Search Results - "Babkin, Gennady A."

The novel peptide LCGM-10 attenuates metabotropic glutamate receptor 5 activity and demonstrates behavioral effects in animal models by Malyshev, Anton V, Pavshintcev, Vsevolod V, Mitkin, Nikita A, Sukhanova, Iuliia A, Gedzun, Vasilina R, Zlobin, Alexander S, Doronin, Igor I, Babkin, Gennady A, Sawyer, Tomi K

“…We employed a structural bioinformatics approach to develop novel peptides with predicted affinity to the binding site for negative allosteric modulators…”
Get full text

PeptoGrid-Rescoring Function for AutoDock Vina to Identify New Bioactive Molecules from Short Peptide Libraries by Zalevsky, Arthur O, Zlobin, Alexander S, Gedzun, Vasilina R, Reshetnikov, Roman V, Lovat, Maxim L, Malyshev, Anton V, Doronin, Igor I, Babkin, Gennady A, Golovin, Andrey V

“…Peptides are promising drug candidates due to high specificity and standout safety. Identification of bioactive peptides de novo using molecular docking is a…”
Get full text

The Novel Peptide Chm-273s Has Therapeutic Potential for Metabolic Disorders: Evidence from In Vitro Studies and High-Sucrose Diet and High-Fat Diet Rodent Models by Mitkin, Nikita A, Pavshintcev, Vsevolod V, Sukhanova, Iuliia A, Doronin, Igor I, Babkin, Gennady A, Sadagurski, Marianna, Malyshev, Anton V

“…The aim of this study was to develop a novel peptide potentially applicable for the treatment of metabolic conditions, such as obesity and type 2 diabetes…”
Get full text

In silico Screening and Behavioral Validation of a Novel Peptide, LCGA-17, With Anxiolytic-Like Properties by Malyshev, Anton V, Sukhanova, Iuliia A, Zlobin, Alexander S, Gedzun, Vasilina R, Pavshintsev, Vsevolod V, Vasileva, Ekaterina V, Zalevsky, Arthur O, Doronin, Igor I, Mitkin, Nikita A, Golovin, Andrey V, Lovat, Maxim L, Kovalev, Georgy I, Zolotarev, Yurii A, Kuchumov, Askar R, Babkin, Gennady A, Luscher, Bernhard

“…The aim of the study was to develop better anxiolytics and antidepressants. We focused on GABA receptors and the α2δ auxiliary subunit of V-gated Ca channels…”
Get full text

Peptide LCGA-17 Attenuates Behavioral and Neurochemical Deficits in Rodent Models of PTSD and Depression by Malyshev, Anton V, Sukhanova, Iuliia A, Ushakova, Valeria M, Zorkina, Yana A, Abramova, Olga V, Morozova, Anna Y, Zubkov, Eugene A, Mitkin, Nikita A, Pavshintsev, Vsevolod V, Doronin, Igor I, Gedzun, Vasilina R, Babkin, Gennady A, Sanchez, Sergio A, Baker, Miah D, Haile, Colin N

“…We have previously described the LCGA-17 peptide as a novel anxiolytic and antidepressant candidate that acts through the α2δ VGCC (voltage-gated calcium…”
Get full text

From land to water: “Sunken” T-maze for associated learning in cichlid fish by Gedzun, Vasilina R., Sukhanova, Iuliia A., Aliper, Gleb M., Kotova, Maria M., Melnik, Nikolai O., Karimova, Elizaveta B., Voronkova, Anastasia S., Coffman, Alina, Pavshintcev, Vsevolod V., Mitkin, Nikita A., Doronin, Igor I., Babkin, Gennady A., Malyshev, Anton V.

“…The study introduced and evaluated learning paradigms for Maylandia callainos cichlids using a modified version of the rodent T-maze, filled with tank water…”
Get full text