Search Results - "Bach, Alvin C"

The Localization of Phenolic Compounds in Liposomal Bilayers and Their Effects on Surface Characteristics and Colloidal Stability by Malekar, Swapnil A., Sarode, Ashish L., Bach, Alvin C., Worthen, David R.

“…The interactions with and effects of five chemically distinct, bioactive phenolic compounds on the lipid bilayers of model dipalmitoylphosphatidylcholine…”
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Advantages of atmospheric pressure photoionization mass spectrometry in support of drug discovery by Cai, Yanxuan, Kingery, David, McConnell, Oliver, Bach II, Alvin C.

“…The performance of the atmospheric pressure photoionization (APPI) technique was evaluated against five sets of standards and drug‐like compounds and compared…”
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Characterization of Byproducts from Chemical Syntheses of Oligonucleotides Containing 1‑Methyladenine and 3‑Methylcytosine by Tang, Qi, Cai, Ang, Bian, Ke, Chen, Fangyi, Delaney, James C, Adusumalli, Sravani, Bach, Alvin C, Akhlaghi, Fatemeh, Cho, Bongsup P, Li, Deyu

“…Oligonucleotides serve as important tools for biological, chemical, and medical research. The preparation of oligonucleotides through automated solid-phase…”
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Radio Frequency-Activated Nanoliposomes for Controlled Combination Drug Delivery by Malekar, Swapnil A., Sarode, Ashish L., Bach, Alvin C., Bose, Arijit, Bothun, Geoffrey, Worthen, David R.

“…This work was conducted in order to design, characterize, and evaluate stable liposomes containing the hydrophobic drug raloxifene HCl (RAL) and hydrophilic…”
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Suitability of tetrahydofuran as a dopant and the comparison to other existing dopants in dopant-assisted atmospheric pressure photoionization mass spectrometry in support of drug discovery by Cai, Yanxuan, McConnell, Oliver, Bach II, Alvin C.

“…In this paper, we investigated the suitability of tetrahydofuran (THF) as a dopant and compared it against other common dopants for atmospheric pressure…”
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Stereochemical identification of (R)- and (S)-ibuprofen using residual dipolar couplings, NMR, and modeling by Marathias, Vasilios M., Tawa, Gregory J., Goljer, Igor, Bach II, Alvin C.

“…In this work, we describe an NMR‐based method that utilizes an orientation media composed of the chiral polypeptide liquid crystal poly‐γ‐benzyl‐L‐glutamate…”
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Phenolic constituents of Carex vulpinoidea seeds and their tyrosinase inhibitory activities by Niesen, Daniel B, Ma, Hang, Yuan, Tao, Bach, 2nd, Alvin C, Henry, Geneive E, Seeram, Navindra P

“…Two new phenolics, a stilbenoid, vulpinoideol A (1), and a chalcone, vulpinoideol B (2), along with ten known compounds (3-12) were isolated from Carex…”
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Studying Rat Brain Neurochemistry Using Nanoprobe NMR Spectroscopy:  a Metabonomics Approach by Khandelwal, Purnima, Beyer, Chad E, Lin, Qian, Schechter, Lee E, Bach, Alvin C

“…In the present experiments, in vivo microdialysis techniques together with nanoprobe NMR spectroscopy were used to evaluate the neurochemical environment of…”
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The Synthesis and Biological Evaluation of Quinolyl-piperazinyl Piperidines as Potent Serotonin 5-HT1A Antagonists by Childers, Wayne E, Havran, Lisa M, Asselin, Magda, Bicksler, James J, Chong, Dan C, Grosu, George T, Shen, Zhongqi, Abou-Gharbia, Magid, A, Bach, Alvin C, Harrison, Boyd L, Kagan, Natasha, Kleintop, Teresa, Magolda, Ronald, Marathias, Vasilios, Robichaud, Albert J, Sabb, Annmarie L, Zhang, Mei-Yi, Andree, Terrance H, Aschmies, Susan H, Beyer, Chad, Comery, Thomas A, Day, Mark, Grauer, Steven M, Hughes, Zoe A, Rosenzweig-Lipson, Sharon, Platt, Brian, Pulicicchio, Claudine, Smith, Deborah E, Sukoff-Rizzo, Stacy J, Sullivan, Kelly M, Adedoyin, Adedayo, Huselton, Christine, Hirst, Warren D

“…As part of an effort to identify 5-HT1A antagonists that did not possess typical arylalkylamine or keto/amido-alkyl aryl piperazine scaffolds, prototype…”
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Nanoprobe NMR spectroscopy and in vivo microdialysis: new analytical methods to study brain neurochemistry by Khandelwal, Purnima, Beyer, Chad E., Lin, Qian, McGonigle, Paul, Schechter, Lee E., Bach, Alvin C.

“…Nuclear magnetic resonance (NMR) spectroscopy was used to study the chemical composition of cerebrospinal fluid (CSF) microdialysate from the rat brain. In…”
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Structural Studies of a Family of High Affinity Ligands for GPIIb/IIIa by Bach, Alvin C, Eyermann, Charles J, Gross, John D, Bower, Michael J, Harlow, Richard L, Weber, Patrica C, DeGrado, William F

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Mechanism study of N-dephenylation mediated through a N-para-hydroxy metabolite by Wang, Jianyao, DeMaio, William, Chandrasekaran, Appavu, Shen, Li, Bach, 2nd, Alvin C, Scatina, JoAnn, Talaat, Rasmy

“…A P450 catalyzed N-para-hydroxy metabolite was suggested to be a prerequisite for N-dephenylation occurrence. Although two mechanisms have been proposed to…”
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Type II‘ to Type I β-Turn Swap Changes Specificity for Integrins by Bach, Alvin C, Espina, J. Robert, Jackson, Sharon A, Stouten, Pieter F. W, Duke, Jodie L, Mousa, Shaker A, DeGrado, William F

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Simultaneous determination of 1H-1H and 1H-13C residual dipolar couplings in a chiral liquid crystal solvent using a natural abundance HSQC experiment by Marathias, Vasilios M., Goljer, Igor, Bach II, Alvin C.

“…A high‐resolution, phase‐sensitive, natural abundance F2‐coupled 1H–13C HSQC (F2HSQC) NMR experiment was developed to measure simultaneously both nDHH and 1DCH…”
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Normal-Phase Automated Mass-Directed HPLC Purification of a Pyrrolobenzodiazepine Library with Vasopressin Agonist Activity by Kagan, Michael, Chlenov, Michael, Melnikov, Sergey, McConnell, Oliver, Bach, Alvin C, Carter, Guy, Failli, Amedeo, Caggiano, Thomas J, Shumsky, Jay S, Lubda, Dieter

“…A 23-member library of pyrrolobenzodiazepine derivatives with vasopressin agonist activity was purified on a 100-mg per injection scale using normal-phase (NP)…”
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Two-dimensional NMR studies of the antimicrobial peptide NP-5 by Bach, Alvin C, Selsted, Michael E, Pardi, Arthur

“…Nearly complete proton resonance assignment of the rabbit antimicrobial peptide NP-5 has been made from two-dimensional NMR data taken at a single temperature…”
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Structural consequences of an amino acid deletion in the B1 domain of protein G by O'Neil, Karyn T., Bach II, Alvin C., DeGrado, William F.

“…We describe the NMR structure of a deletion mutant of the B1 IgG‐binding domain from Group G Streptococcus. The deletion occurs within the last β‐strand of the…”
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Dehydrophenylalanine as the i + 2th residue of a .beta. turn: synthesis and conformational analysis of cyclo(Gly-Pro-.DELTA.z-Phe-D-Ala-Pro) and cyclo(Gly-Pro-D-Phe-D-Ala-Pro) by Bach, Alvin C, Gierasch, Lila M

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Determination of proline ring nonplanarity from proton spin-spin coupling constants: applications to two cyclic pentapeptides by Bach, Alvin C, Bothner-By, Aksel A, Gierasch, Lila M

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The Synthesis and Biological Evaluation of Quinolyl-piperazinyl Piperidines as Potent Serotonin 5-HT 1A Antagonists by Childers, Wayne E., Havran, Lisa M., Asselin, Magda, Bicksler, James J., Chong, Dan C., Grosu, George T., Shen, Zhongqi, Abou-Gharbia, Magid, A., Bach, Alvin C., Harrison, Boyd L., Kagan, Natasha, Kleintop, Teresa, Magolda, Ronald, Marathias, Vasilios, Robichaud, Albert J., Sabb, Annmarie L., Zhang, Mei-Yi, Andree, Terrance H., Aschmies, Susan H., Beyer, Chad, Comery, Thomas A., Day, Mark, Grauer, Steven M., Hughes, Zoe A., Rosenzweig-Lipson, Sharon, Platt, Brian, Pulicicchio, Claudine, Smith, Deborah E., Sukoff-Rizzo, Stacy J., Sullivan, Kelly M., Adedoyin, Adedayo, Huselton, Christine, Hirst, Warren D.

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