regenerative potential. We identified a…”
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Re-appraising the potential of naringin for natural, novel orthopedic biotherapies by Yu, Kristin E., Alder, Kareme D., Morris, Montana T., Munger, Alana M., Lee, Inkyu, Cahill, Sean V., Kwon, Hyuk-Kwon, Back, JungHo, Lee, Francis Y.

“…Naringin is a naturally occurring flavonoid found in plants of the Citrus genus that has historically been used in traditional Chinese medical regimens for the…”
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Concurrent targeting of glycolysis in bacteria and host cell inflammation in septic arthritis by Kwon, Hyuk‐Kwon, Yu, Kristin E, Cahill, Sean V, Alder, Kareme D, Dussik, Christopher M, Kim, Sang‐Hun, Sharma, Lokesh, Back, Jungho, Oh, Irvin, Lee, Francis Y

“…Intracellular infiltration of bacteria into host cells complicates medical and surgical treatment of bacterial joint infections. Unlike soft tissue infections,…”
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Unique Spatial Transcriptomic Profiling of the Murine Femoral Fracture Callus: A Preliminary Report by Jiang, Will, Caruana, Dennis L, Back, Jungho, Lee, Francis Y

“…Fracture callus formation is a dynamic stage of bone activity and repair with precise, spatially localized gene expression. Metastatic breast cancer impairs…”
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Inflammatory conversion of quiescent osteoblasts by metastatic breast cancer cells through pERK1/2 aggravates cancer-induced bone destruction by Back, Jungho, Nguyen, Minh Nam, Li, Lu, Lee, Saelim, Lee, Inkyu, Chen, Fancheng, Gillinov, Lauren, Chung, Yeon-Ho, Alder, Kareme D, Kwon, Hyuk-Kwon, Yu, Kristin E, Dussik, Christopher M, Hao, Zichen, Flores, Michael J, Kim, Yoseph, Ibe, Izuchukwu K, Munger, Alana M, Seo, Sung Wook, Lee, Francis Y

“…Disruption of bone homeostasis caused by metastatic osteolytic breast cancer cells increases inflammatory osteolysis and decreases bone formation, thereby…”
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Systemic Parathyroid Hormone Enhances Fracture Healing in Multiple Murine Models of Type 2 Diabetes Mellitus by Alder, Kareme D, White, Andrew HA, Chung, Yeon‐Ho, Lee, Inkyu, Back, JungHo, Kwon, Hyuk‐Kwon, Cahill, Sean V, Hao, Zichen, Li, Lu, Chen, Fancheng, Lee, Saelim, Riedel, Matthew D, Lee, Francis Y

“…ABSTRACT Type 2 diabetes mellitus (T2DM) is a multisystemic disease that afflicts more than 415 million people globally—the incidence and prevalence of T2DM…”
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Intracellular Staphylococcus aureus in bone and joint infections: A mechanism of disease recurrence, inflammation, and bone and cartilage destruction by Alder, Kareme D., Lee, Inkyu, Munger, Alana M., Kwon, Hyuk-Kwon, Morris, Montana T., Cahill, Sean V., Back, JungHo, Yu, Kristin E., Lee, Francis Y.

“…Bone and joint infections are devastating afflictions. Although medical interventions and advents have improved their care, bone and joint infections still…”
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Enhancement of Impaired MRSA‐Infected Fracture Healing by Combinatorial Antibiotics and Modulation of Sustained Inflammation by Yu, Kristin E, Kwon, Hyuk‐Kwon, Dussik, Christopher M, Cahill, Sean V, Back, Jungho, Alder, Kareme D, Lee, Francis Y

“…ABSTRACT Fracture healing is impaired in the setting of infection, which begets protracted inflammation. The most problematic causative agent of…”
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Smoking Alters Inflammation and Skeletal Stem and Progenitor Cell Activity During Fracture Healing in Different Murine Strains by Hao, Zichen, Li, Jun, Li, Bo, Alder, Kareme D, Cahill, Sean V, Munger, Alana M, Lee, Inkyu, Kwon, Hyuk‐Kwon, Back, JungHo, Xu, Shuogui, Kang, Min‐Jong, Lee, Francis Y

“…ABSTRACT Smokers are at a higher risk of delayed union or nonunion after fracture repair. Few specific interventions are available for prevention because the…”
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Locally delivered adjuvant biofilm‐penetrating antibiotics rescue impaired endochondral fracture healing caused by MRSA infection by Cahill, Sean V., Kwon, Hyuk‐Kwon, Back, Jungho, Lee, Inkyu, Lee, Saelim, Alder, Kareme D., Hao, Zichen, Yu, Kristin E., Dussik, Christopher M., Kyriakides, Themis R., Lee, Francis Y.

“…Infection is a devastating complication following an open fracture. We investigated whether local rifampin‐loaded hydrogel can combat infection and improve…”
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Recalcitrant methicillin-resistant Staphylococcus aureus infection of bone cells: Intracellular penetration and control strategies by Yu, Kristin, Song, Lee, Kang, Hyunwoo Paco, Kwon, Hyuk-Kwon, Back, Jungho, Lee, Francis Y

“…To characterize the intracellular penetration of osteoblasts and osteoclasts by methicillin-resistant (MRSA) and the antibiotic and detergent susceptibility of…”
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Dual therapeutic targeting of intra-articular inflammation and intracellular bacteria enhances chondroprotection in septic arthritis by Kwon, Hyuk-Kwon, Lee, Inkyu, Yu, Kristin E, Cahill, Sean V, Alder, Kareme D, Lee, Saelim, Dussik, Christopher M, Back, JungHo, Choi, Jeongjoon, Song, Lee, Kyriakides, Themis R, Lee, Francis Y

“…Bacterial infections involving joints and vital organs represent a challenging clinical problem because of the two concurrent therapeutic goals of bacterial…”
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Inflammatory conversion of quiescent osteoblasts by metastatic breast cancer cells through pERK1/2 aggravates cancer-induced bone destruction by Jungho Back, Minh Nam Nguyen, Lu Li, Saelim Lee, Inkyu Lee, Fancheng Chen, Lauren Gillinov, Yeon-Ho Chung, Kareme D.Alder, Hyuk-Kwon Kwon, Kristin E.Yu, Christopher M.Dussik, Zichen Hao, Michael J.Flores, Yoseph Kim, Izuchukwu K.Ibe, Alana M.Munger, Sung Wook Seo, Francis Y.Lee

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