Oxidative stress and anti-oxidative defense in schoolchildren residing in a petrochemical industry environment

Oxidative stress and anti-oxidative defense in schoolchildren residing in a petrochemical industry environment

Objective To evaluate the possible relationship between industrial air pollution and oxidative stress in schoolchildren by comparing parameters from children residing in two nearby localities with contrasting environmental conditions. Participants 42 schoolchildren (12–15 years) from Pancevo (site o...

Full description

Saved in:
Bibliographic Details
Published in:Indian pediatrics Vol. 47; no. 3; pp. 233 - 239
Main Authors: Vujovic, A., Kotur-Stevuljevic, J., Kornic, D., Spasic, S., Spasojevic-Kalimanovska, V., Bogavac-Stanojevic, N., Stefanovic, A., Deanovic, M., Babka, S., Aleksic, B., Jelic-Ivanovic, Z.
Format: Journal Article
Language:English
Published: India Springer-Verlag 01-03-2010
Subjects:
Adolescent
Air Pollutants - blood
Air Pollutants - poisoning
Antioxidants - metabolism
Case-Control Studies
Child
Extraction and Processing Industry
Female
Humans
Male
Malondialdehyde - blood
Maternal and Child Health
Medicine
Medicine & Public Health
Oxidative Stress - drug effects
Pediatric Surgery
Pediatrics
Petroleum
Research Paper
Students
Oxidative stress
Air pollution
Cardiovascular disease
Environment
Anti-oxidative defense
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective To evaluate the possible relationship between industrial air pollution and oxidative stress in schoolchildren by comparing parameters from children residing in two nearby localities with contrasting environmental conditions. Participants 42 schoolchildren (12–15 years) from Pancevo (site of Serbia’s largest petrochemical installation) formed the exposed group. 82 schoolchildren from Kovacica village, located 30 km north of Pancevo, formed the non-exposed group. Methods Oxidative stress status, anti-oxidative defense parameters, paraoxonase-1 status, lipid status, glucose concentration and leukocyte counts were compared in two groups. Results The children from Pancevo showed higher level of oxidative stress demonstrated by an elevated malondialdehyde concentration ( P <0.001) and decreased superoxide dismutase activity ( P <0.01) in comparison to the non-exposed group. Conclusions The results suggested a relationship between the presence of air pollutants and increased oxidative stress in schoolchildren residing in an industrial environment.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0019-6061
0974-7559
DOI:10.1007/s13312-010-0045-y