Search Results - "Bachhuber, Franziska"

Diagnostic biomarkers in tear fluid: from sampling to preanalytical processing by Bachhuber, Franziska, Huss, André, Senel, Makbule, Tumani, Hayrettin

“…Tear fluid is receiving growing attention as a source for novel diagnostic biomarkers. Multiple techniques are available for its collection and impact the…”
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The cerebrospinal fluid and barriers - anatomic and physiologic considerations by Tumani, Hayrettin, Huss, André, Bachhuber, Franziska

“…The cerebrospinal fluid (CSF) space consists of the intracerebral ventricles, subarachnoid spaces of the spine and brain (e.g., cisterns and sulci), and the…”
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CSF Free Light Chains as a Marker of Intrathecal Immunoglobulin Synthesis in Multiple Sclerosis: A Blood-CSF Barrier Related Evaluation in a Large Cohort by Senel, Makbule, Mojib-Yezdani, Fatemeh, Braisch, Ulrike, Bachhuber, Franziska, Lewerenz, Jan, Ludolph, Albert C, Otto, Markus, Tumani, Hayrettin

“…The importance of immunoglobulin G (IgG) oligoclonal bands (OCB) in the diagnosis of multiple sclerosis (MS) was reaffirmed again in the recently revised MS…”
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Multiple Sclerosis and Clostridium perfringens Epsilon Toxin: Is There a Relationship? by Huss, André, Bachhuber, Franziska, Feraudet-Tarisse, Cécile, Hiergeist, Andreas, Tumani, Hayrettin

“…Recent research has suggested a link between multiple sclerosis and the gut microbiota. This prospective pilot study aimed to investigate the composition of…”
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Proteomic analysis of SRF associated transcription complexes identified TFII-I as modulator of SRF function in neurons by Meyer zu Reckendorf, Christopher, Anastasiadou, Sofia, Bachhuber, Franziska, Franz-Wachtel, Mirita, Macek, Boris, Knöll, Bernd

“…•We provide a first quantitative proteome study of SRF transcription complexes.•TFII-I was identified as potentially new neuronal SRF cofactor.•TFII-I…”
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A one-year longitudinal evaluation of cerebrospinal fluid and blood neurochemical markers in a patient with cryptococcal meningitis complicated by ischemic stroke by Abu-Rumeileh, Samir, Garibashvili, Tamara, Hagemann, Jürgen Benjamin, Still, Veronika, Bachhuber, Franziska, Otto, Markus, Tumani, Hayrettin, Senel, Makbule

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Primary lateral sclerosis: application and validation of the 2020 consensus diagnostic criteria in an expert opinion-based PLS cohort by Witzel, Simon, Micca, Veronika, Müller, Hans P, Huss, André, Bachhuber, Franziska, Dorst, Johannes, Lulé, Dorothée E, Tumani, Hayrettin, Kassubek, Jan, Ludolph, Albert C

“…BackgroundValidation of the 2020 consensus criteria for primary lateral sclerosis (PLS) is essential for their use in clinical practice and future…”
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Association of cerebrospinal fluid kappa free light chains with the intrathecal polyspecific antiviral immune response in multiple sclerosis by Huss, André, Mojib-Yezdani, Fatemeh, Bachhuber, Franziska, Fangerau, Tanja, Lewerenz, Jan, Otto, Markus, Tumani, Hayrettin, Senel, Makbule

“…The polyspecific B-lymphocyte response to neurotropic viruses such as measles (M), rubella (R) and varicella zoster (Z), known as MRZ reaction, is to-date the…”
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Population-Based Evidence for the Use of Serum Neurofilaments as Individual Diagnostic and Prognostic Biomarkers in Amyotrophic Lateral Sclerosis by Witzel, Simon, Huss, André, Nagel, Gabriele, Rosenbohm, Angela, Rothenbacher, Dietrich, Peter, Raphael S, Bäzner, Hansjörg, Börtlein, Axel, Dempewolf, Silke, Schabet, Martin, Hecht, Martin, Kohler, Andreas, Opherk, Christian, Naegele, Andrea, Sommer, Norbert, Lindner, Alfred, Alexudis, Christoforos, Bachhuber, Franziska, Halbgebauer, Steffen, Brenner, David, Ruf, Wolfgang, Weiland, Ulrike, Mayer, Benjamin, Schuster, Joachim, Dorst, Johannes, Tumani, Hayrettin, Ludolph, Albert C

“…Neurofilament light chains (NfL) and phosphorylated neurofilament heavy chains (pNfH), established as diagnostic and prognostic biomarkers in hospital-based…”
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Clinical characterization of common pathogenic variants of SOD1-ALS in Germany by Wiesenfarth, Maximilian, Forouhideh-Wiesenfarth, Yalda, Elmas, Zeynep, Parlak, Özlem, Weiland, Ulrike, Herrmann, Christine, Schuster, Joachim, Freischmidt, Axel, Müller, Kathrin, Siebert, Reiner, Günther, Kornelia, Fröhlich, Elke, Knehr, Antje, Simak, Tatiana, Bachhuber, Franziska, Regensburger, Martin, Petri, Susanne, Klopstock, Thomas, Reilich, Peter, Schöberl, Florian, Schumann, Peggy, Körtvélyessy, Peter, Meyer, Thomas, Ruf, Wolfgang P., Witzel, Simon, Tumani, Hayrettin, Brenner, David, Dorst, Johannes, Ludolph, Albert C.

“…Pathogenic variants in the Cu/Zn superoxide dismutase ( SOD1 ) gene can be detected in approximately 2% of sporadic and 11% of familial amyotrophic lateral…”
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Serum biomarker levels predict disability progression in patients with primary progressive multiple sclerosis by Fissolo, Nicolás, Benkert, Pascal, Sastre-Garriga, Jaume, Mongay-Ochoa, Neus, Vilaseca-Jolonch, Andreu, Llufriu, Sara, Blanco, Yolanda, Hegen, Harald, Berek, Klaus, Perez-Miralles, Francisco, Rejdak, Konrad, Villar, Luisa M, Monreal, Enric, Alvarez-Lafuente, Roberto, Soylu, Onder K, Abdelhak, Ahmed, Bachhuber, Franziska, Tumani, Hayrettin, Martínez-Yélamos, Sergio, Sánchez-López, Antonio J, García-Merino, Antonio, Gutiérrez, Lucía, Castillo-Trivino, Tamara, Lycke, Jan, Rosenstein, Igal, Furlan, Roberto, Filippi, Massimo, Téllez, Nieves, Ramió-Torrentà, Lluís, Lünemann, Jan D, Wiendl, Heinz, Eichau, Sara, Khalil, Michael, Kuhle, Jens, Montalban, Xavier, Comabella, Manuel

“…BackgroundWe aimed to investigate the potential of serum biomarker levels to predict disability progression in a multicentric real-world cohort of patients…”
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Effects of tofersen treatment in patients with SOD1-ALS in a “real-world” setting – a 12-month multicenter cohort study from the German early access program by Wiesenfarth, Maximilian, Dorst, Johannes, Brenner, David, Elmas, Zeynep, Parlak, Özlem, Uzelac, Zeljko, Kandler, Katharina, Mayer, Kristina, Weiland, Ulrike, Herrmann, Christine, Schuster, Joachim, Freischmidt, Axel, Müller, Kathrin, Siebert, Reiner, Bachhuber, Franziska, Simak, Tatiana, Günther, Kornelia, Fröhlich, Elke, Knehr, Antje, Regensburger, Martin, German, Alexander, Petri, Susanne, Grosskreutz, Julian, Klopstock, Thomas, Reilich, Peter, Schöberl, Florian, Hagenacker, Tim, Weyen, Ute, Günther, René, Vidovic, Maximilian, Jentsch, Martin, Haarmeier, Thomas, Weydt, Patrick, Valkadinov, Ivan, Hesebeck-Brinckmann, Jasper, Conrad, Julian, Weishaupt, Jochen Hans, Schumann, Peggy, Körtvélyessy, Peter, Meyer, Thomas, Ruf, Wolfgang Philipp, Witzel, Simon, Senel, Makbule, Tumani, Hayrettin, Ludolph, Albert Christian

“…In April 2023, the antisense oligonucleotide tofersen was approved by the U.S. Food and Drug Administration (FDA) for treatment of SOD1-amyotrophic lateral…”
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Drug-induced liver injury associated with the biosimilar glatiramer acetate (Clift®) by Michels, Sebastian, Zizer, Eugen, Barth, Thomas FE, Wassner, Anette, Fangerau, Tanja, Taranu, Daniela, Bachhuber, Franziska, Tumani, Hayrettin, Senel, Makbule

“…•Glatiramer acetate is a well-known drug in the long-term treatment of MS.•After the administration of Clift, an increase in liver enzymes was…”
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Association of Complement Factors With Disability Progression in Primary Progressive Multiple Sclerosis by Lunemann, Jan D, Hegen, Harald, Villar, Luisa María, Rejdak, Konrad, Sao-Aviles, Augusto, Carbonell-Mirabent, Pere, Sastre-Garriga, Jaume, Mongay-Ochoa, Neus, Berek, Klaus, Martínez-Yélamos, Sergio, Pérez-Miralles, Francisco, Abdelhak, Ahmed, Bachhuber, Franziska, Tumani, Hayrettin, Lycke, Jan N, Rosenstein, Igal, Alvarez-Lafuente, Roberto, Castillo-Trivino, Tamara, Otaegui, David, Llufriu, Sara, Blanco, Yolanda, Sánchez López, Antonio J, Garcia Merino, Juan Antonio, Fissolo, Nicolas, Gutierrez, Lucia, Villacieros-Álvarez, Javier, Monreal, Enric, Valls-Carbó, Adrián, Wiendl, Heinz, Montalban, Xavier, Comabella, Manuel

“…The complement system is known to play a role in multiple sclerosis (MS) pathogenesis. However, its contribution to disease progression remains elusive. The…”
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Effects of tofersen treatment in patients with SOD1-ALS in a “real-world” setting – a 12-month multicenter cohort study from the German early access programResearch in context by Maximilian Wiesenfarth, Johannes Dorst, David Brenner, Zeynep Elmas, Özlem Parlak, Zeljko Uzelac, Katharina Kandler, Kristina Mayer, Ulrike Weiland, Christine Herrmann, Joachim Schuster, Axel Freischmidt, Kathrin Müller, Reiner Siebert, Franziska Bachhuber, Tatiana Simak, Kornelia Günther, Elke Fröhlich, Antje Knehr, Martin Regensburger, Alexander German, Susanne Petri, Julian Grosskreutz, Thomas Klopstock, Peter Reilich, Florian Schöberl, Tim Hagenacker, Ute Weyen, René Günther, Maximilian Vidovic, Martin Jentsch, Thomas Haarmeier, Patrick Weydt, Ivan Valkadinov, Jasper Hesebeck-Brinckmann, Julian Conrad, Jochen Hans Weishaupt, Peggy Schumann, Peter Körtvélyessy, Thomas Meyer, Wolfgang Philipp Ruf, Simon Witzel, Makbule Senel, Hayrettin Tumani, Albert Christian Ludolph

“…Background: In April 2023, the antisense oligonucleotide tofersen was approved by the U.S. Food and Drug Administration (FDA) for treatment of SOD1-amyotrophic…”
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