Search Results - "Bacci, Angela"

Protection of Killer Antiidiotypic Antibodies against Early Invasive Aspergillosis in a Murine Model of Allogeneic T-Cell-Depleted Bone Marrow Transplantation by CENCI, Elio, MENCACCI, Antonella, ROMANI, Luigina, SPRECA, Antonio, MONTAGNOLI, Claudia, BACCI, Angela, PERRUCCIO, Katia, VELARDI, Andrea, MAGLIANI, Walter, CONTI, Stefania, POLONELLI, Luciano

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Interleukin 18 Restores Defective Th1 Immunity to Candida albicans in Caspase 1-Deficient Mice by MENCACCI, A, BACCI, A, CENCI, E, MONTAGNOLI, C, FIORUCCI, S, CASAGRANDE, A, FLAVELL, R. A, BISTONI, F, ROMANI, L

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The interaction of fungi with dendritic cells: implications for Th immunity and vaccination by Claudia, Montagnoli, Bacci, Angela, Silvia, Bozza, Gaziano, Roberta, Spreca, Antonio, Romani, Luigina

“…Human beings are continuously exposed to fungi, yet they rarely get fungal diseases. The delicate balance between the host and these otherwise harmless…”
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Dendritic Cells Discriminate between Yeasts and Hyphae of the Fungus Candida albicans by d'Ostiani, Cristiana Fè, Del Sero, Giuseppe, Bacci, Angela, Montagnoli, Claudia, Spreca, Antonio, Mencacci, Antonella, Ricciardi-Castagnoli, Paola, Romani, Luigina

“…The fungus Candida albicans behaves as a commensal as well as a true pathogen of areas highly enriched in dendritic cells, such as skin and mucosal surfaces…”
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Dendritic Cells Transport Conidia and Hyphae of Aspergillus fumigatus from the Airways to the Draining Lymph Nodes and Initiate Disparate Th Responses to the Fungus by Bozza, Silvia, Gaziano, Roberta, Spreca, Antonio, Bacci, Angela, Montagnoli, Claudia, di Francesco, Paolo, Romani, Luigina

“…Aspergilli are respiratory pathogens and pulmonary infections are usually acquired through the inhalation of conidia, able to reach small airways and the…”
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B7/CD28-Dependent CD4+CD25+ Regulatory T Cells Are Essential Components of the Memory-Protective Immunity to Candida albicans by Montagnoli, Claudia, Bacci, Angela, Bozza, Silvia, Gaziano, Roberta, Mosci, Paolo, Sharpe, Arlene H, Romani, Luigina

“…Protective immunity to the fungus Candida albicans is mediated by Ag-specific Th1 cells. Paradoxically, some Th2 cytokines are required for the maintenance of…”
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Dendritic cells discriminate between yeasts and hyphae of the fungus Candida albicans. Implications for initiation of T helper cell immunity in vitro and in vivo by d'Ostiani, C F, Del Sero, G, Bacci, A, Montagnoli, C, Spreca, A, Mencacci, A, Ricciardi-Castagnoli, P, Romani, L

“…The fungus Candida albicans behaves as a commensal as well as a true pathogen of areas highly enriched in dendritic cells, such as skin and mucosal surfaces…”
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T Cell Vaccination in Mice with Invasive Pulmonary Aspergillosis by Cenci, Elio, Mencacci, Antonella, Bacci, Angela, Bistoni, Francesco, Kurup, Viswanath P, Romani, Luigina

“…Aspergillus fumigatus, an opportunistic fungal pathogen, is responsible for multiple airway diseases of an allergic and a nonallergic nature. In a murine model…”
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Vaccination of mice against invasive aspergillosis with recombinant Aspergillus proteins and CpG oligodeoxynucleotides as adjuvants by Bozza, Silvia, Gaziano, Roberta, Lipford, Grayson B., Montagnoli, Claudia, Bacci, Angela, Di Francesco, Paolo, Kurup, Viswanath P., Wagner, Hermann, Romani, Luigina

“…In a murine model of invasive pulmonary aspergillosis, dendritic cells (DCs) pulsed with Aspergillus antigens induced the activation of CD4 + Th1 cells capable…”
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CD80+Gr-1+ Myeloid Cells Inhibit Development of Antifungal Th1 Immunity in Mice with Candidiasis by Mencacci, Antonella, Montagnoli, Claudia, Bacci, Angela, Cenci, Elio, Pitzurra, Lucia, Spreca, Antonio, Kopf, Manfred, Sharpe, Arlene H, Romani, Luigina

“…To find out whether polymorphonuclear neutrophils (PMN), abundantly recruited in disseminated Candida albicans infection, could directly affect the activation…”
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Dendritic Cells Pulsed with Fungal RNA Induce Protective Immunity to Candida albicans in Hematopoietic Transplantation by Bacci, Angela, Montagnoli, Claudia, Perruccio, Katia, Bozza, Silvia, Gaziano, Roberta, Pitzurra, Lucia, Velardi, Andrea, d'Ostiani, Cristiana Fe', Cutler, Jim E, Romani, Luigina

“…Immature myeloid dendritic cells (DC) phagocytose yeasts and hyphae of the fungus Candida albicans and induce different Th cell responses to the fungus…”
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Interleukin-4 Causes Susceptibility to Invasive Pulmonary Aspergillosis through Suppression of Protective Type I Responses by Cenci, Elio, Mencacci, Antonella, Del Sero, Giuseppe, Bacci, Angela, Montagnoli, Claudia, Fè d'Ostiani, Cristiana, Mosci, Paolo, Bachmann, Martin, Bistoni, Francesco, Kopf, Manfred, Romani, Luigina

“…Aspergillus fumigatus, an opportunistic fungal pathogen, causes multiple allergic and non-allergic airway diseases. Invasive pulmonary aspergillosis (IPA) is a…”
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Cytokine- and T Helper-Dependent Lung Mucosal Immunity in Mice with Invasive Pulmonary Aspergillosis by Cenci, Elio, Mencacci, Antonella, Fè d'Ostiani, Cristiana, Del Sero, Giuseppe, Mosci, Paolo, Montagnoli, Claudia, Bacci, Angela, Romani, Luigina

“…The role of cytokine- and T helper (Th)-dependent lung mucosal antifungal immunity in murine invasive pulmonary aspergillosis (IPA) was investigated. Intact or…”
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A role for antibodies in the generation of memory antifungal immunity by Montagnoli, Claudia, Bozza, Silvia, Bacci, Angela, Gaziano, Roberta, Mosci, Paolo, Morschhäuser, Joachim, Pitzurra, Lucia, Kopf, Manfred, Cutler, Jim, Romani, Luigina

“…Protective immunity to Candida albicans and Aspergillus fumigatus is mediated by antigen‐specific Th1 cells. To define the role of B cells and antibodies in…”
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Endogenous interleukin 4 is required for development of protective CD4+ T helper type 1 cell responses to Candida albicans by Mencacci, A, Del Sero, G, Cenci, E, d'Ostiani, C F, Bacci, A, Montagnoli, C, Kopf, M, Romani, L

“…Interleukin (IL)-4-deficient mice were used to assess susceptibility to systemic or gastrointestinal Candida albicans infections, as well as parameters of…”
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Immunogenicity and protective effect of recombinant enolase of Candida albicans in a murine model of systemic candidiasis by Montagnoli, Claudia, Sandini, Silvia, Bacci, Angela, Romani, Luigina, Valle, Roberto La

“…Enolase, a 46-kDa glycolytic enzyme, is an immunodominant antigen of the opportunistic pathogen Candida albicans. A recombinant 6×His-tagged enolase was…”
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Defective antifungal T-helper 1 (TH1) immunity in a murine model of allogeneic T-cell–depleted bone marrow transplantation and its restoration by treatment with TH2 cytokine antagonists by Mencacci, Antonella, Perruccio, Katia, Bacci, Angela, Cenci, Elio, Benedetti, Roberta, Martelli, Massimo F., Bistoni, Francesco, Coffman, Robert, Velardi, Andrea, Romani, Luigina

“…Patients undergoing full haplotype-mismatched hematopoietic transplantations may experience severe intractable invasive fungal infections. To verify whether an…”
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Antifungal type 1 responses are upregulated in IL-10-deficient mice by Del Sero, Giuseppe, Mencacci, Antonella, Cenci, Elio, Fè d'Ostiani, Cristiana, Montagnoli, Claudia, Bacci, Angela, Mosci, Paolo, Kopf, Manfred, Romani, Luigina

“…C57BL/6 mice are highly resistant to infections caused by Candida albicans and Aspergillus fumigatus. To elucidate the role of IL-10 produced by C57BL/6 mice…”
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Host Immune Reactivity Determines the Efficacy of Combination Immunotherapy and Antifungal Chemotherapy in Candidiasis by Mencacci, Antonella, Cenci, Elio, Bacci, Angela, Bistoni, Francesco, Romani, Luigina

“…In immunocompetent mice with candidiasis, successful therapy with amphotericin B and fluconazole relies on the induction of protective, T helper (Th) type 1…”
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IFN-gamma is required for IL-12 responsiveness in mice with Candida albicans infection by Cenci, E, Mencacci, A, Del Sero, G, d'Ostiani, C F, Mosci, P, Bacci, A, Montagnoli, C, Kopf, M, Romani, L

“…To elucidate the role of IFN-gamma in antifungal CD4+ Th-dependent immunity, 129/Sv/Ev mice deficient for IFN-gamma receptor (IFN-gammaR(-/-)) were assessed…”
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