Search Results - "Babu, Jayachandra R."

Alternatives to Biological Skin in Permeation Studies: Current Trends and Possibilities by Neupane, Rabin, Boddu, Sai H S, Renukuntla, Jwala, Babu, R Jayachandra, Tiwari, Amit K

“…The transdermal route of drugs has received increased attention in recent years due to numerous advantages over the oral and injectable routes, such as…”
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Two Decades-Long Journey from Riluzole to Edaravone: Revisiting the Clinical Pharmacokinetics of the Only Two Amyotrophic Lateral Sclerosis Therapeutics by Dash, Ranjeet Prasad, Babu, R. Jayachandra, Srinivas, Nuggehally R.

“…The recent approval of edaravone has provided an intravenous option to treat amyotrophic lateral sclerosis (ALS) in addition to the existing oral agent,…”
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Exploring the Application of Micellar Drug Delivery Systems in Cancer Nanomedicine by Wang, Qi, Atluri, Keerthi, Tiwari, Amit K, Babu, R Jayachandra

“…Various formulations of polymeric micelles, tiny spherical structures made of polymeric materials, are currently being investigated in preclinical and clinical…”
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Lysinated Multiwalled Carbon Nanotubes with Carbohydrate Ligands as an Effective Nanocarrier for Targeted Doxorubicin Delivery to Breast Cancer Cells by Thakur, Chanchal Kiran, Neupane, Rabin, Karthikeyan, Chandrabose, Ashby, Charles R, Babu, R. Jayachandra, Boddu, Sai H. S, Tiwari, Amit K, Moorthy, Narayana Subbiah Hari Narayana

“…Multiwalled carbon nanotubes (MWCNTs) are elongated, hollow cylindrical nanotubes made of sp2 carbon. MWCNTs have attracted significant attention in the area…”
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Therapeutic Potential and Utility of Elacridar with Respect to P-glycoprotein Inhibition: An Insight from the Published In Vitro, Preclinical and Clinical Studies by Dash, Ranjeet Prasad, Jayachandra Babu, R., Srinivas, Nuggehally R.

“…The occurrence of efflux mechanisms via Permeability-glycoprotein (P-gp) recognized as an important physiological process impedes drug entry or transport…”
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Resveratrol‐loaded nanomedicines for cancer applications by Annaji, Manjusha, Poudel, Ishwor, Boddu, Sai H. S., Arnold, Robert D., Tiwari, Amit K., Babu, R. Jayachandra

“…Background Resveratrol (3, 5, 4′‐trihydroxystilbene), a natural polyphenol and phytoalexin, has drawn considerable attention in the past decade due to its wide…”
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Transdermal Delivery of Chemotherapeutics: Strategies, Requirements, and Opportunities by Neupane, Rabin, Boddu, Sai H. S., Abou-Dahech, Mariam Sami, Bachu, Rinda Devi, Terrero, David, Babu, R. Jayachandra, Tiwari, Amit K.

“…Chemotherapeutic drugs are primarily administered to cancer patients via oral or parenteral routes. The use of transdermal drug delivery could potentially be a…”
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Cardiolipin for Enhanced Cellular Uptake and Cytotoxicity of Thermosensitive Liposome-Encapsulated Daunorubicin toward Breast Cancer Cell Lines by Alrbyawi, Hamad, Boddu, Sai H S, Poudel, Ishwor, Annaji, Manjusha, Mita, Nur, Arnold, Robert D, Tiwari, Amit K, Babu, R Jayachandra

“…Daunorubicin (DNR) and cardiolipin (CL) were co-delivered using thermosensitive liposomes (TSLs). 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC),…”
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Hispolon Cyclodextrin Complexes and Their Inclusion in Liposomes for Enhanced Delivery in Melanoma Cell Lines by Poudel, Ishwor, Annaji, Manjusha, Wibowo, Fajar Setyo, Arnold, Robert D, Fasina, Oladiran, Via, Brian, Rangari, Vijaya, Peresin, Maria Soledad, Smith, Forrest, Dhanasekaran, Muralikrishnan, Tiwari, Amit K, Babu, R Jayachandra

“…Hispolon, a phenolic pigment isolated from the mushroom species Phellinus linteus, has been investigated for anti-inflammatory, antioxidant, and anticancer…”
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pH-Sensitive Liposomes for Enhanced Cellular Uptake and Cytotoxicity of Daunorubicin in Melanoma (B16-BL6) Cell Lines by Alrbyawi, Hamad, Poudel, Ishwor, Annaji, Manjusha, Boddu, Sai H S, Arnold, Robert D, Tiwari, Amit K, Babu, R Jayachandra

“…Daunorubicin (DNR) was delivered using a pH-sensitive liposomal system in B16-BL6 melanoma cell lines for enhanced cytotoxic effects. DNR was encapsulated…”
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Nanotechnology in Advancing Chimeric Antigen Receptor T Cell Therapy for Cancer Treatment by Kang, Xuejia, Mita, Nur, Zhou, Lang, Wu, Siqi, Yue, Zongliang, Babu, R Jayachandra, Chen, Pengyu

“…Chimeric antigen receptor (CAR) T cell therapy has emerged as a groundbreaking treatment for hematological cancers, yet it faces significant hurdles,…”
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Delignified wood aerogels as scaffolds coated with an oriented chitosan-cyclodextrin co-polymer for removal of microcystin-LR by Gomez-Maldonado, Diego, Reynolds, Autumn Marie, Burnett, Daniel J, Babu, R. Jayachandra, Waters, Matthew N, Peresin, Maria S

“…Nano-porous aerogels are an advantageous approach to produce low-density materials with high surface area, particularly when using biobased materials…”
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Nanomedicine Scale-up Technologies: Feasibilities and Challenges by Paliwal, Rishi, Babu, R. Jayachandra, Palakurthi, Srinath

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Advancing Cancer Therapy with Copper/Disulfiram Nanomedicines and Drug Delivery Systems by Kang, Xuejia, Jadhav, Sanika, Annaji, Manjusha, Huang, Chung-Hui, Amin, Rajesh, Shen, Jianzhong, Ashby, Jr, Charles R, Tiwari, Amit K, Babu, R Jayachandra, Chen, Pengyu

“…Disulfiram (DSF) is a thiocarbamate based drug that has been approved for treating alcoholism for over 60 years. Preclinical studies have shown that DSF has…”
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Tumor-Associated Macrophage Targeting of Nanomedicines in Cancer Therapy by Kang, Xuejia, Huang, Yongzhuo, Wang, Huiyuan, Jadhav, Sanika, Yue, Zongliang, Tiwari, Amit K, Babu, R Jayachandra

“…The tumor microenvironment (TME) is pivotal in tumor growth and metastasis, aligning with the "Seed and Soil" theory. Within the TME, tumor-associated…”
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Improved Ocular Delivery of Nepafenac by Cyclodextrin Complexation by Shelley, Haley, Grant, Makenzie, Smith, Forrest T., Abarca, Eva M., Jayachandra Babu, R.

“…Nepafenac is a nonsteroidal anti-inflammatory drug (NSAID), currently only available as 0.1% ophthalmic suspension (Nevanac®). This study utilized…”
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Microemulsion and Microporation Effects on the Genistein Permeation Across Dermatomed Human Skin by Chen, Li, Annaji, Manjusha, Kurapati, Sharmila, Ravis, William R., Jayachandra Babu, R.

“…This study reports the microemulsion (ME) effects on the permeation of genistein across normal (intact) and microporated human skin. The genistein formulation…”
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Microwave-Assisted Functionalization of Multi-Walled Carbon Nanotubes for Biosensor and Drug Delivery Applications by Thakur, Chanchal Kiran, Karthikeyan, Chandrabose, Abou-Dahech, Mariam Sami, Altabakha, Moawia Mohd A M, Al Shahwan, Moayad Jamal Saeed, Ashby, Jr, Charles R, Tiwari, Amit K, Babu, R Jayachandra, Moorthy, Narayana Subbiah Hari Narayana

“…Microwave-assisted synthetic methods have emerged as a popular technique for surface modification and the functionalization of multi-walled carbon nanotubes…”
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Ligand-conjugated multiwalled carbon nanotubes for cancer targeted drug delivery by Thakur, Chanchal Kiran, Karthikeyan, Chandrabose, Ashby, Jr, Charles R, Neupane, Rabin, Singh, Vishal, Babu, R Jayachandra, Narayana Moorthy, N S Hari, Tiwari, Amit K

“…Multiwalled carbon nanotubes (MWCNTs) are at the forefront of nanotechnology-based advancements in cancer therapy, particularly in the field of targeted drug…”
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Topical Delivery of Diacetyl Boldine in a Microemulsion Formulation for Chemoprotection against Melanoma by Al Saqr, Ahmed, Annaji, Manjusha, Poudel, Ishwor, Aldawsari, Mohammed F, Alrbyawi, Hamad, Mita, Nur, Dhanasekaran, Muralikrishnan, Boddu, Sai H S, Neupane, Rabin, Tiwari, Amit K, Babu, R Jayachandra

“…This study aimed to develop a microemulsion formulation for topical delivery of Diacetyl Boldine (DAB) and to evaluate its cytotoxicity against melanoma cell…”
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