Search Results - "Babkova, V. A."
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In silico consensus activity prediction, rational synthesis, and evaluation of antiglycation and antiplatelet activities of 3,6-disubstituted 1,2,4,5-tetrazines
Published in Russian chemical bulletin (01-04-2020)“…According to the in silico consensus activity prediction, a series of 3,6-disubstituted 1,2,4,5-tetrazines were synthesized as promising inhibitors of the…”
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2
Novel diphenylsulfimide antioxidants containing 2,6-di-tert-butylphenol moieties
Published in Russian chemical bulletin (01-11-2018)“…New diphenylsulfimide derivatives containing substituents with the 2,6-di- tert -butylphenol moiety at the nitrogen atom were synthesized. Their molecular…”
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3
2-Amino- and 2-hydroxymethylbenzimidazolium bromides as protein tyrosine phosphatase 1В (PTP1В) inhibitors and other targets associated with diabetes mellitus
Published in Russian chemical bulletin (01-04-2020)“…New 2-amino- and 2-hydroxymethylbenzimidazoles were synthesized and used to prepare the previously unknown 1,2,3-tri- and 1,2,3,5-tetrasubstituted…”
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4
Pharmacological Properties of 2-Aminobenzimidazole Halides and Imidazo[1,2-a]Benzimidazole Derivatives
Published in Russian journal of bioorganic chemistry (2022)“…Halides of 2-aminobenzimidazolium and derivatives of 9-substituted 2-(4-fluorophenyl)imidazo[1,2- a ]benzimidazoles have been studied for ten types of…”
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Hierarchical Assessment of the Structural Similarity of Pharmacologically Active Compounds
Published in Pharmaceutical chemistry journal (2021)“…Anew method for assessing the structural similarity of pharmacologically active substances based on a hierarchical description of the chemical structure by…”
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Synthesis and biological activity of 3-guanidino-6-R-imidazo[1,2-b]- and 6-guanidino-3-R-[1,2,4]triazolo[4,3-b][1,2,4,5]tetrazines
Published in Russian chemical bulletin (01-11-2018)“…The reaction of azoloannulated [1,2,4,5]tetrazines with guanidine was studied. New 3-guanidinoimidazo[1,2- b ]- and 6-guanidino[1,2,4]triazolo[4,3- b ]…”
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Synthesis and Antiglycation Activity of Novel S-Carboxyalkyl Derivatives of 2-Thiouracil
Published in Pharmaceutical chemistry journal (01-10-2019)“…S-carboxyalkyl derivatives of 2-thiouracil were synthesized and their pharmacological activity was studied. Several of the compounds were characterized by…”
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Synthesis and Pharmacological Activity of C(2)-Substituted Benzimidazoles
Published in Pharmaceutical chemistry journal (15-06-2019)“…Series of new compounds containing 2-pyrrolidinomethyl and 2-piperazinomethyl groups and 2-morpholino and 2-morpholinoethylamine substituents were synthesized…”
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