Search Results - "Bachelor, Michael A"

Pre-validation of an in vitro skin irritation test for medical devices using the reconstructed human tissue model EpiDerm by Kandarova, Helena, Willoughby, Jamin A., De Jong, Wim H., Letasiova, Silvia, Milasova, Tatiana, Bachelor, Michael A., Breyfogle, Bridget, Handa, Yuki, De la Fonteyne, Liset, Coleman, Kelly P.

“…Assessment of dermal irritation is an essential component of the safety evaluation of medical devices. Reconstructed human epidermis (RhE) models have replaced…”
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UVA-mediated activation of signaling pathways involved in skin tumor promotion and progression by Bachelor, Michael A, Bowden, G.Tim

“…Each year more than 1,000,000 cases of non-melanoma skin cancer (NMSC) are diagnosed in the Unites States. Solar radiation has been described as an important…”
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Tbc1d10c is a selective, constitutive suppressor of the CD8 T-cell anti-tumor response by Cohen, Adrienne O., Woo, Seung-Hyun, Zhang, Junya, Cho, Jiyoon, Ruiz, Marlon E., Gong, Jianli, Du, Rong, Yarygina, Olga, Jafri, Danya Z., Bachelor, Michael A., Finlayson, Michael O., Soni, Rajesh K., Hayden, Matthew S., Owens, David M.

“…Cancer immunotherapy approaches target signaling pathways that are highly synonymous between CD4 and CD8 T-cell subsets and, therefore, often stimulate…”
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l -3-Phosphoserine phosphatase (PSPH) regulates cutaneous squamous cell carcinoma proliferation independent of l -serine biosynthesis by Bachelor, Michael A, Lu, Yan, Owens, David M

“…Abstract Background l -3-Phosphoserine phosphatase (PSPH) is a highly conserved and widely expressed member of the haloacid dehalogenase superfamily and the…”
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The Role of JNK and p38 MAPK Activities in UVA-Induced Signaling Pathways Leading to AP-1 Activation and c-Fos Expression by Silvers, Amy L., Bachelor, Michael A., Bowden, G. Timothy

“…To further delineate ultraviolet A (UVA) signaling pathways in the human keratinocyte cell line HaCaT, we examined the potential role of mitogen-activated…”
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mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine by Gupta, Pankaj, Su, Zao-zhong, Lebedeva, Irina V, Sarkar, Devanand, Sauane, Moira, Emdad, Luni, Bachelor, Michael A, Grant, Steven, Curiel, David T, Dent, Paul, Fisher, Paul B

“…"Differentiation therapy" provides a unique and potentially effective, less toxic treatment paradigm for cancer. Moreover, combining "differentiation therapy"…”
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Ultraviolet A-induced modulation of Bcl-XL by p38 MAPK in human keratinocytes: post-transcriptional regulation through the 3'-untranslated region by Bachelor, Michael A, Bowden, G Timothy

“…We examined the effect of inhibiting p38 MAPK on UVA-irradiated HaCaT cells, a spontaneously immortalized human keratinocyte cell line. Recent work from our…”
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Hairless and NFκB Form a Positive Feedback Loop After UVB and TNFα Stimulation by Casta, Alexandre, Kim, Hyunmi, Luke, Courtney T., Bachelor, Michael A., Engelhard, Andrew, Owens, David M., Christiano, Angela M.

“…Hairless (HR) is a nuclear protein with corepressor activity whose exact function in the skin remains to be determined. Mutations in both human and mouse…”
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Inhibition of p38 mitogen-activated protein kinase and phosphatidylinositol 3-kinase decreases UVB-induced activator protein-1 and cyclooxygenase-2 in a SKH-1 hairless mouse model by Bachelor, Michael A, Cooper, Simon J, Sikorski, Ewa T, Bowden, G Timothy

“…Activation of activator protein-1 (AP-1) and increased expression of cyclooxygenase-2 (COX-2) have been clearly shown to play a functional role in UVB-induced…”
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The role of p38 in UVA-induced cyclooxygenase-2 expression in the human keratinocyte cell line, HaCaT by Bachelor, Michael A, Silvers, Amy L, Bowden, Gim T

“…We examined the expression of cycloxygenase-2, the rate-limiting enzyme in the production of prostaglandins, in the UVA-irradiated human keratinocyte cell…”
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Ultraviolet A-induced Modulation of Bcl-XL by p38 MAPK in Human Keratinocytes by Bachelor, Michael A., Bowden, G. Timothy

“…We examined the effect of inhibiting p38 MAPK on UVA-irradiated HaCaT cells, a spontaneously immortalized human keratinocyte cell line. Recent work from our…”
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Determination of nitrate and nitrite in Hanford defense waste by reverse-polarity capillary zone electrophoresis by Okemgbo, Asopuru A, Hill, Herbert H, Metcalf, Steven G, Bachelor, Michael A

“…This paper describes the first application of reverse-polarity capillary zone electrophoresis for rapid and accurate determination of nitrate and nitrite in…”
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Routine production of 2-deoxy-2-[18F]fluoro-D-glucose by direct nucleophilic exchange on a quaternary 4-aminopyridinium resin by Toorongian, S A, Mulholland, G K, Jewett, D M, Bachelor, M A, Kilbourn, M R

“…Resin-supported [18F]fluoride ion has been prepared and applied to a rapid, convenient synthesis of [18F]FDG. "No-carrier-added" [18F]fluoride ion is collected…”
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Hairless and NF[kappa]B Form a Positive Feedback Loop After UVB and TNF Stimulation by Casta, Alexandre, Kim, Hyunmi, Luke, Courtney T, Bachelor, Michael A, Engelhard, Andrew, Owens, David M, Christiano, Angela M

“…Hairless (HR) is a nuclear protein with corepressor activity whose exact function in the skin remains to be determined. Mutations in both human and mouse…”
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Ultraviolet A-induced Modulation of Bcl-X sub(L) by p38 MAPK in Human Keratinocytes: Post-Transcriptional Regulation Through The 3'-Untranslated Region by Bachelor, Michael A, Bowden, GTimothy

“…We examined the effect of inhibiting p38 MAPK on UVA-irradiated HaCaT cells, a spontaneously immortalized human keratinocyte cell line. Recent work from our…”
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The Role of JNK and p38 MAPK Activities in UVA-Induced Signaling Pathways Leading to AP-1 Activation and c-Fos Expression1 by Silvers, Amy L, Bachelor, Michael A, Bowden, G Timothy

“…To further delineate ultraviolet A (UVA) signaling pathways in the human keratinocyte cell line HaCaT, we examined the potential role of mitogen-activated…”
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Inhibition of p38 Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase Decreases UVB-Induced Activator Protein-1 and Cyclooxygenase-2 in a SKH-1 Hairless Mouse Model11NIH grants CA27502 and CA23074, Cancer Research Foundation of America Fellowship (S.J. Cooper), Achievement Rewards for College Scientists Foundation (M.A. Bachelor), and NIH CA23074 (through the support of Drs. Mash and Tadikamalla and the Synthetic Chemistry Shared Service).Note: M.A. Bachelor and S.J. Cooper contri by Michael A. Bachelor, Simon J. Cooper, Ewa T. Sikorski, G. Timothy Bowden

“…Activation of activator protein-1 (AP-1) and increased expression of cyclooxygenase-2 (COX-2) have been clearly shown to play a functional role in UVB-induced…”
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Identification of molecular targets for the chemoprevention of non-melanoma skin cancer by Bachelor, Michael A

“…The ultraviolet (UV) component of sunlight has been identified as a major etiological factor in the development of non-melanoma skin cancer (NMSC)…”
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Extraction of [18F]fluoride from [18O]water by a fast fibrous anion exchange resin by Jewett, D M, Toorongian, S A, Bachelor, M A, Kilbourn, M R

“…[18F]Fluoride for nucleophilic radiofluorination was recovered from target water by trapping on a fibrous anion exchange resin in the hydroxide form and…”
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