Search Results - "Baca, Y."

Distinct genomic landscapes of gastroesophageal adenocarcinoma depending on PD-L1 expression identify mutations in RAS–MAPK pathway and TP53 as potential predictors of immunotherapy efficacy by Wang, J.Y., Xiu, J., Baca, Y., Arai, H., Battaglin, F., Kawanishi, N., Soni, S., Zhang, W., Millstein, J., Shields, A.F., Grothey, A., Weinberg, B.A., Marshall, J.L., Lou, E., Khushman, M., Sohal, D.P.S., Hall, M.J., Oberley, M., Spetzler, D., Shen, L., Korn, W.M., Lenz, H.J.

“…The impact of molecular alterations on programmed death-ligand 1 (PD-L1) combined positive score (CPS) is not well studied in gastroesophageal adenocarcinomas…”
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Exploring the differences in the tumor microenvironment and immuno-oncologic targets in pancreatic ductal adenocarcinomas (PDAC) according to KRAS mutational status by E.B. Faber, Y. Baca, J. Xiu, P. Walker, G. Manji, S. Gholami, A. Saeed, A. Prakash, G.P. Botta, D. Sohal, H.J. Lenz, A.F. Shields, C. Nabhan, W. El-Deiry, A. Seeber, V. Chiu, J. Hwang, E. Lou

“…Background: The majority of pancreatic ductal adenocarcinomas (PDACs) are driven by mutant (mt) KRAS. How mt KRAS and co-driver mutations affect the immune…”
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Assessment of immune biomarkers and establishing a triple negative phenotype in gynecologic cancers by Contos, G., Baca, Y., Xiu, J., Brown, J., Holloway, R., Korn, W.M., Herzog, T.J., Jones, N., Winer, I.

“…Immuno-oncology (IO) has rapidly evolved, with many IO therapies either approved or under investigation for multiple malignancies. Biomarkers exist that can…”
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Hepatitis C Virus Infection After Renal Transplantation by Romero, E, Galindo, P, Bravo, J.A, Osorio, J.M, Pérez, A, Baca, Y, Ferreira, C, Asensio, C, Osuna, A

“…Abstract Hepatitis C virus (HCV) infection is the main cause of liver disease after renal transplantation. Most patients have seroconverted on dialysis to…”
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Quiste hidatídico intracardíaco en una niña: reporte de caso by Huerta-Obando, Anderson V, Olivera-Baca, Erick Y, Silva-Díaz, Jaime, Salazar-Díaz, Abel

“…La equinococosis es una infección parasitaria provocada por Echinococcus granulosus, que, en su estado quístico, forma al denominado quiste hidatídico…”
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1132P Chemokine expression in uveal melanoma and association with tumor genetics and response to immunotherapy by Nallagangula, A., Baca, Y., Elliott, A., Walker, P., Abdulla, F., Moser, J., Shao, Y., Lutzky, J.

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Molecular profiling of PDAC of the H versus B/T reveals differences in the tumor microenvironment by Abdelrahim, M., Esmail, A., Kasi, A., Esnaola, N.F., Xiu, J., Baca, Y., Weinberg, B.A.

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72P Pan-tumor survey of RET fusions as detected by next-generation RNA sequencing identified RET+ colorectal carcinoma as a unique molecular subset of CRC by Nagasaka, M., Brazel, D., Baca, Y., Xiu, J., Al-Hallak, M.N., Kim, C., Nieva, J.J., Swensen, J.J., Spetzler, D., Korn, W.M., Socinski, M.A., Halmos, B., Ou, S-H.I.

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105P Pan-tumor survey of ROS1 fusions detected by next-generation RNA sequencing by Zhang, S., Nagasaka, M., Baca, Y., Xiu, J., J.J. Nieva, VanderWalde, A., Swensen, J.J., Spetzler, D., Korn, W.M., Liu, S.V., Ou, S-H.I.

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1806P Analysis of germ-line mutations in non-syndromic malignancies with concurrent pathogenic variants in BRCA1, BRCA2, PALB2, ATM, CHEK2, and RAD51C/D by Miller, E.M., Mullins, J., Jain, A., Chaudhry, A., Mi, D., Usman, R., Jones, T., Baca, Y., Xiu, J., Korn, W.M., Cummings, S., Vidal, G.

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1723P CLEC3B mRNA expression levels are linked to distinct genetic backgrounds, transcriptomic signatures and survival in NSCLC by Seeber, A., Baca, Y., Xiu, J., Puri, S., Owonikoko, T.K., Oliver, T., Kerrigan, K., Patel, S., Uprety, D., Mamdani, H., Kulkarni, A., Lopes, G., Halmos, B., Borghaei, H., Akerley, W., Liu, S.V., Korn, W.M., Pircher, A., Wolf, D., Kocher, F.

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Differences in the molecular landscape of uterine cancer between African American and Caucasian patients by Paladugu, R., Baca, Y., Xiu, J., Rocconi, R.P., ElNaggar, A.C., Winer, I., Brown, J., Scalici, J.M., Pierce, J.Y., Finan, M.A., Jones, N.L.

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480P Gene expression of NANOG and NANOGP8 in colorectal cancer by Arai, H., Baca, Y., Xiu, J., Battaglin, F., Hwang, J., Marshall, J.L., Goldberg, R.M., Weinberg, B.A., Sohal, D., Lou, E., Hall, M.J., Wang, J., Kawanishi, N., Jayachandran, P., Soni, S., Zhang, W., Magee, D., Korn, W.M., Lenz, H.J.

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1952P Comprehensive profiling of MDM2 amplified gastrointestinal (GI) cancers by Battaglin, F., Xiu, J., Baca, Y., Shields, A.F., Goldberg, R.M., Puccini, A., Tokunaga, R., Arai, H., Wang, J., Kawanishi, N., Seeber, A., Astaturov, I., Lockhart, A.C., Zhang, W., Marshall, J.L., Korn, W.M., Lenz, H.J.

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1882PD - Comprehensive molecular characterization of brain metastases (BM) from colorectal cancer (CRC) by Battaglin, F., Xiu, J., Baca, Y., Goldberg, R.M., Grothey, A., Shields, A.F., Seeber, A., Salem, M.E., Puccini, A., Tokunaga, R., Naseem, M., Arai, H., Wang, J., Berger, M.D., Zhang, W., Philip, P.A., Marshall, J.L., Korn, W.M., Lenz, H.J.

“…Although rare, the incidence of BM is increasing due to the improvement in metastatic CRC treatment and longer survival. Genomic analyses of small series…”
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WRN mutated colorectal cancer (CRC) is characterized by a distinct molecular and immunological profile by Seeber, A., Puccini, A., Xiu, J., Baca, Y., Spizzo, G., Zimmer, K., Lenz, H.J., Battaglin, F., Goldberg, R.M., Grothey, A., Shields, A.F., Salem, M.E., Marshall, J.L., Korn, W.M., Wolf, D., Kocher, F.

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645PWRN mutated colorectal cancer (CRC) is characterized by a distinct molecular and immunological profile by Seeber, A, Puccini, A, Xiu, J, Baca, Y, Spizzo, G, Zimmer, K, Lenz, H J, Battaglin, F, Goldberg, R M, Grothey, A, Shields, A F, Salem, M E, Marshall, J L, Korn, W M, Wolf, D, Kocher, F

“…Abstract Background Werner syndrome gene (WRN) encodes a DNA helicase with an exonuclease activity that contributes to DNA repair. In cancer, WRN mutations…”
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Comprehensive molecular characterization of brain metastases (BM) from colorectal cancer (CRC) by Battaglin, F., Xiu, J., Baca, Y., Goldberg, R.M., Grothey, A., Shields, A.F., Seeber, A., Salem, M.E., Puccini, A., Tokunaga, R., Naseem, M., Arai, H., Wang, J., Berger, M.D., Zhang, W., Philip, P.A., Marshall, J.L., Korn, W.M., Lenz, H.J.

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645P - WRN mutated colorectal cancer (CRC) is characterized by a distinct molecular and immunological profile by Seeber, A., Puccini, A., Xiu, J., Baca, Y., Spizzo, G., Zimmer, K., Lenz, H.J., Battaglin, F., Goldberg, R.M., Grothey, A., Shields, A.F., Salem, M.E., Marshall, J.L., Korn, W.M., Wolf, D., Kocher, F.

“…Werner syndrome gene (WRN) encodes a DNA helicase with an exonuclease activity that contributes to DNA repair. In cancer, WRN mutations lead to genomic…”
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1882PDComprehensive molecular characterization of brain metastases (BM) from colorectal cancer (CRC) by Battaglin, F, Xiu, J, Baca, Y, Goldberg, R M, Grothey, A, Shields, A F, Seeber, A, Salem, M E, Puccini, A, Tokunaga, R, Naseem, M, Arai, H, Wang, J, Berger, M D, Zhang, W, Philip, P A, Marshall, J L, Korn, W M, Lenz, H J

“…Abstract Background Although rare, the incidence of BM is increasing due to the improvement in metastatic CRC treatment and longer survival. Genomic analyses…”
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