Search Results - "Baboota, Ritesh K"
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Capsaicin induces "brite" phenotype in differentiating 3T3-L1 preadipocytes
Published in PloS one (29-07-2014)“…Targeting the energy storing white adipose tissue (WAT) by pharmacological and dietary means in order to promote its conversion to energy expending "brite"…”
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Cellular senescence in hepatocytes contributes to metabolic disturbances in NASH
Published in Frontiers in endocrinology (Lausanne) (22-08-2022)“…Cellular senescence is a state of irreversible cell cycle arrest and has been shown to play a key role in many diseases, including metabolic diseases. To…”
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Adult mice are unresponsive to AAV8-Gremlin1 gene therapy targeting the liver
Published in PloS one (19-02-2021)“…Gremlin 1 (GREM1) is a secreted BMP2/4 inhibitor which regulates commitment and differentiation of human adipose precursor cells and prevents the browning…”
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Capsaicin-induced transcriptional changes in hypothalamus and alterations in gut microbial count in high fat diet fed mice
Published in The Journal of nutritional biochemistry (01-09-2014)“…Obesity is a global health problem and recently it has been seen as a growing concern for developing countries. Several bioactive dietary molecules have been…”
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Chronic hyperinsulinemia promotes human hepatocyte senescence
Published in Molecular metabolism (Germany) (01-10-2022)“…Cellular senescence, an irreversible proliferative cell arrest, is caused by excessive intracellular or extracellular stress/damage. Increased senescent cells…”
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Finger millet bran supplementation alleviates obesity-induced oxidative stress, inflammation and gut microbial derangements in high-fat diet-fed mice
Published in British journal of nutrition (14-11-2014)“…Several epidemiological studies have shown that the consumption of finger millet (FM) alleviates diabetes-related complications. In the present study, the…”
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BMP4 and Gremlin 1 regulate hepatic cell senescence during clinical progression of NAFLD/NASH
Published in Nature metabolism (01-08-2022)“…The role of hepatic cell senescence in human non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) is not well understood. To…”
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Involvement of Glucagon in Preventive Effect of Menthol Against High Fat Diet Induced Obesity in Mice
Published in Frontiers in pharmacology (16-11-2018)“…Glucagon mediated mechanisms have been shown to play clinically significant role in energy expenditure. The present study was designed to understand whether…”
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Microarray based gene expression analysis of murine brown and subcutaneous adipose tissue: significance with human
Published in PloS one (26-05-2015)“…Two types of adipose tissues, white (WAT) and brown (BAT) are found in mammals. Increasingly novel strategies are being proposed for the treatment of obesity…”
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10
Emerging Role of Bone Morphogenetic Protein 4 in Metabolic Disorders
Published in Diabetes (New York, N.Y.) (01-02-2021)“…Bone morphogenetic proteins (BMPs) are a group of signaling molecules that belong to the TGF-β superfamily. Initially discovered for their ability to induce…”
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Cinnamaldehyde supplementation prevents fasting-induced hyperphagia, lipid accumulation, and inflammation in high-fat diet-fed mice
Published in BioFactors (Oxford) (01-03-2016)“…Cinnamaldehyde, a bioactive component of cinnamon, is increasingly gaining interest for its preventive and therapeutic effects against metabolic complications…”
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Functional food ingredients for the management of obesity and associated co-morbidities – A review
Published in Journal of functional foods (01-07-2013)“…Worldwide obesity has reached a pandemic proportion. World Health Organization (WHO) estimates that by 2020, two thirds of the global disease burden will be…”
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Dihydrocapsiate supplementation prevented high-fat diet–induced adiposity, hepatic steatosis, glucose intolerance, and gut morphological alterations in mice
Published in Nutrition research (New York, N.Y.) (01-03-2018)“…Despite the lipolytic and thermogenic properties of capsaicin, its putative use as a weight-lowering dietary supplement has been limited because of the burning…”
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Kodo millet whole grain and bran supplementation prevents high-fat diet induced derangements in a lipid profile, inflammatory status and gut bacteria in mice
Published in Food & function (01-03-2017)“…The protective role of kodo millet whole grain and bran supplementation in diet induced obesity has not been investigated. Here we have studied the role of…”
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Microarray Based Gene Expression Analysis of Murine Brown and Subcutaneous Adipose Tissue: Significance with Human: e0127701
Published in PloS one (01-05-2015)“…Background Two types of adipose tissues, white (WAT) and brown (BAT) are found in mammals. Increasingly novel strategies are being proposed for the treatment…”
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