Search Results - "Babkova, Katerina"
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Design of Bis(1,10-phenanthroline) Copper(I)-Based Mechanochromic Indicators
Published in ACS omega (01-03-2022)“…In the growing field of single-molecule mechanochromism, the potential of transition metal complexes is yet to be examined. In this work, we have synthesized a…”
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Hierarchy of hydrogen bonding among constitutional isomers of hexanol
Published in Journal of molecular liquids (15-01-2024)“…•Hierarchy of hydrogen bonding strength established among all 17 constitutional isomers of hexanol.•Heat capacities of 16 aliphatic hexanols determined by…”
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7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment
Published in Molecules (Basel, Switzerland) (10-12-2015)“…Alzheimer's disease (AD) is a debilitating progressive neurodegenerative disorder that ultimately leads to the patient's death. Despite the fact that novel…”
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In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2019)“…A combination of biochemical, biophysical and biological techniques was used to study calf thymus DNA interaction with newly synthesized 7-MEOTA-tacrine…”
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Tacrine–Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity
Published in Journal of medicinal chemistry (25-11-2015)“…Coupling of two distinct pharmacophores, tacrine and trolox, endowed with different biological properties, afforded 21 hybrid compounds as novel…”
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Prolyl oligopeptidase and its role in the organism: attention to the most promising and clinically relevant inhibitors
Published in Future medicinal chemistry (01-06-2017)“…Prolyl oligopeptidase (POP), also called prolyl endopeptidase, is a cytosolic enzyme investigated by several research groups. It has been proposed to play an…”
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