Search Results - "Bacher, Felix"

Ready access to 7,8-dihydroindolo[2,3- d ][1]benzazepine-6(5 H )-one scaffold and analogues via early-stage Fischer ring-closure reaction by Kuznetcova, Irina, Bacher, Felix, Vegh, Daniel, Chuang, Hsiang-Yu, Arion, Vladimir B

“…Paullone isomers are known as inhibitors of tubulin polymerase and cyclin dependent kinases (Cdks), which are potential targets for cancer chemotherapy. Herein…”
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Effects of Terminal Dimethylation and Metal Coordination of Proline-2-formylpyridine Thiosemicarbazone Hybrids on Lipophilicity, Antiproliferative Activity, and hR2 RNR Inhibition by Bacher, Felix, Dömötör, Orsolya, Kaltenbrunner, Maria, Mojović, Miloš, Popović-Bijelić, Ana, Gräslund, Astrid, Ozarowski, Andrew, Filipovic, Lana, Radulović, Sinisa, Enyedy, Éva A, Arion, Vladimir B

“…The nickel(II), copper(II), and zinc(II) complexes of the proline-thiosemicarbazone hybrids 3-methyl-(S)-pyrrolidine-2-carboxylate-2-formylpyridine…”
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Geographic tracing of cereals from South Tyrol (Italy) and neighboring regions via 87Sr/86Sr isotope analysis by Bacher, Felix, Aguzzoni, Agnese, Chizzali, Samira, Pignotti, Emanuela, Puntscher, Hannes, Zignale, Pietro, Voto, Giulio, Tagliavini, Massimo, Tirler, Werner, Robatscher, Peter

“…•The grain 87Sr/86Sr ratios was highly correlated to that of the soil.•The cereal species did not affect the 87Sr/86Sr ratios of the grain.•The 87Sr/86Sr ratio…”
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Elucidation of Structure–Activity Relationships in Indolobenzazepine-Derived Ligands and Their Copper(II) Complexes: the Role of Key Structural Components and Insight into the Mechanism of Action by Kuznetcova, Irina, Bacher, Felix, Alfadul, Samah Mutasim, Tham, Max Jing Rui, Ang, Wee Han, Babak, Maria V., Rapta, Peter, Arion, Vladimir B.

“…Indolo­[3,2-d]­[1]­benzazepines (paullones), indolo­[3,2-d]­[2]­benzazepines, and indolo­[2,3-d]­[2]­benzazepines (latonduines) are isomeric scaffolds of…”
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Highly Antiproliferative Latonduine and Indolo[2,3‑c]quinoline Derivatives: Complex Formation with Copper(II) Markedly Changes the Kinase Inhibitory Profile by Wittmann, Christopher, Bacher, Felix, Enyedy, Eva A, Dömötör, Orsolya, Spengler, Gabriella, Madejski, Christian, Reynisson, Jóhannes, Arion, Vladimir B

“…A series of latonduine and indoloquinoline derivatives HL1 –HL8 and their copper­(II) complexes (1–8) were synthesized and comprehensively characterized. The…”
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New Water-Soluble Copper(II) Complexes with Morpholine–Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action by Ohui, Kateryna, Afanasenko, Eleonora, Bacher, Felix, Ting, Rachel Lim Xue, Zafar, Ayesha, Blanco-Cabra, Núria, Torrents, Eduard, Dömötör, Orsolya, May, Nóra V, Darvasiova, Denisa, Enyedy, Éva A, Popović-Bijelić, Ana, Reynisson, Jóhannes, Rapta, Peter, Babak, Maria V, Pastorin, Giorgia, Arion, Vladimir B

“…Six morpholine-(iso)­thiosemicarbazone hybrids HL 1 –HL 6 and their Cu­(II) complexes with good-to-moderate solubility and stability in water were synthesized…”
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Inhibition of Microtubule Dynamics in Cancer Cells by Indole-Modified Latonduine Derivatives and Their Metal Complexes by Wittmann, Christopher, Sivchenko, Anastasiia S, Bacher, Felix, Tong, Kelvin K. H, Guru, Navjot, Wilson, Thomas, Gonzales, Junior, Rauch, Hartmut, Kossatz, Susanne, Reiner, Thomas, Babak, Maria V, Arion, Vladimir B

“…Indolo­[2,3-d]­benzazepines (indololatonduines) are rarely discussed in the literature. In this project, we prepared a series of novel indololatonduine…”
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Novel latonduine derived proligands and their copper(ii) complexes show cytotoxicity in the nanomolar range in human colon adenocarcinoma cells and in vitro cancer selectivity by Bacher, Felix, Wittmann, Christopher, Nové, Márta, Spengler, Gabriella, Marć, Małgorzata A, Enyedy, Eva A, Darvasiová, Denisa, Rapta, Peter, Reiner, Thomas, Arion, Vladimir B

“…Four Schiff bases derived from 7-hydrazin-yl-5,8-dihydroindolo[2,3-d][2]benzazepin-(6H)-one and its bromo-substituted analogue (HL1-HL4) and four copper(ii)…”
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Copper(II) Complexes with Highly Water-Soluble l- and d‑Proline–Thiosemicarbazone Conjugates as Potential Inhibitors of Topoisomerase IIα by Bacher, Felix, Enyedy, Éva A, Nagy, Nóra V, Rockenbauer, Antal, Bognár, Gabriella M, Trondl, Robert, Novak, Maria S, Klapproth, Erik, Kiss, Tamás, Arion, Vladimir B

“…Two proline–thiosemicarbazone bioconjugates with excellent aqueous solubility, namely, 3-methyl-(S)-pyrrolidine-2-carboxylate-2-formylpyridine…”
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Strong effect of copper(II) coordination on antiproliferative activity of thiosemicarbazone-piperazine and thiosemicarbazone-morpholine hybrids by Bacher, Felix, Dömötör, Orsolya, Chugunova, Anastasia, Nagy, Nóra V, Filipović, Lana, Radulović, Siniša, Enyedy, Éva A, Arion, Vladimir B

“…In this study, 2-formylpyridine thiosemicarbazones and three different heterocyclic pharmacophores were combined to prepare thiosemicarbazone–piperazine…”
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Ruthenium− and Osmium−Arene Complexes of 2-Substituted Indolo[3,2-c]quinolines: Synthesis, Structure, Spectroscopic Properties, and Antiproliferative Activity by Filak, Lukas K., Mühlgassner, Gerhard, Bacher, Felix, Roller, Alexander, Galanski, Mathea Sophia, Jakupec, Michael A., Keppler, Bernhard K., Arion, Vladimir B.

“…The synthesis of new modified indolo[3,2-c]quinoline ligands L 1 −L 8 with metal-binding sites is reported. By coordination to ruthenium− and osmium−arene…”
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Complex formation reactions of gallium(III) and iron(III/II) with l-proline-thiosemicarbazone hybrids: A comparative study by Bacher, Felix, Dömötör, Orsolya, Enyedy, Éva A., Filipović, Lana, Radulović, Siniša, Smith, Gregory S., Arion, Vladimir B.

“…Two gallium(III) complexes with l-proline-thiosemicarbazone hybrids have been synthesised and comprehensively characterised. Reaction of iron(III) with the…”
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