Search Results - "Baccega, Tania"
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Nicotinic acid timed to feeding reverses tissue lipid accumulation and improves glucose control in obese Zucker rats[S]
Published in Journal of lipid research (01-01-2017)“…Nicotinic acid (NiAc) is a potent inhibitor of lipolysis, acutely reducing plasma free fatty acid (FFA) concentrations. However, a major FFA rebound is seen…”
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Galectin-3 in Prostate Cancer Stem-Like Cells Is Immunosuppressive and Drives Early Metastasis
Published in Frontiers in immunology (10-09-2020)“…Galectin-3 (Gal-3) is an extracellular matrix glycan-binding protein with several immunosuppressive and pro-tumor functions. The role of Galectin-3 in cancer…”
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3
Differential induction of Ly6G and Ly6C positive myeloid derived suppressor cells in chronic kidney and liver inflammation and fibrosis
Published in PloS one (04-03-2015)“…CD11b+Gr1+ myeloid derived suppressor cells (MDSC) are known to be very potent suppressors of T cell immunity and can be further stratified into granulocytic…”
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4
Dendritic cells steering antigen and leukocyte traffic in lymph nodes
Published in FEBS letters (12-07-2024)“…Dendritic cells (DCs) play a central role in initiating and shaping the adaptive immune response, thanks to their ability to uptake antigens and present them…”
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5
In vivo CRISPR editing with no detectable genome-wide off-target mutations
Published in Nature (London) (01-09-2018)“…CRISPR–Cas genome-editing nucleases hold substantial promise for developing human therapeutic applications 1 – 6 but identifying unwanted off-target mutations…”
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6
Engineering of immune checkpoints B7-H3 and CD155 enhances immune compatibility of MHC-I−/− iPSCs for β cell replacement
Published in Cell reports (Cambridge) (27-09-2022)“…Induced pluripotent stem cells (iPSCs) represent a source from which β cells can be derived for diabetes replacement therapy. However, their application may be…”
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7
In vivo CRISPR editing with no detectable genomewide off-target mutations
Published in Nature (London) (20-09-2018)“…CRISPR-Cas genome-editing nucleases hold substantial promise for developing human therapeutic applications but identifying unwanted off-target mutations is…”
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8
Differential Induction of Ly6G and Ly6C Positive Myeloid Derived Suppressor Cells in Chronic Kidney and Liver Inflammation and Fibrosis: e0119662
Published in PloS one (01-03-2015)“…CD11b+Gr1+ myeloid derived suppressor cells (MDSC) are known to be very potent suppressors of T cell immunity and can be further stratified into granulocytic…”
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