Search Results - "Babu, N. Jagadeesh"

Nitrofurantoin-p-aminobenzoic acid cocrystal: hydration stability and dissolution rate studies by Cherukuvada, Suryanarayan, Babu, N Jagadeesh, Nangia, Ashwini

“…Nitrofurantoin (NF) drug is known to transform to a hydrate form in aqueous medium. The hydration stability and dissolution rate of a few cocrystals of NF were…”
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Crystal Engineering of Stable Temozolomide Cocrystals by Babu, N. Jagadeesh, Sanphui, Palash, Nangia, Ashwini

“…The antitumor prodrug temozolomide (TMZ) decomposes in aqueous medium of pH≥7 but is relatively stable under acidic conditions. Pure TMZ is obtained as a white…”
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Conformational and Synthon Polymorphism in Furosemide (Lasix) by Babu, N. Jagadeesh, Cherukuvada, Suryanarayan, Thakuria, Ranjit, Nangia, Ashwini

“…Two polymorphs of the well-known diuretic drug Lasix, generic name furosemide, are characterized by single crystal X-ray diffraction to give a trimorphic…”
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Sulfonamide−Pyridine-N-oxide Cocrystals by Goud, N. Rajesh, Babu, N. Jagadeesh, Nangia, Ashwini

“…Hydrogen-bond motifs for the supramolecular synthesis of sulfonamide−pyridine-N-oxide complexes were derived from the analysis of cocrystal structures of aryl…”
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Solubility Advantage of Amorphous Drugs and Pharmaceutical Cocrystals by Babu, N. Jagadeesh, Nangia, Ashwini

“…The current phase of drug development is witnessing an oncoming crisis due to the combined effects of increasing R&D costs, decreasing number of new drug…”
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Anti-tubercular agents. Part 8: Synthesis, antibacterial and antitubercular activity of 5-nitrofuran based 1,2,3-triazoles by Kamal, Ahmed, Hussaini, Syed Mohammed Ali, Faazil, Shaikh, Poornachandra, Y., Narender Reddy, G., Kumar, C. Ganesh, Rajput, Vikrant Singh, Rani, Chitra, Sharma, Rashmi, Khan, Inshad Ali, Jagadeesh Babu, N.

“…A series of 5-nitrofuran–triazole conjugates were synthesized and evaluated for their antimicrobial activity against both Gram-positive and Gram-negative…”
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Polymorphs and Polymorphic Cocrystals of Temozolomide by Babu, N. Jagadeesh, Reddy, L. Sreenivas, Aitipamula, Srinivasulu, Nangia, Ashwini

“…Crystal polymorphism in the antitumor drug temozolomide (TMZ), cocrystals of TMZ with 4,4′‐bipyridine‐N,N′‐dioxide (BPNO), and solid‐state stability were…”
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One-Pot Synthesis of 2-Imino-4-(trifluoromethyl)thiazolidin-4-ol Derivatives in a Three-Component Reaction: Application to Structurally Diverse Scaffolds of Biological Interest Through Subsequent Reactions by Dalmal, Tulshiram, Appalanaidu, K., Kosurkar, Umesh B., Jagadeesh Babu, N., Kumbhare, Ravindra M.

“…A highly efficient method for the synthesis of 2‐imino‐4‐(trifluoromethyl)thiazolidin‐4‐ol derivatives has been achieved by the one‐pot, three‐component…”
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Conformation analysis of 1″,4″-Dispirocyclohexane-6,6′-bis(benzothiazoline): Combined IR, Raman, XRD and DFT approach by P.J., Arathi, Gupta, Parth, Babu N., Jagadeesh, C.N., Sundaresan, Venkatnarayan, Ramanathan

“…The subject of the study is the structure and conformation of 1″,4″-Dispiro-cyclohexane-6,6′-bis(benzothiazoline), a dispiro compound that has a cyclohexyl…”
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Multiple Z‘ in Carboxylic Acid−Pyridine Trimer Synthon and Kagomé Lattice in the Structure of 5-Methylpyrazine-2,3-dicarboxylic Acid by Babu, N. Jagadeesh, Nangia, Ashwini

“…We show the requirement of Z‘ ≥ 2 for assembling an acid−pyridine trimer synthon in small, dissymmetric molecules. 5-Methylpyrazine-2,3-dicarboxylic acid (1)…”
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Synthesis of Novel Diverse Methoxybenzenes‐substituted 2H/4H‐chromene Derivatives in the Presence of InBr3 (5 mol%) and their Cytotoxic Activity by K., Ratnakar Reddy, D., Krishna Swaroop, N., Ravikumar, G., Sravanthi Devi, Y., Poornachandra, N., Jagadeesh Babu, C., Ganesh Kumar, Banda, Narsaiah

“…A series of novel 2‐(trifluoromethyl)‐2H/4H‐chromene‐3‐carboxylate isomers 3 and 4 functionalized with diverse methoxybenzenes 2 at position 4 in compound 3…”
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Crystal Structures of Norfloxacin Hydrates by Roy, Saikat, Goud, N. Rajesh, Babu, N. Jagadeesh, Iqbal, Javed, Kruthiventi, Anil K, Nangia, Ashwini

“…Two novel hydrate forms of norfloxacin (NF) were serendipitously obtained during cocrystallization with eugenol. NF 1.25 hydrate and 1.125 hydrate are…”
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Amide−N-Oxide Heterosynthon and Amide Dimer Homosynthon in Cocrystals of Carboxamide Drugs and Pyridine N-Oxides by Babu, N. Jagadeesh, Reddy, L. Sreenivas, Nangia, Ashwini

“…The carboxamide−pyridine N-oxide heterosynthon is sustained by syn(amide)N−H···O-(oxide) hydrogen bond and auxiliary (N-oxide)C−H···O(amide) interaction…”
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l-Proline catalyzed efficient and convenient synthesis of substituted 2H-chromenes by three-component reaction by Chandrasekhara Rao, L., Meshram, H.M., Satish Kumar, N., Nageswara Rao, N., Jagadeesh Babu, N.

“…A convenient and efficient method is described for the synthesis of alkoxy substituted 2H-chromens by l-proline catalyzed reaction of salicylaldehydes with…”
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Carboxamide-pyridine N-oxide heterosynthon for crystal engineering and pharmaceutical cocrystals by Reddy, L Sreenivas, Babu, N Jagadeesh, Nangia, Ashwini

“…The novel carboxamide-pyridine N-oxide synthon, sustained via N-H...O- hydrogen bonding and C-H...O interaction, is shown to assemble isonicotinamide N-oxide…”
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An efficient regioselective reaction of indole with 2H-chromenes for the synthesis of new 4H-chromenes in environmentally benign media by Chandrasekhara Rao, L., Satish Kumar, N., Jagadeesh babu, N., Meshram, H.M.

“…An efficient regioselective, catalyst free, and green protocol has been developed for the synthesis of a novel class of 4H-chromene scaffolds at room…”
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Nonlinear optical studies and structure-activity relationship of chalcone derivatives with in silico insights by Kar, Swayamsiddha, Adithya, K.S., Shankar, Pruthvik, Jagadeesh Babu, N., Srivastava, Sailesh, Nageswara Rao, G.

“…Nine chalcones were prepared via Claisen-Schmidt condensation, and characterized by UV–vis, IR, 1H NMR, 13C NMR and mass spectrometry. One of the…”
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Crystal Structures of N-Aryl-N′-4-Nitrophenyl Ureas: Molecular Conformation and Weak Interactions Direct the Strong Hydrogen Bond Synthon by Reddy, L. Sreenivas, Chandran, Sreekanth K, George, Sumod, Babu, N. Jagadeesh, Nangia, Ashwini

“…Hydrogen bond competition was studied in 21 X-ray crystal structures of N-X-phenyl-N′-p-nitrophenyl urea compounds (X = H, F, Cl, Br, I, CN, C≡CH, CONH2,…”
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An Efficient One‐Shot Metal‐Free Electrophilic Fluorination of 2‐Iminothiazolidine‐4‐one by Appalanaidu, Killari, Dadmal, Tulshiram L., Patil, Suvarna M., Jagadeesh Babu, N., Laxmikanth Rao, J., Kumbhare, Ravindra M.

“…A highly efficient one‐pot method for the synthesis of mono fluorinated thiazolidinone derivatives have been achieved through four component reaction of…”
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Water-Mediated Multicenter Synthon and Aromatic C−H → N Isostructurality by Babu, N. Jagadeesh, Nangia, Ashwini

“…A strong, cooperative O−H···O hydrogen bond network directs isostructurality in pyrazine tetracarboxylic acid, pyridine tetracarboxylic acid, and pyromellitic…”
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