Search Results - "Bach, Dominik R"
-
1
Measuring learning in human classical threat conditioning: Translational, cognitive and methodological considerations
Published in Neuroscience and biobehavioral reviews (01-07-2020)“…•At least 10 different measures of human threat conditioning exist in the literature.•Measures are highly variable in translational, cognitive and…”
Get full text
Journal Article -
2
Heuristic and optimal policy computations in the human brain during sequential decision-making
Published in Nature communications (23-01-2018)“…Optimal decisions across extended time horizons require value calculations over multiple probabilistic future states. Humans may circumvent such complex…”
Get full text
Journal Article -
3
Measuring human context fear conditioning and retention after consolidation
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-07-2023)“…Fear conditioning is a laboratory paradigm commonly used to investigate aversive learning and memory. In context fear conditioning, a configuration of…”
Get full text
Journal Article -
4
Human Hippocampus Arbitrates Approach-Avoidance Conflict
Published in Current biology (03-03-2014)“…Animal models of human anxiety often invoke a conflict between approach and avoidance [1, 2]. In these, a key behavioral assay comprises passive avoidance of…”
Get full text
Journal Article -
5
Human Pavlovian fear conditioning conforms to probabilistic learning
Published in PLoS computational biology (31-08-2018)“…Learning to predict threat from environmental cues is a fundamental skill in changing environments. This aversive learning process is exemplified by Pavlovian…”
Get full text
Journal Article -
6
Anxiety-Like Behavioural Inhibition Is Normative under Environmental Threat-Reward Correlations
Published in PLoS computational biology (01-12-2015)“…Behavioural inhibition is a key anxiety-like behaviour in rodents and humans, distinct from avoidance of danger, and reduced by anxiolytic drugs. In some…”
Get full text
Journal Article -
7
Model-based analysis of skin conductance responses: Towards causal models in psychophysiology
Published in Psychophysiology (01-01-2013)“…The empirical investigation of unobservable psychological processes usually rests on operational definitions. As an alternative, we propose the use of explicit…”
Get full text
Journal Article -
8
Computational optimization of associative learning experiments
Published in PLoS computational biology (01-01-2020)“…With computational biology striving to provide more accurate theoretical accounts of biological systems, use of increasingly complex computational models seems…”
Get full text
Journal Article -
9
Dissecting the Function of Hippocampal Oscillations in a Human Anxiety Model
Published in The Journal of neuroscience (19-07-2017)“…Neural oscillations in hippocampus and medial prefrontal cortex (mPFC) are a hallmark of rodent anxiety models that build on conflict between approach and…”
Get full text
Journal Article -
10
How the Opinion of Others Affects Our Valuation of Objects
Published in Current biology (13-07-2010)“…The opinions of others can easily affect how much we value things. We investigated what happens in our brain when we agree with others about the value of an…”
Get full text
Journal Article -
11
Asymmetric representation of aversive prediction errors in Pavlovian threat conditioning
Published in NeuroImage (Orlando, Fla.) (01-11-2022)“…Survival in biological environments requires learning associations between predictive sensory cues and threatening outcomes. Such aversive learning may be…”
Get full text
Journal Article -
12
Acceleration of inferred neural responses to oddball targets in an individual with bilateral amygdala lesion compared to healthy controls
Published in Scientific reports (04-09-2023)“…Detecting unusual auditory stimuli is crucial for discovering potential threat. Locus coeruleus (LC), which coordinates attention, and amygdala, which is…”
Get full text
Journal Article -
13
Action dominates valence in anticipatory representations in the human striatum and dopaminergic midbrain
Published in The Journal of neuroscience (25-05-2011)“…The acquisition of reward and the avoidance of punishment could logically be contingent on either emitting or withholding particular actions. However, the…”
Get full text
Journal Article -
14
Analytic measures for quantification of arousal from spontaneous skin conductance fluctuations
Published in International journal of psychophysiology (01-04-2010)“…Autonomic arousal is often indexed by spontaneous fluctuations in skin conductance. Here, we derive a simple measure of sympathetic arousal, using a…”
Get full text
Journal Article -
15
Representation of probabilistic outcomes during risky decision-making
Published in Nature communications (15-05-2020)“…Goal-directed behaviour requires prospectively retrieving and evaluating multiple possible action outcomes. While a plethora of studies suggested sequential…”
Get full text
Journal Article -
16
Processing of Temporal Unpredictability in Human and Animal Amygdala
Published in The Journal of neuroscience (30-05-2007)“…The amygdala has been studied extensively for its critical role in associative fear conditioning in animals and humans. Noxious stimuli, such as those used for…”
Get full text
Journal Article -
17
Correction: Attenuating human fear memory retention with minocycline: a randomized placebo-controlled trial
Published in Translational psychiatry (14-02-2024)Get full text
Journal Article -
18
Attenuating human fear memory retention with minocycline: a randomized placebo-controlled trial
Published in Translational psychiatry (17-01-2024)“…Pavlovian fear conditioning is widely used as a pre-clinical model to investigate methods for prevention and treatment of anxiety and stress-related disorders…”
Get full text
Journal Article -
19
Deconstructing risk: Separable encoding of variance and skewness in the brain
Published in NeuroImage (Orlando, Fla.) (15-10-2011)“…Risky choice entails a need to appraise all possible outcomes and integrate this information with individual risk preference. Risk is frequently quantified…”
Get full text
Journal Article -
20
The known unknowns: neural representation of second-order uncertainty, and ambiguity
Published in The Journal of neuroscience (30-03-2011)“…Predictions provided by action-outcome probabilities entail a degree of (first-order) uncertainty. However, these probabilities themselves can be imprecise and…”
Get full text
Journal Article