Search Results - "Bachoo, R."

ATM-dependent IGF-1 induction regulates secretory clusterin expression after DNA damage and in genetic instability by Goetz, E M, Shankar, B, Zou, Y, Morales, J C, Luo, X, Araki, S, Bachoo, R, Mayo, L D, Boothman, D A

“…Secretory clusterin (sCLU) is a stress-induced, pro-survival glycoprotein elevated in early-stage cancers, in particular in APC/Min-defective colon cancers…”
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DNA double-strand breaks cooperate with loss of Ink4 and Arf tumor suppressors to generate glioblastomas with frequent Met amplification by Camacho, C V, Todorova, P K, Hardebeck, M C, Tomimatsu, N, Gil del Alcazar, C R, Ilcheva, M, Mukherjee, B, McEllin, B, Vemireddy, V, Hatanpaa, K, Story, M D, Habib, A A, Murty, V V, Bachoo, R, Burma, S

“…Glioblastomas (GBM) are highly radioresistant and lethal brain tumors. Ionizing radiation (IR)-induced DNA double-strand breaks (DSBs) are a risk factor for…”
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Malignant glioma: genetics and biology of a grave matter by Maher, E A, Furnari, F B, Bachoo, R M, Rowitch, D H, Louis, D N, Cavenee, W K, DePinho, R A

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Three-dimensional visualization of microvessel architecture of whole-mount tissue by confocal microscopy by Dickie, R., Bachoo, R.M., Rupnick, M.A., Dallabrida, S.M., DeLoid, G.M., Lai, J., DePinho, R.A., Rogers, R.A.

“…The three-dimensional architecture of the nascent microvascular network is a critical determinant of vascular perfusion in the setting of regenerative growth,…”
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Epidermal growth factor receptor and Ink4a/Arf: Convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis by Bachoo, Robert M, Maher, Elizabeth A, Ligon, Keith L, Sharpless, Norman E, Chan, Suzanne S, You, Mingjian James, Tang, Yi, DeFrances, Jessica, Stover, Elizabeth, Weissleder, Ralph, Rowitch, David H, Louis, David N, DePinho, Ronald A

“…Ink4a/Arf inactivation and epidermal growth factor receptor (EGFR) activation are signature lesions in high-grade gliomas. How these mutations mediate the…”
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Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing by DePinho, Ronald A, Wong, Kwok-Kin, Maser, Richard S, Bachoo, Robert M, Menon, Jayant, Carrasco, Daniel R, Gu, Yansong, Alt, Frederick W

“…Ataxia-telangiectasia (A-T) results from the loss of ataxia-telangiectasia mutated (Atm) function and is characterized by accelerated telomere loss, genomic…”
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DNA Double-Strand Break Repair: Implications for Glioblastoma Therapy by Amancherla, K, Mukherjee, B, McEllin, B, Pichamoorthy, N, Camacho, C, Tomimatsu, N, Bachoo, R, Burma, S

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Molecular Diversity of Astrocytes with Implications for Neurological Disorders by Bachoo, Robert M., Kim, Ryung S., Ligon, Keith L., Maher, Elizabeth A., Brennan, Cameron, Billings, Nathan, Chan, Suzanne, Li, Cheng, Rowitch, David H., Wong, Wing H., DePinho, Ronald A., Cavenee, Webster K.

“…The astrocyte represents the most abundant yet least understood cell type of the CNS. Here, we use a stringent experimental strategy to molecularly define the…”
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Ectopic Expression of the Catalytic Subunit of Telomerase Protects against Brain Injury Resulting from Ischemia and NMDA-Induced Neurotoxicity by Kang, Hyo Jung, Choi, Yoon Sik, Hong, Seung-Beom, Kim, Kee-Won, Woo, Ran-Sook, Won, Seok Joon, Kim, Eun Ju, Jeon, Hee Kyung, Jo, So-Young, Kim, Tae Kook, Bachoo, Robert, Reynolds, Ian J, Gwag, Byoung Joo, Lee, Han-Woong

“…The catalytic subunit of telomerase reverse transcriptase (TERT) protects dividing cells from replicative senescence in vitro. Here, we show that expression of…”
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Synergisitic inhibition of DNA repair by combining ß-lapachone with Nu7026 as a strategy for killing primary and metastatic breast cancers by Bey, EA, Kessinger, C, Blanco, E, Bachoo, R, Williams, N, Boothman, DA

“…Abstract Abstract #3078 The primary tumors of most breast cancer patients are removed via resection or complete mastectomy. However, years after having their…”
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RADIOBIOLOGY by Gu, C., Demir, H., Joshi, K., Nakamura, Y., Yamada, R., Gupta, S., Kwon, C.-H., Chaudhury, A. R., Nakano, I., Yong, R., Yang, C., Lonser, R., Zhuang, Z., Gwak, H.-S., Jo, G. H., Bogler, O., Chwae, Y.-J., Yoo, H., Lee, S. H., Park, J. B., Burrell, K., Jelveh, S., Hill, R., Zadeh, G., Mcellin, B., Sirasanagandla, S., Mashimo, T., Nannepaja, S., Vemireddy, V., Burma, S., Bachoo, R.

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Comparative study of testicular tissue reparative peculiarities on the model of bilateral abdominal cryptorchism in young and mature animals by I D Kirpatovskiy, D L Titarov, V A Bychkov, E K Zhamynchiev, M R Bachoo, D A Okhobotov

“…Pathomorphological changes in the testes of the animal of different age groups with experimentally modeled cryptorchism are investigated. All animals were…”
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METABOLIC PATHWAYS by Locasale, J. W., Melman, T., Song, S. S., Yang, X., Swanson, K. D., Cantley, L. C., Asara, J. M., Wong, E. T., Adams, S., Braidy, N., Teo, C., Guillemin, G., Philippe, M., Carole, C., David, T., Eric, G., Isabelle, N.-M., de Paula Andre, M., Marylin, B., Olivier, C., L'Houcine, O., Dominique, F.-B., Leukel, P., Seliger, C., Vollmann, A., Jachnik, B., Bogdahn, U., Hau, P., Liu, X., Kumar, V. S., McPherson, C. M., Chow, L., Kendler, A., Dasgupta, B., Piya, S., White, E., Klein, S., Jiang, H., Lang, F., Alfred Yung, W. K., Gomez-Manzano, C., Fueyo, J., Vartanian, A., Guha, A., Fenton, K. E., Abdelwahab, M., Scheck, A. C., Guo, D., Reinitz, F., Youssef, M., Hong, C., Nathanson, D., Akhavan, D., Kuga, D., Amzajerdi, A. N., Soto, H., Zhu, S., Babic, I., Iwanami, A., Tanaka, K., Gini, B., DeJesus, J., Lisiero, D. D., Huang, T., Prins, R., Wen, P., Robbins, H. I., Prados, M., DeAngelis, L., Mellinghoff, I., Mehta, M., James, C. D., Chakravarti, A., Cloughesy, T., Tontonoz, P., Mischel, P., Phillips, J., Mukherjee, J., Cowdrey, C., Wiencke, J., Pieper, R. O., Bachoo, R., Marin-Valencia, I., Cho, S., Rakheja, D., Hatanpaa, K., Mashimo, T., Vemireddy, V., Kapur, P., Good, L., Sun, X., Pascual, J., Takahashi, M., Togao, O., Raisanen, J., Maher, E. A., DeBerardinis, R., Malloy, C., Choi, C., Mathews, D.

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CELL BIOLOGY AND SIGNALING by Furnari, F., Fenton, T., Nathanson, D., de Alberquerque, C. P., Kuga, D., Wanami, A., Dang, J., Yang, H., Tanaka, K., Gao, L., Oba-Shinjo, S., Uno, M., Inda, M.-d.-M., Bachoo, R., James, C. D., DePinho, R., Vandenberg, S., Zhou, H., Marie, S., Mischel, P., Cavenee, W., Szerlip, N., Pedraza, A., Huse, J., Mikkelsen, T., Brennan, C., Castellani, R. J., Ivanova, S., Gerzanich, V. V., Simard, J. M., Ito, M., See, W., Mukherjee, J., Ohba, S., Tan, I.-L., Pieper, R. O., Lukiw, W. J., Culicchia, F., Pogue, A., Bhattacharjee, S., Zhao, Y., Proescholdt, M. A., Merrill, M., Storr, E. M., Lohmeier, A., Brawanski, A., Abraham, S., Jensen, R., Khatua, S., Gopal, U., Du, J., He, F., Golub, T., Isaacs, J. S., Dietrich, J., Kalogirou-Valtis, Y., Ly, I., Scadden, D., Proschel, C., Mayer-Proschel, M., Rempel, S. A., Schultz, C. R., Golembieski, W., Brodie, C., Mathew, L. K., Skuli, N., Mucaj, V., Imtiyaz, H. Z., Venneti, S., Lal, P., Zhang, Z., Davuluri, R. V., Koch, C., Evans, S., Simon, M. C., Ranganathan, P., Clark, P., Salamat, S., Kuo, J. S., Kalejta, R. F., Bhattacharjee, B., Renzette, N., Moser, R. P., Kowalik, T. F., McFarland, B. C., Ma, J.-Y., Langford, C. P., Gillespie, G. Y., Yu, H., Zheng, Y., Nozell, S. E., Huszar, D., Benveniste, E. N., Lawrence, J. E., Cook, N. J., Rovin, R. A., Winn, R. J., Godlewski, J. A., Ogawa, D., Bronisz, A.

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Microsurgical C-2 ganglionectomy for chronic intractable occipital pain by LOZANO, A. M, VANDERLINDEN, G, BACHOO, R, ROTHBART, P

“…The authors evaluated the effectiveness of microsurgical C-2 ganglionectomy in 39 patients with medically refractory chronic occipital pain. In this procedure…”
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Gubernatorial decision -making: A case study of gubernatorial influence on the contemporary development of Connecticut public higher education from 1980–2001 by Bachoo, Richard R

“…Past gubernatorial decisions, some made over two decades ago, have played an important role in the present rebirth and national recognition of public higher…”
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Gubernatorial decision -making: A case study of gubernatorial influence on the contemporary development of Connecticut public higher education from 1980--2001 by Bachoo, Richard R

“…Past gubernatorial decisions, some made over two decades ago, have played an important role in the present rebirth and national recognition of public higher…”
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